NEW
Font size
WorksheetsAP Biology Replication
Total questions: 28
Worksheet time: 25mins
ATG TGA CAG
How do the leading and the lagging strands differ?
The leading strand is synthesized in the same direction as the movement of the replication fork, and the lagging strand is synthesized in the opposite direction.
The leading strand is synthesized at twice the rate of the lagging strand.
The leading strand is synthesized in short fragments that are ultimately stitched together, whereas the lagging strand is synthesized continuously.
The leading strand is synthesized by adding nucleotides to the 3' end of the growing strand, and the lagging strand is synthesized by adding nucleotides to the 5? end.
** A model of a process involving nucleic acids is shown in Figure 1. Which of the following best explains what process is represented in Figure 1 ?
New DNA strands are being synthesized in the 3' to 5' direction from their DNA templates.
New DNA strands are being synthesized in the 5' to 3' direction from their DNA templates.
A new RNA strand is being synthesized in the 3' to 5' end from its DNA template.
Two new RNA strands are being synthesized in both directions from their DNA templates.
** Figure 1 shows some relevant details of a model of how a deoxynucleotide, in this case dTMP, is added to a growing strand of DNA. The features of this model provide evidence for which explanation of why all growing strands are synthesized in a 5′ to 3′ direction?
The two strands need to be antiparallel to bond properly.
Thymine and adenine would not bond properly if the strand grew from 3′ to 5′.
The translation of mRNA occurs in the 5′ to 3′ direction; therefore, the growing DNA strand must also grow in the 5′ to 3′ direction.
The phosphate group, attached to the 5′ carbon of the dTMP, forms a covalent bond with the oxygen atom attached to the 3′ carbon of the growing strand.
** Figure 1 illustrates a model of the molecules involved in DNA replication and their placement relative to each other. Which of the following correctly explains where DNA
replication will begin on the strand oriented 5'→3', reading from left to right?
DNA replication will be randomly initiated along the unwound portion of the DNA strand since base pairing will occur.
DNA replication cannot occur since there is already RNA base pairing with the template strand.
DNA replication will be initiated immediately to the left of the RNA, since DNA polymerase requires an RNA primer.
DNA replication will be initiated at the site of the topoisomerase since that is where DNA begins to uncoil.
