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DNA Replication Quiz

Total questions: 49

Worksheet time: 2hrs 45mins

Name
Class
Date
1.

In the accompanying image, a nucleotide is indicated by the letter _____.

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2.

Which of these is a difference between a DNA and an RNA molecule?

a)

B

b)

A

c)

C

d)

D

3.

This is an image of a(n) _____.

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4.

The letter A indicates a _____.

a)

nucleic acid

b)

nucleotide

c)

thiol

d)

amino acid

e)

none of the above

5.

A nitrogenous base is indicated by the letter _____.

a)

nucleotide

b)

phosphate group

c)

sugar

d)

nitrogenous base

e)

none of the above

6.

You can tell that this is an image of a DNA nucleotide and not an RNA nucleotide because you see a _____.

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7.

Which of these nitrogenous bases is found in DNA but not in RNA?

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8.

Which of these is(are) pyrimidines?

a)

thymine

b)

cytosine

c)

uracil

d)

adenine

9.

In a nucleotide, the nitrogenous base is attached to the sugar's _____ carbon and the phosphate group is attached to the sugar's _____ carbon.

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10.

Nucleic acids are assembled in the _____ direction.

a)

1' ... 3'

b)

5' ... 3'

c)

1' ... 2'

d)

2' ... 3'

11.

In a DNA double helix an adenine of one strand always pairs with a(n) _____ of the complementary strand.

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12.

Which of the following investigators was (were) responsible for the discovery that in DNA from any species, the amount of adenine equals the amount of thymine, and the amount of guanine equals the amount of cytosine?

a)

Alfred Hershey and Martha Chase

b)

Oswald Avery, Maclyn McCarty, and Colin MacLeod

c)

Matthew Meselson and Franklin Stahl

d)

Erwin Chargaff

13.

Thymine makes up 28% of the nucleotides in a sample of DNA from an organism. Approximately what percentage of the nucleotides in this sample will be guanine?

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14.

Does the distribution of bases in sea urchin DNA and salmon DNA follow Chargaff’s rules?

a)

Yes

b)

No

15.

What is the %T in wheat DNA?

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16.

If Chargaff’s equivalence rule is valid, then hypothetically we could extrapolate this to the combined genomes of all species on Earth. Do Chargaff’s equivalence rules still hold true when you consider those six species together?

a)

Yes

b)

No

17.

Short segments of newly synthesized DNA are joined into a continuous strand by _____.

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18.

After DNA replication is completed, _____.

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19.

The first step in the replication of DNA is catalyzed by _____.

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20.

The action of helicase creates _____.

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21.

Why is the new DNA strand complementary to the 3' to 5' strands assembled in short segments?

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22.

Is the new DNA strand complementary to the 3' to 5' strands assembled in short segments?

a)

each new DNA double helix consists of two new strands

b)

there are four double helices

c)

one DNA double helix consists of two old strands and one DNA double helix consists of two new strands

d)

each of the four DNA strands consists of some old strand parts and some new strand parts

e)

each new DNA double helix consists of one old DNA strand and one new DNA strand

23.

The synthesis of a new strand begins with the synthesis of a(n) (a)  

24.

Which of these is responsible for catalyzing the formation of an RNA primer?

a)

DNA polymerase can assemble DNA only in the 3' to 5' direction

b)

it is more efficient than assembling complete new strands

c)

RNA primer complementary to a preexisting DNA strand

d)

DNA polymerase can assemble DNA only in the 5' to 3' direction

e)

only short DNA sequences can extend off the RNA primers

25.

An old DNA strand is used as a (a)   for the assembly of a new DNA strand.

26.

What catalyzes DNA synthesis?

a)

source of nucleotides

b)

template

c)

model

d)

complement

e)

primer

27.

Which of the following statements about DNA synthesis is true?

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28.

Which part of a deoxynucleoside triphosphate (dNTP) molecule provides the energy for DNA synthesis?

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29.

Which of the following enzymes creates a primer for DNA polymerase?

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30.

Which of the following statements about Okazaki fragments in E. coli is true?

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31.

Which of the following enzymes is important for relieving the tension in a helix as it unwinds during DNA synthesis?

(a)  

32.

True or false? Single-stranded DNA molecules are said to be antiparallel when they are lined up next to each other but oriented in opposite directions.

a)

True

b)

False

33.

Which of the following statements accurately describes the differences between DNA replication in prokaryotes and DNA replication in eukaryotes?

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34.

In E. coli, there is a mutation in a gene called dnaB that alters the helicase that normally acts at the origin of replication. Which of the following events would you expect to occur as a result of this mutation?

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35.

Which of the following characteristics of eukaryotic telomeres cause them to replicate differently than the rest of the chromosome?

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36.

Which of the following statements correctly describes the difference between the leading and the lagging strands of DNA during DNA replication?

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37.

Why does a new DNA strand elongate only in the 5' to 3' direction during DNA replication?

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38.

What is the function of the enzyme topoisomerase in DNA replication?

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39.

What is the role of DNA ligase in the elongation of the lagging strand during DNA replication?

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40.

Which of the following types of molecules help to hold the DNA strands apart while they are being replicated?

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41.

Individuals with the disorder xeroderma pigmentosum are hypersensitive to sunlight, and mutations to the DNA in their skin cells are left uncorrected. Why are the mutations not corrected in individuals with this disorder?

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42.

Within a double-stranded DNA molecule, adenine forms hydrogen bonds with thymine, and cytosine forms hydrogen bonds with guanine. What is the significance of the structural arrangement?

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43.

In DNA replication, the resulting daughter molecules contain one strand of the original parental DNA and one new strand. What is the explanation for this phenomenon?

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44.

Which of the following statements correctly describes the difference between the leading strand and the lagging strand in DNA replication?

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45.

Telomere shortening puts a limit on the number of times a cell can divide. Research has shown that telomerase can extend the life span of cultured human cells. How?

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46.

How might adding telomerase affect cellular aging?

a)

Telomerase will speed up the rate of cell proliferation.

b)

Telomerase eliminates telomere shortening and retards aging.

c)

Telomerase shortens telomeres, which delays cellular aging.

d)

Telomerase would have no effect on cellular aging.

47.

Which of the following choices describes the function of DNA polymerase?

a)

Opens up double-stranded DNA to make it single stranded

b)

Cuts DNA segments into pieces of one or two nucleotides

c)

Catalyzes the linking of dATP, dCTP, dGTP, and dTTP in a specific order, using single-stranded DNA as a template

d)

Fuses intermediate-length DNA segments into longer segments

48.

What is the mechanism by which DNA is replicated?

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49.

How can you know if the person or organization providing the information has the credentials and knowledge to speak on this topic?

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