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Unit 6 AP Biology Part 1

Total questions: 35

Worksheet time: 27mins

Name
Class
Date
1.

Which of the following are pyrimidines?

a)

adenine and cytosine

b)

adenine and guanine

c)

adenine and thymine

d)

cytosine and guanine

e)

cytosine and thymine

2.

A nucleic acid contains 35% adenine, 36% thymine, 14% guanine, and 15% cytosine. This nucleic acid is

a)

single-stranded RNA

b)

single-stranded DNA

c)

double-stranded RNA

d)

double-stranded DNA

3.

A nucleic acid consists of 29% cytosine, 35% uracil, 10% adenine, and 26% guanine. This nucleic acid is

a)

single-stranded RNA

b)

single-stranded DNA

c)

double-stranded RNA

d)

double-stranded DNA

4.

Which is not a component of DNA nucleotides?

a)

Ribose sugar

b)

Phosphate

c)

Nitrogenous base

d)

Deoxyribose sugar

5.

Eukaryotic DNA is located in

a)

the nucleus

b)

the cytoplasm

c)

anywhere in the cell

6.

During transcription, what is the relationship between DNA and RNA?

a)

DNA is the template, RNA reads DNA in 3' -> 5' direction

b)

DNA is the template, RNA reads DNA in 5' -> 3' direction

c)

RNA is the template, DNA reads RNA in 3' -> 5' direction

d)

RNA is the template, DNA reads RNA in 5' -> 3' direction

7.

What is the sequence of nucleotides on mRNA read in triplets called?

a)

anticodon

b)

codon

c)

triplet box

d)

wobble

8.

Identify which molecules bind to the promoter region

a)

Ligase

b)

Topoisomerase

c)

DNA polymerase

d)

RNA polymerase

9.

How does the DNA in a prokaryote differ from a eukaryote?

a)

Prokaryote has circular DNA, Eukaryotes has linear DNA

b)

Prokaryote has single stranded DNA, Eukaryotes has double stranded DNA

c)

Prokaryote has linear DNA, Eukaryotes has circular DNA

d)

Prokaryote has double stranded DNA, Eukaryotes has single stranded DNA

10.

Describe the difference between the synthesis of the leading and lagging strands.

a)

directionality: leading = 3' -> 5', lagging = 5' -> 3'

b)

synthesis continuity: leading = discontinuous & lagging = continuous

c)

directionality: leading = 5' -> 3', lagging = 3' -> 5'

d)

synthesis continuity: leading = continuous & lagging = discontinuous

11.

Which of the following demonstrates base pairing rules to 5' - CAGGT - 3'?

a)

3' - TGGAC - 5'

b)

3' - GTCCA - 5'

c)

5' - GTCCA - 3'

d)

5' - CAGGT - 3'

12.

Translation is a process where:

a)

a polypeptide sequence is produced from a sequence of rRNA codons.

b)

a polypeptide sequence is produced from a sequence of tRNA codons.

c)

a polypeptide sequence is produced from a sequence of mRNA codons.

d)

a DNA nucleotide sequence is used to produce mRNA codon sequence.

13.

Where on the DNA does the enzyme responsible for transcription bind?

a)

Promoter

b)

Enhancer

c)

Polyadenylation sequence

d)

Start codon

14.

Where does transcription take place in a eukaryote?

a)

Nucleus

b)

Endoplasmic reticulum

c)

Cytosol

d)

Ribosome

15.

Which of the following is the site for translation?

a)

Ribosome

b)

Nucleus

c)

Golgi bodies

d)

Cytosol

16.

Which of the following is the start codon?

a)

UGA

b)

AUG

c)

GUA

d)

GAU

17.

What is the function of the P site in the large subunit?

a)

To phosphorylate the polypeptide

b)

To hold the growing polypeptide

c)

To assist with the tertiary structure of the polypeptide

d)

To perform the base pairing for the polypeptide

18.

Which of the following describes the process of translation?

a)

Codon recognition, peptide bond formation, translocation

b)

Anticodon recognition, ionic bond formation, translocation

c)

Codon recognition, ionic bond formation, translocation

d)

Anticodon recognition, peptide bond formation, translocation

19.

How does the DNA in a prokaryote differ from a eukaryote?

a)

Prokaryote has circular DNA, Eukaryotes has linear DNA

b)

Prokaryote has single stranded DNA, Eukaryotes has double stranded DNA

c)

Prokaryote has linear DNA, Eukaryotes has prokaryote DNA

d)

Prokaryote has double stranded DNA, Eukaryotes has single stranded DNA

20.

Identify which of the following best describes purines and pyrimidines.

a)

Purines (C, T, & U) have single ring, Pyrimidines (A & G) have double ring

b)

Purines (C, T, & U) have double ring, Pyrimidines (A & G) have single ring

c)

Purines (A & G) have single ring, Pyrimidines (C, T, & U) have double ring

d)

Purines (A & G) have double ring, Pyrimidines (C, T, & U) have single ring

21.

Which enzyme is responsible for relaxing supercoiling in front of the replication fork?

a)

helicase

b)

DNA polymerase

c)

topoisomerase

d)

ligase

22.

Which enzyme is responsible for unzipping the DNA strands?

a)

helicase

b)

DNA polymerase

c)

topoisomerase

d)

ligase

23.

Which enzyme is responsible for joining the fragments on the lagging strand?

a)

helicase

b)

DNA polymerase

c)

topoisomerase

d)

ligase

24.

How do the three types of RNA work together?

a)

mRNA carries message, tRNA carries amino acids, and rRNA makes ribosome

b)

mRNA makes ribosomes, tRNA carries amino acids, and rRNA relays information

c)

mRNA carries amino acids, tRNA transfer message, and rRNA makes ribosome

d)

mRNA is made, tRNA holds the DNA in place, and rRNA removes the deoxyribose

25.

Where does translation take place in prokaryotes & eukaryotes?

a)

Prokaryotes - cytosol; Eukaryotes - cytosol or nucleus

b)

Prokaryotes - cytosol or rough ER; Eukaryotes - cytosol

c)

Prokaryotes - cytosol; Eukaryotes - cytosol or rough ER

d)

Prokaryotes - cytosol or nucleus; Eukaryotes - cytosol

26.
What is the flow of genetic information in cells from DNA to protein? (Central Dogma)
a)
RNA to DNA to protein
b)
DNA to RNA to protein
c)
protein to DNA to RNA
d)
RNA to protein to DNA
27.
Which RNA bases would pair with TACGAA in transcription
a)
AUGCUU
b)
ATGCTT
c)
GCATCC
d)
GCAUCC
28.

How can a person's muscle cells have the same exact DNA sequences as their nerve cells even though they look and perform completely different?

a)

The two different cells become mutated

b)

The proteins expressed in each cell are different

c)

They actually have different DNA in the two types of cells.

d)

The genome of the different cells changes

29.
RNA polymerase moves in which direction along the DNA?
a)
5' to 3' 
b)
3' to 5' along the template strand
c)
3' to 5' along nontemplate(coding) strand
d)
5' to 3' along the template strand
30.
Which of the following is an example of post-transcriptional control of gene expression?
a)
the addition of methyl groups to cytosine bases of DNA
b)
the binding of transcription factors to a promoter
c)
the removal of introns and splicing together of exons
d)
gene amplification contributing to cancer
31.
The parts of a gene that do NOT code for amino acids in a protein are called
a)
introns
b)
exons
c)
codons
d)
anticodons
32.
The production of mature mRNA in eukaryotes involves
a)
cutting introns out and spicing exons together
b)
adding the 5' cap
c)
adding the 3' poly A tail
d)
all of these are correct
33.
What is the function of the poly-A tail in mRNA?
a)
to add modified guanin to the 3' end of the mRNA
b)
to indicate the site of translational termination
c)
to code for the binding of RNA polymerase to the DNA
d)
to help protect the mRNA from degradation by hydrolytic enzymes 
34.
What amino acid sequence will be produced based on the mRNA codon sequence
5'-AUG-UCU-UCG-UUA-UCC-UUG-3'
a)
met-ser-leu-ser-leu-ser
b)
met-ser-ser-leu-ser-leu
c)
met-leu-phe-arg-glu-glu
d)
met-glu-arg-arg-glu-leu
35.
Smaller segments of RNA nucleotides that transport amino acids to the ribosomes.
a)
mRNA
b)
tRNA
c)
rRNA
d)
DNA