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Biotechnology Review

Total questions: 56

Worksheet time: 51mins

Name
Class
Date
1.
The process of changing the genetic material of a living organism 
a)
Genetic Modification
b)
Taxonomy
c)
Adapting
d)
Bioremediation
2.

This is the practice of producing a genetically identical cell or organism

a)

Cloning

b)

Gel Electrophoresis

c)

Genetic Engineering

d)

DNA Fingerprinting

3.
A lab technique used in crime fighting to prove a suspects innocence or guilt is known as:
a)
genetic engineering
b)
PCR
c)
electrophoresis
d)
gene therapy
4.
What is recombinant DNA?
a)
Adding DNA from one organism into the DNA of another
b)
DNA which has been changed over generations by natural selection
c)
DNA that causes genetic disorders
d)
DNA that has been sequenced
5.

Why is Dolly the sheep considered a clone?

a)

the source of Dolly's DNA is a single cell taken from an adult donor

b)

the DNA molecules in each of Dolly's cells are different

c)

Dolly has a mix of genes from her foster mother and the sheep that donated a nucleus of one of its cells

d)

Dolly is genetically identical to her offspring

6.
True or False: Gel electrophoresis allow scientist to compare DNA of different individuals.
a)
True
b)
False
7.

Which suspect left the blood stain?

a)

Bob

b)

Sue

c)

John

d)

Lisa

8.

The process that has been used for centruries to create purebred animals such as black labs is called

a)

recombinant DNA

b)

cloning

c)

selective breeding

9.

Problems with cloning are

a)

creating too many embryos that are unneeded

b)

premature aging and a high failure rate

c)

they have a tendency to overpopulate

10.

The insertion of a gene of interest into a bacterial DNA loop is called

a)

recombinant DNA

b)

insertion technique

c)

mutation propagation

11.

Which of the following is an example of a GMO

a)

Bt Corn

b)

Black Lab Puppies

c)

Dolly the sheep

12.

The graphic shown here is called a

a)

PCR

b)

DNA fingerprint

c)

electrophoresis gel

13.

This is the practice of cutting DNA and separating it by the size of the pieces

a)

Cloning

b)

Gel Electrophoresis

c)

Genetic Engineering

d)

DNA Fingerprinting

14.

Which kitten is most likely the offspring of this cat?

a)

1

b)

2

c)

3

d)

4

15.

This is the practice of choosing individuals of a species to mate based on their desirable characteristics

a)

Bacterial recombination

b)

Natural selection

c)

Genetic modification

d)

Selective breeding

16.

Which of these is the correct definition of genetic modification/genetic engineering?

a)

Choosing individuals to mate based on desired characteristics

b)

Observing genetic changes in populations over time based on adaptive traits

c)

Extracting stem cells to differentiate into specialized tissues

d)

Altering the DNA of an organism at the molecular level

17.

During gel electrophoresis, the _______ pieces of DNA move farthest down the gel

a)

lightest

b)

heaviest

c)

ugliest

d)

deadliest

18.

________ are used to ________ DNA pieces by ________

a)

Restriction enzymes, connect, fission

b)

Restriction enzymes, isolate, "snipping"

c)

Plasmids, connect, fission

d)

Plasmids, isolate, "snipping"

19.

Which is a concern of scientists when genetically modifying plants?

a)

Plants will pass on diseases to animals.

b)

There will be a decrease in biodiversity.

c)

Plants will have a longer growing season.

d)

There will be a decrease in revenue for pesticide manufacturers.

20.

Which best describes a controversial issue associated with the use of genetically modified crops?

a)

the use of genetically modified crops to increase potential yield

b)

the short term use of genetically modified crops in famine stricken countries

c)

the development of genetically modified crops which are resistant to herbicides

d)

the long term effects which may arise from the use of genetically modified crops

21.

Bacteria cells can be used to produce insulin for the treatment of diabetes in humans. Which best explains how the bacteria cells are able to produce insulin for humans?

a)

The bacteria have been grown on a petri dish containing insulin.

b)

The bacteria have been genetically engineered to contain the DNA needed to produce insulin.

c)

The bacteria have been exposed to radioactivity to create mutant strains capable of producing insulin.

d)

The bacteria have been grown on a petri dish containing sugar; the bacteria produce insulin in response to the sugar.

22.

Which area of biotechnology would most likely create ethical issues within human society?

a)

insulin production by bacteria

b)

organ cloning for use in transplants

c)

genetic engineering to improve agricultural yields

d)

DNA and forensic testing of crime scene evidence

23.

Which was most likely the earliest way biotechnology was studied by humans?

a)

finding evidence of crimes

b)

making new medicines to cure sicknesses

c)

discovering the cause of hereditary diseases

d)

breeding better varieties of crops and livestock

24.

Which would be reduced as a result of the development of pest-resistant crops?

a)

use of organic fertilizers

b)

use of chemical insecticides

c)

practice of crop rotation techniques

d)

practice of hydroponic farming techniques

25.

Restriction enzymes are analogous to what common school supply?

a)

glue

b)

scissors

c)

paper

d)

highlighter

26.

What is a plasmid?

a)

a section of the human genome

b)

a material that cuts DNA

c)

viral DNA

d)

an accessory piece of DNA found in bacteria

27.

If a linear piece of DNA contains 3 recognition sites for a restriction enzyme. How many pieces will be produced when the restriction enzyme cuts the DNA?

a)

2

b)

3

c)

4

d)

5

e)

6

28.

Sticky ends are produced when the restriction enzyme cuts in a:

a)

staggered manner

b)

straight through the DNA

29.

A plasmid is larger than a bacterial genome

a)

True

b)

False

30.

How many times do you want a restriction enzyme to cut a human genome in order to cut out the gene of interest to insert into a plasmid?

a)

1 - through the gene

b)

2 - on either side of the gene

c)

3 - through the gene and on either side of the gene

d)

4 - twice on each side of the gene

31.

What enzyme is used to ensure that the recombinant DNA created is bonded together along the sugar-phosphate backbone?

a)

DNA polymerase

b)

RNA polymerase

c)

ligase

d)

helicase

32.

Clones have the exact same:

a)

Personalities

b)

Physical appearances

c)

Intelligence levels

d)

Genetic material

33.

What was the significance of Dolly the Sheep?

a)

She was the first organism ever cloned

b)

She was the first animals clone made using SCNT.

c)

She was the first animal cloned as an embryo

d)

She was the first animal to be cloned multiple times

34.

How many sheep were required to create Dolly?

a)

3

b)

2

c)

1

d)

0

35.

What did the scientist prove when cloning Dolly?

a)

That anything could be cloned

b)

That adult cell carry workable versions of all genes necessary to produce an entire new organism

c)

You cant really clone anything, its just a lie

d)

You only can clone animals

36.

What is the first cloned mammal?

a)

goat

b)

cat

c)

sheep

d)

cow

37.
A clone can be BEST thought of as a(n)  _____ created in the lab. 
a)
identical twin
b)
GMO
c)
science fiction experiment
38.
SCNT stands for . . . 
a)
Somatic Cell Nuclear Transfer
b)
Somatic Cell Natural Transcription
c)
Somatic Cell Nerve Transfer
d)
Skin Cell Nuclear Translation
39.
A somatic cell contains _______________
a)
Half the number of chromosomes coming from one parent
b)
a complete set of chromosomes coming from both parents
40.
Why might people be against cloning? 
a)
It's creepy
b)
It can cause unknown defects
c)
It is detrimental to genetic diversity
d)
All of the above
41.
In cloning, what is the purpose of the surrogate mother? 
a)
Donate her DNA
b)
Donate her egg cell
c)
Incubate and carry the baby until birth
d)
Nothing.  She's useless.
42.

There are now companies that will clone your pet cat for a fee.

a)

true

b)

false

43.

It is currently illegal to use SCNT to create a human being in the United States.

a)

true

b)

false

44.
In order to insert a human gene into plasmid, both must 
a)
code for the same gene product.
b)
be cut by the same restriction enzyme.
c)
originate from the same type of cell.
d)
have identical sequences.
45.
An organism that contains DNA from another organism is called:
a)
transatlantic
b)
recombinant
c)
binary
d)
selective species
46.
What is this
a)
plasmid
b)
recombinant bacterium
c)
recombinant DNA
d)
sticky ends
47.
Which two bear species are most closely related?
a)
Bear 1 and Bear 2
b)
Bear 1 and Bear 3
c)
Bear 2 and Bear 3
d)
There’s no way to tell
48.
The process to the right is best used for which of the following?
a)
Cloning humans
b)
Creating antibiotics
c)
Creating human insulin
d)
Causing cells to divide
49.
Which option most closely relates to how CRISPR works?
a)
"shake and bake"
b)
"cut and paste"
c)
"hide and seek"
d)
"live and love"
50.

What is the role of the guide RNA?

a)

It helps the cell repair the DNA

b)

ensures that the Cas9 enzyme cuts at the right point in the genome

c)

Recognizes PAM sequences and opens up the DNA

d)

makes a cut across both strands of the DNA

51.

When two organisms that have very similar or the same characteristics are mated resulting in the prevalence of genetic disorders.

a)

Hybridization

b)

Cloning

c)

Inbreeding

d)

Gene Splicing

52.

Adding or deleting segments of genes to correct or get rid of genetic disorders.

a)

Gene Splicing

b)

Genetic Screening

c)

Gene Therapy

d)

Stem Cell Therapy

53.

Engineering food to make crops that can grow in poor soil conditions, resist disease, tolerate drought, repel insects, etc.

a)

Cloning

b)

Genetically Modified Food

c)

Selective Breeding

d)

Transgenic Organisms

54.
What synthetic molecule is used to cut DNA open at a specific location and create sticky ends for the gene of interest to be attached?
a)
vector or plasmid 
b)
restriction enzyme
c)
DNA scissors 
d)
DNA Helicase
55.
The gene of interest + vector = __________
a)
recombinant DNA 
b)
restriction enzyme 
c)
transformation 
d)
genome 
56.

True or False-There could be possible benefits to GMOs.

a)

True

b)

False