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WorksheetsNCM 112 Lecture (Oxygen-Transport)
Total questions: 80
Worksheet time: 7hrs 40mins
What is the most common type of anemia?
sickle cell anemia
aplastic anemia
iron-deficiency anemia
pernicious anemia
Which type of anemia is caused by a lack of vitamin B12?
pernicious anemia
sickle cell anemia
iron-deficiency anemia
aplastic anemia
What is the main characteristic of sickle cell anemia?
Low white blood cell count
High red blood cell count
Abnormal hemoglobin
Normal hemoglobin
Which type of anemia is inherited and affects the production of normal hemoglobin?
Hemolytic Anemia
Sickle Cell Anemia
Aplastic Anemia
Iron-deficiency Anemia
What is the cause of aplastic anemia?
Excessive production of red blood cells
Infection in the bone marrow
Genetic mutation in the blood cells
Decrease in the bone marrow's ability to produce RBC
Which type of anemia is characterized by the destruction of red blood cells?
hemolytic anemia
iron-deficiency anemia
aplastic anemia
sickle cell anemia
What is the treatment for iron-deficiency anemia?
Blood transfusion and exercise
Iron supplementation and dietary changes
Vitamin C supplementation and rest
Antibiotics and surgery
Which type of anemia is caused by a lack of intrinsic factor?
pernicious anemia
sickle cell anemia
iron-deficiency anemia
aplastic anemia
What is the main symptom of anemia?
Dizziness
Fatigue or tiredness
Nausea
Fever
Which type of anemia is characterized by a decrease in all three types of blood cells?
aplastic anemia
iron-deficiency anemia
sickle cell anemia
pernicious anemia
Iron is stored in the form of ?
Transferin
Ferritin
Biliverdin
Protoporphyrin
Which of the following parameter is increased in IDA?
Serum Iron
Transferrin saturation
Serum ferritin
Free erythrocyte protoporphyrin
What is the most common cause of Iron Deficiency Anemia?
Vitamin B12 deficiency
Chronic blood loss
Excess iron intake
Bone marrow
Which of the following is not a common symptoms of Iron Deficiency Anemia?
Fatigue
Shortness of breath
Yellowing of skin
Brittle nails
What laboratory finding is most characteristic of Iron Deficiency Anemia?
High hemoglobin
Low ferritin level
High mean corpuscular volume (MCV)
High serum iron
Which of the following populations is at the highest risk of developing Iron Deficiency Anemia?
Post menopausal women
Young men
Pregnant women
Middle-aged men
Which vitamin enhances iron absorption?
Vitamin D
Vitamin C
Vitamin A
Vitamin K
Which of the following foods is the best for treating Iron Deficiency Anemia?
White rice
Red meat
Dairy products
Green tea
Which of the following conditions can lead to iron malabsorption?
Hypertension
Migraine
Celiac disease
Osteoarthritis
Which of the following blood test findings is commonly seen in Iron Deficiency Anemia?
Increased MCV
Increased serum ferritin
Increased serum iron
Increased TIBC
A craving for non nutritive substances like ice, clay or dirt is known as :
Glossitis
Koilonychia
Pica
Hemochromatosis
In Iron Deficiency Anemia, red blood cells typically appear :
Microcytic and hypochromic
Normochromic and normocytic
Macrocytic and normochromic
Spherocytic and hyperchromic
Which of the following is a key substance required for the incorporation of vitamin B12 in the nuclear synthesis of red blood cells?
EPO
Transferrin
Intrinsic factor
Homocysteine
Evidence of a megaloblastic anemia includes:
Microcytic RBCs
Thrombocytosis
Decreased red cell precursors with other cell lines unaffected
Pancytopenia
All of the following are possible causes of low levels of intrinsic factor (IF) except :
Gastrectomy
Pernicious anemia
Gastritis
Kidney failure
Which MCV range is indicative of pernicious anemia?
70 -80
85 - 95
95-105
110-120
Which of the following RBC morphologies is classic in the megaloblastic anemias?
Polychromasia
Macro ovalocytes
Macrocytes
Hypochromia
A macrocytosis that is not megaloblastic in origin can be have all of the following except:
Macrocytes
Pancytopenia
Decreased RBC count only
Hypersegmentation
Which of the following describes the ineffective erythropoiesis seen with megaloblastic anemia?
An increase in the M:E ratio
A synthetic defect in hemoglobin
Premature destruction of RBC precursors
A DNA maturation defect
Intrinsic factor is secreted by the:
Parietal cells
Ileum
Duodenum
Bone marrow
The Schilling test continues to be a historic reference method for the determination of:
IDA
Pernicious anemia
Folic acid deficiency
Non megaloblastic anemia
Macrocytic RBCs are routinely seen in all of the following except:
Pernicious anemia
Liver disease
Response to anemic stress
Thalassemia
Which of the following is a clinical symptom specific to B12 deficiency?
Fever
Numbness and trouble with balance
Pallor
Splenomegaly
All of the following may cause a non megaloblastic anemia except
Alcoholism
Pernicious anemia
Liver disease
Folate deficiency
What is the typical shape of red blood cells in Sickle Cell Anemia?
Donut Shaped
Cresent Shaped
Circular
Rectangular
How long do TYPICAL red blood cells take to break down and die?
A few hours
200 days
20 days
120 days
True or False: Sickle Cell Anemia can be diagnosed before birth.
True
False
Why are red blood cells important?
They aid in hydration
They fight off infections
They help deliver oxygen to the body
They destroy and break down cells
Which of the following is NOT something to specifically watch for in patients with sickle cell?
Symptoms of Stroke
Foot drop
Vision Problems
Swelling in hands and feet
Which of the following is a big concern regarding sickle cell anemia?
Nerve problems
Blood clots
Loss of Sensation
Which genotype represents a patient that suffers from sickle cell disease, if A represents the normal allele?
SS
AS
AA
SA
How many copies of the sickle cell gene are needed for a person to have the disorder?
0
1
2
3
Sickle cell is cause by
a virus
a parasite
a gene (DNA)
excessive cell phone use
Dr. Allison found that people with sickle cell anemia were more common (check all that apply)
in large cities
near the ocean
near lakes
in the mountains
The sickle-shaped cells can also stick to vessel walls, causing a blockage that slows or stops the flow of blood. When this happens, oxygen can't reach nearby tissues. The lack of oxygen can cause ______.
Anemia
Sickle Cell Anemia
Sickle Cell Trait
Episodes of Pain
Red Blood Cells
The sickle-shaped cells can also ______ vessel walls, causing a blockage that slows or stops the flow of blood. When this happens, _____ can't reach nearby tissues.
stick to, oxygen
scrape, oxygen
burst through, carbon dioxide
scrape, carbon dioxide
stick to, carbon oxygen
Who is at risk for sickle cell disease?
African Americans
Hispanics
Asians
Native Americans
Caucasians
What is the primary cause of sickle cell anemia?
A mutation in the hemoglobin gene
A deficiency in iron
A viral infection
An autoimmune disorder
Which of the following best describes the shape of red blood cells in sickle cell anemia?
Round
Oval
Sickle-shaped
Square
What is the main symptom of sickle cell anemia?
High blood pressure
Chronic pain
Excessive bleeding
Frequent infections
How is sickle cell anemia inherited?
Through a dominant allele
Through a recessive allele
Through a viral infection
Through environmental factors
Which population is most commonly affected by sickle cell anemia?
Caucasians
African Americans
Asians
Native Americans
What is the role of hemoglobin in red blood cells?
To carry oxygen
To fight infections
To clot blood
To produce energy
Which of the following treatments is commonly used for sickle cell anemia?
Antibiotics
Blood transfusions
Chemotherapy
Radiation therapy
What complication can arise from sickle cell anemia due to blocked blood vessels?
Stroke
Diabetes
Hypertension
Asthma
