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Junior Biology Cell Cycle, Mitosis, Cancer Review

Total questions: 60

Worksheet time: 1hrs 7mins

Name
Class
Date
1.
In which phase does the cell spend most of it's life?
a)
Interphase
b)
Nuclear Division
c)
Telophase
d)
Mitosis
2.
DNA will condense into...
a)
Centromeres
b)
Chromosomes
c)
Nuclei
d)
Spindle fibers
3.
What phase of mitosis is pictured?
a)
Metaphase
b)
Telophase
c)
Prophase
d)
Anaphase
4.
The process by which the nuclear material is divided equally between two new cells
a)
mitosis
b)
cancer
c)
spindle
d)
centromere
5.

Structure A refers to the _____.

a)

chromatid

b)

chromosome

c)

centromere

6.
Fruit fly body cells have 8 chromosomes. After mitosis, you would expect a resulting fruit fly daughter cell to have -
a)
16 chromosomes.
b)
46 chromosomes.
c)
8 chromosomes.
d)
4 chromosomes.
7.
Structure (b) is a ____.
a)
chromosome
b)
chromatid
c)
centromere
8.
Name the phase:
a)
Prophase
b)
Metaphase
c)
Anaphase
d)
Telophase
9.

Mitosis in animals creates which kind of cells

a)

Diploid

b)

Haploid

c)

Gametes

d)

Somatic

10.
Structure (c) is a ____.
a)
chromosome
b)
chromatid
c)
centromere
11.

If a cell has 20 chromosomes and under goes mitosis twelve times how many chromosomes will the daughter cell have?I

a)

20

b)

40

c)

240

d)

10

12.

Phase?

a)

prophase

b)

anaphase

c)

metaphase

d)

telophase

e)

interphase

13.

Phase?

a)

prophase

b)

anaphase

c)

metaphase

d)

telophase

e)

interphase

14.

Phase?

a)

prophase

b)

anaphase

c)

metaphase

d)

telophase

e)

interphase

15.

Phase?

a)

prophase

b)

anaphase

c)

metaphase

d)

telophase

e)

interphase

16.

Phase?

a)

prophase

b)

anaphase

c)

metaphase

d)

telophase

e)

interphase

17.

Phase?

a)

prophase

b)

anaphase

c)

metaphase

d)

telophase

e)

interphase

18.

Which photo shows chromosomes lining up along the cell equator (aka metaphase plate)?

a)
b)
c)
d)
19.

Which photo shows sister chromatids being pulled by spindle fibers to opposite poles of the parent cell?

a)
b)
c)
d)
20.

Which photo shows the formation of a cell plate (growing cell wall) between the two daughter plant cells?

a)
b)
c)
d)
21.

This cell photo was taken while the nuclear membrane was being formed around chromosomes

a)
b)
c)
d)
22.

Q3. The process in which the cytoplasmic content of the cell is divided into two new daughter cells is called _____.

a)

meiosis

b)

cytokinesis

c)

replication

d)

mitosis

23.

Q5. Which of the following events occurs during the metaphase of mitosis?

a)

Chromosomes begin to segregate and the enzyme separase cleaves the centromere

b)

Chromosomes move to the middle of the cell, attached to microtubules.

c)

The chromosomes condense and the centrosomes move to opposite sides of the cell.

d)

The nuclear membrane reforms around the chromosomes.

24.

Q6. In somatic cell cycle, DNA synthesis takes place

a)

G1 phase

b)

G2 Prophase

c)

S phase

d)

Prophase of mitosis

25.

Q7. In Somatic cell cycle

a)

In G1 phase DNA content is double the amount of DNA present in the origin cell

b)

G2 phase follows mitotic phase

c)

a short phase followed b along mitotic phase

d)

DNA replication takes place in S phase

26.

Q12. Cell plate formation is present in

a)

Bacterial Cell

b)

Viruses

c)

Animal Cell

d)

Plant Cell

27.
Which of the following is a type of protein that regulates the cell cycle? 
a)
actin 
b)
myosin 
c)
cyclin 
d)
pepsin 
28.
Highly coiled strand of DNA
a)
Chromatin
b)
Chromosome
c)
Sister Chromatid
d)
Centeromere
29.
________________is a critical point where stop and go signals can regulate the cycle
a)
Metastasis
b)
Checkpoint
c)
Malignant
d)
Benign
30.
The chromosome in the diagram 
a)
has been replilcated
b)
consists of 2 copies of 1 chromosome
c)
is about to go through cell division
d)
all of the above.
31.
Cells of organism must replicate for ?
a)
growth
b)
repair of damaged cells
c)
replacement of dying cells.
d)
All of the above
32.

Phase involving microtubules to separate sister chromatids to opposite poles of the cell.

a)

anaphase

b)

metaphase

c)

prophase

d)

telophase

33.

Which checkpoint involves ensuring all microtubules are attached to kinetochores?

a)

G1

b)

G2

c)

M

d)

S

34.

Which of the following describes the order of processes in the cell cycle?

a)

Interphase, Prophase, Metaphase, Anaphase, Telophase, Cytokinesis

b)

Prophase, Metaphase, Interphase, Anaphase, Telophase, Cytokinesis

c)

Interphase, Metaphase, Anaphase, Prophase, Cytokinesis, Telophase

d)

Prophase, Anaphase, Metaphase, Interphase, Cytokinesis

35.

Phase involving pairing of sister chromatids and condensation of chromatin into chromosomes

a)

Anaphase

b)

Metaphase

c)

Prophase

d)

Telophase

36.

Which of the following describes the result of mitosis?

a)

2 identical, haploid cells

b)

4 non-identical haploid cells

c)

2 identical, diploid cells

d)

4 non-identical, diploid cells

37.

Which checkpoint involves determining whether the cell should divide?

a)

G1

b)

G2

c)

M

d)

S

38.

Phase involving formation of nuclear envelope around separated chromosomes

a)

Anaphase

b)

Metaphase

c)

Prophase

d)

Telophase

39.

Phase involving sister chromatids aligning on plate in middle of cell.

a)

anaphase

b)

metaphase

c)

prophase

d)

telophase

40.

Which checkpoint involves ensuring all DNA has been replicated and "no" errors exist?

a)

G1

b)

G2

c)

M

d)

S

41.

Which of the following occurs BEFORE the process of mitosis?

a)

Sister chromatids pair up

b)

DNA replicates

c)

Chromatin is condensed to chromosomes

d)

Cytoplasm is divided between two cells

42.
Put the following stages of the cell cycle in order: G2, S, G1, M. 
a)
G1, S, G2, M
b)
S, G1, G2, M
c)
G1, M, G2, S
d)
M, G1, S, G2
43.

During most of interphase, DNA is found in a relaxed form called

a)

chromosome

b)

centromere

c)

centriole

d)

chromatin

44.

The cell cycle is regulated by this

a)

cyclins

b)

stem cells

c)

cyclin-dependent kinases

d)

both cyclins and cyclin-dependent kinases

45.

When cells go through mitosis repeatedly without entering interphase, this results

a)

arthritis

b)

cancer

c)

mutation

d)

diabetes

46.

Cells grow, carry out normal functions, and copy their organelles.

a)

G1

b)

S

c)

G2

d)

M phase

47.

Cells go through additional growth.

a)

G1

b)

S

c)

G2

d)

M phase

48.

Some scientists name the stage where cells carry out their normal functions but are unlikely to divide. The name they give this stage is _________.

a)

G0

b)

G1

c)

G2

d)

G3

49.

To stay alive, a cell needs materials to move in and out across its membrane. As a cell grows bigger, its volume increases _____ than its surface area. At a certain point, the cell’s volume would be _____ compared to the area available for materials to move in and out.

a)

faster / too small

b)

faster / too large

c)

slower / too small

d)

slower / too large

50.

Which checkpoint may initiate G0?

a)

G1 Checkpoint

b)

G2 Checkpoint

c)

G3 Checkpoint

d)

M Checkpont

51.

Which of the following cells do not stay in G0

a)

muscle cells

b)

nerve cells

c)

skin cells

d)

heart cell

52.

Protein that concentration varies depending on the specific phases of the cell cycle

a)

cyclins

b)

CDK

c)

cyclin-dependent kinases

d)

kinases

53.

Enzymes that are only active during the cell cycle when a cyclin is present

a)

cyclins

b)

CBK

c)

cyclin-dependent kinases

d)

kinases

54.

Hormones released by cells that stimulate cell growth. They signal/initiate a transduction pathway which leads to CDKs being activated for progression through the cell cycle

a)

growth factors

b)

contact/density inhibition

c)

anchorage dependence

d)

CDK complexes

55.

Cell surface receptors recognize contact with other cells which initiates a signal transduction pathway that stops the cell cycle at G1 phase.

a)

growth factors

b)

contact/density inhibition

c)

anchorage dependence

d)

CDK complexes

56.

A cell regulator that relies on a cells attachment to other cells or the extracellular matrix to divide

a)

growth factors

b)

contact/density inhibition

c)

anchorage dependence

d)

CDK complexes

57.

Which are not true of cancer cells

a)

do not follow checkpoints

b)

divide indefinitely in a petri dish

c)

evade apoptosis

d)

stop dividing if there is errors at the different checkpoints

58.

How do mutations in proto-oncogenes contribute to the development of cancer?

a)

Mutations in proto-oncogenes can lead to uncontrolled cell division, contributing to the development of cancer.

b)

Mutations in proto-oncogenes prevent the development of cancer.

c)

Mutations in proto-oncogenes have no effect on the development of cancer.

d)

Mutations in proto-oncogenes slow down the development of cancer.

59.

How is the cell cycle regulated?

a)

The cell cycle is regulated by a complex network of proteins and checkpoints.

b)

The cell cycle is not regulated at all.

c)

The cell cycle is regulated by external factors such as weather.

d)

The cell cycle is regulated by random chance.

60.

What are tumor suppressor genes?

a)

Tumor suppressor genes are genes that only regulate cell division in certain types of cells.

b)

Tumor suppressor genes are genes that help regulate cell division and prevent the formation of tumors.

c)

Tumor suppressor genes are genes that promote cell division and encourage the formation of tumors.

d)

Tumor suppressor genes are genes that have no effect on cell division or tumor formation.

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