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Deletion, Insertion, Replacement Mutation Practice

Total questions: 15

Worksheet time: 15mins

Name
Class
Date
1.

Normal-
GAG-CTC-GAC-AGA
Mutant
GAG CTC-CAC-AGA

a)

no mutation

b)

substitution

c)

insertion

d)

deletion

2.

A frameshift mutation can occur with either _________ or __________ mutations.

a)

Addition, division

b)

Deletion, substitution

c)

Addition, substitution

d)

Addition, deletion

3.

The bottom DNA sequence in the image has been altered by this type of mutation

a)

substitution

b)

insertion

c)

deletion

d)

translocation

4.

Why are insertion and deletion mutations so harmful?

a)

They change all of the codons from the mutation on down the line, which changes the amino acid sequence

b)

They insert things that an organism doesn't need.

c)

They often delete things that organisms need.

d)

Insertion and deletions are not any more harmful than substitution mutations.

5.

What are the three types of gene mutation?

a)

Insertion, Deletion, Subsitution

b)

Aberration, Deletion, Substitution

c)

Inversion, Duplication, Insertion

d)

Insertion, Duplication, Substitution

6.

In this type of point mutation, one base pair is lost

a)

substitution

b)

insertion

c)

deletion

d)

translocation

7.

In this type of point mutation, one extra base pair is inserted into a sequence of DNA

a)

substitution

b)

insertion

c)

deletion

d)

translocation

8.

The bottom DNA sequence in the image has been altered by this type of mutation

a)

substitution

b)

insertion

c)

deletion

d)

translocation

9.

when a portion of the DNA is shifted in one direction due to a deleition or insertion

a)

frameshift

b)

gene

c)

deletion

d)

substitution

10.

Which type of mutation involves the removal of a nucleotide from a DNA sequence?

a)

Substitution

b)

Insertion

c)

Deletion

d)

Duplication

11.

What is the result of an insertion mutation in a DNA sequence?

a)

A nucleotide is replaced with another

b)

A nucleotide is added to the sequence

c)

A nucleotide is removed from the sequence

d)

A segment of DNA is duplicated

12.

In a replacement mutation, what happens to the DNA sequence?

a)

A nucleotide is added

b)

A nucleotide is removed

c)

A nucleotide is replaced with another

d)

A segment of DNA is inverted

13.

Which of the following mutations is most likely to cause a frameshift?

a)

Substitution

b)

Insertion

c)

Deletion

d)

Translocation

14.

How does a deletion mutation affect the reading frame of a gene?

a)

It shifts the reading frame

b)

It duplicates the reading frame

c)

It inverts the reading frame

d)

It does not affect the reading frame

15.

Which mutation type is least likely to affect the protein function?

a)

Insertion

b)

Deletion

c)

Substitution

d)

Frameshift