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Cell Cycle & Cancer

Total questions: 56

Worksheet time: 48mins

Name
Class
Date
1.

The correct sequence of mitosis:

a)

metaphase, anaphase, telophase, prophase

b)

prophase, metaphase, anaphase, telophase

c)

prophase, anaphase, metaphase, telophase

d)

telophase, metaphase, prophase, anaphase

2.

Identical halves of a chromosome are called?

a)

Cousins

b)

Chromatids

c)

Centromere

d)

Centrosome

3.

Chromosomes are visible and spindle fibers start to appear

a)

prophase

b)

metaphase

c)

telophase

d)

anaphase

4.

Sister Chromatids separate from each other

a)

prophase

b)

telophase

c)

anaphase

d)

metaphase

5.

Chromosomes line along the center of the cell

a)

anaphase

b)

prophase

c)

metaphase

d)

telophase

6.

There are 2 nucli in one cell

a)

telophase

b)

prophase

c)

anaphase

d)

metaphase

7.

After mitosis the number of chromosomes in the newly created cells will be:

a)

Half the number of the original cell

b)

The same number as the original cell

c)

Twice as much as the original cell

8.

The division of the cytoplasm is called?

a)

anaphase

b)

mitosis

c)

cytokineses

d)

G0

9.

What type of cell will form a cell plate during mitosis?

a)

Haploid cells

b)

Plant Cells

c)

Animal Cells

d)

Diploid Cells

10.

Non dividing state of the cell cycle

a)

Interphase

b)

Mitosis

c)

Telophase

d)

Cytokinesis

11.

Uncontrolled growth can result in:

a)

G0 phase

b)

S phase

c)

Replication

d)

Cancer

12.
During which phase of the cell cycle does the cell spend the most time?
a)
Mitosis
b)
Cytokinesis
c)
Interphase
13.
During which part of the cell cycle does the cell divide?
a)
Interphase
b)
Mitosis
c)
S phase
14.
During which part of the cell cycle is DNA copied?
a)
Mitosis
b)
Cytokinesis
c)
S phase
15.
Which phase of mitosis is shown in the picture?
a)
Prophase
b)
Anaphase
c)
Telophase
16.
Which phase of mitosis is shown in the picture?
a)
Interphase
b)
Metaphase
c)
Telophase
17.
Which phase of mitosis is shown in the picture?
a)
Prophase
b)
Metaphase
c)
Anaphase
18.
Which phase of mitosis is shown in the picture?
a)
Prophase
b)
Telophase
c)
Metaphase
19.
What is the purpose of the cell cycle?
a)
To create new daughter cells
b)
To prevent cancer from developing
c)
To help the body fight viruses and bacteria
20.

Uncontrolled cell division which usually leads to tumors and disease is called:

a)

Metaphase

b)

Cytokinesis

c)

Cancer

d)

Diabetes

21.

The first phase of mitosis is called _______________ .

a)

telophase

b)

metaphase

c)

anaphase

d)

prophase

22.

Which is NOT a phase of the cell cycle?

a)

Interphase

b)

Cytokinesis

c)

Mitosis

d)

Duplication

23.
In the S stage of interphase_______________
a)
the cell grows
b)
the nucleus divides
c)
the cell membrane divides
d)
the DNA is replicated
24.

Which type of cell divides most frequently?

a)

Liver cell

b)

Skin cell

c)

Blood cell

d)

Nerve cell

25.

Which of these cells never divides?

a)

Skin cell

b)

Liver cell

c)

Nerve cell

d)

Blood cell

26.
What does DNA Replication mean?
a)
DNA is made.
b)
DNA makes new cells. 
c)
DNA copies itself.
d)
DNA starts the cell cycle.
27.

Why do your cells divide?

a)

to make more cells so you can grow

b)

to replace cells that are old or damaged with new ones

c)

both answers are correct

28.
Before cells can divide, what must be copied?
a)
mitochondria
b)
cytoplasm
c)
DNA
d)
Cell Wall
29.

During this phase of the cell cycle, DNA is replicated or copied.

a)

G1 phase

b)

S phase

c)

G2 phase

d)

Mitosis

e)

Cytokinesis

30.

Why does a cell need to copy its DNA?

a)

to store extra copies of DNA in your liver

b)

to ensure that each new cell gets a copy of DNA

31.

Two identical chromosomes/copies of DNA are called sister chromatids, and they are held together by a molecule called a centromere, until they are ready to be separated during mitosis.

Identify the sister chromatids in the image shown.

a)

A

b)

B

32.

Look at the cell cycle phases. What happens during mitosis?

a)

carry out normal functions

b)

replicate/duplicate the DNA

c)

prepare for cell division

d)

divides the nucleus

e)

divide the cytoplasm

33.
Why would it be important to replicate DNA before a cell divides in mitosis or meiosis?
a)
In order for genetic information to be transferred into daughter cells.
b)
In order for the cell to be able to increase in size.
c)
In order for the DNA to be contained in the nucleus.
d)
In order for the cell to re-order the DNA sequencing in the new cells.
34.

This process is the programmed death of a cell

a)

stem cell

b)

regulation

c)

apoptosis

d)

cytocide

35.

These undifferentiated cells can become specialized cells after receiving a chemical signal.

a)

stem cells

b)

generic cells

c)

blank cells

d)

empty cells

36.
Cytokinesis is a phase of mitosis. 
a)
True
b)
False 
37.
What does NOT happen during interphase?
a)
growth
b)
DNA replication 
c)
obtaining nutrients
d)
cell divison
38.
Cells spend the majority of their lives in
a)
Interphase
b)
Mitosis
c)
Synthesis 
d)
Gap 2
39.
What is cytokinesis?
a)
This is when two cells merge together to make one giant cell.
b)
The stage where chromosomes migrate to the opposite ends of the cell. 
c)
The stage of the cell cycle where the rest of the cell divides after mitosis is complete.
d)
The stage in which DNA condenses into chromosomes.
40.
True or False:
Normal cells grow and divide continuously.
a)
True
b)
False
41.

During most of interphase, DNA is found in a relaxed form called

a)

chromosome

b)

centromere

c)

centriole

d)

chromatin

42.

During mitosis, DNA is found in the condensed form called a

a)

chromosome

b)

centromere

c)

centriole

d)

chromatin

43.

In telophase of mitosis, chromosomes

a)

form and the nuclear envelope disappears.

b)

are pulled toward opposite ends of the cell.

c)

chromosomes line up along the equator of the cell

d)

chromosomes begin to decondense and the two new nuclei begin to form.

44.

After mitosis, the cytoplasm and organelles are divided between the two new forming cells in a process called

a)

centriole

b)

chromatin

c)

cytokinesis

d)

centromere

45.

A(n) _____ is a stage in the eukaryotic cell cycle at which the cell examines internal and external cues and "decides" whether or not to move forward with division.

a)

checkpoint

b)

chromosome

c)

interphase

d)

tumor

46.

Checks for chromosome attachment to the spindle at the metaphase plate.

a)

G1 checkpoint

b)

G2 checkpoint

c)

Spindle checkpoint (M checkpoint)

d)

DNA polymerase

47.

Checks for DNA damage and DNA replication completeness.

a)

G1 checkpoint

b)

G2 checkpoint

c)

Spindle checkpoint

d)

DNA polymerase

48.

Undifferentiated cells that can become one or more specialized types of cell are called_________

a)

Stem Cells

b)

Somatic Cells

c)

Body Cells

d)

Zygotes

49.

Arrange the following levels of hierarchy from LARGEST to SMALLEST

a)

Organism, Organ, Tissue, Cell

b)

Cell, Tissue, Organ, Organism

c)

Organism, Cell, Tissue, Organ

d)

Tissue, Cell, Organ, Organism

50.

What is a gene?

a)

A section of DNA with instructions for making a protein

b)

A section of DNA with instructions for making a carbohydrate

c)

One nucleic acid chain that codes for DNA

d)

One protein chain that codes for DNA

51.

How many chromosomes are in each human body cell?

a)

46

b)

23

c)

1

d)

48

52.

How are the centromere and telomere different?

a)

The centromere is the center of the chromosome, the telomeres are the ends

b)

The centromere is at the ends of the chromosomes, the telomere is at the center

c)

The centromere is larger than the telomere

d)

The telomere is larger than the centromere

53.

Centrioles form _______ during Prophase

a)

Spindle Fibers

b)

Chromosomes

c)

Sister Chromatids

d)

Chromatin

54.

A sea otter has 38 chromosomes in their body (somatic) cells. When one somatic cell undergoes mitosis, how many chromosomes will a daughter cell have?

a)

19

b)

27

c)

38

d)

76

55.

Substances or radiation that is known to produce or promote cancer are called

a)

carcinogens

b)

kinases

c)

cyclins

d)

malignancies

56.

While in the womb, the webbed fingers of an embryo undergo programmed cell death, also known as ____________________.

a)

apoptosis

b)

cytokinesis

c)

carcinogen

d)

stem cells

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