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Topic 13: Coenzymes Decarboxylation

Total questions: 10

Worksheet time: 6mins

Name
Class
Date
1.

Which coenzyme is involved in the non-oxidative decarboxylation of α-keto carboxylates?

a)

Thiamin Pyrophosphate (TPP)

b)

Pyridoxal Phosphate

c)

Biotin

d)

Coenzyme A

2.

What type of reaction is associated with Pyridoxal Phosphate?

a)

Methylation

b)

Phosphorylation

c)

Decarboxylation

d)

Hydroxylation

3.

Which reaction is NOT associated with Thiamin Pyrophosphate (TPP)?

a)

Retro-aldol condensation

b)

Racemization

c)

Non-oxidative decarboxylation

d)

Oxidative decarboxylation

4.

Which of the following is a reaction type associated with Thiamin Pyrophosphate (TPP)?

a)

Hydration

b)

Carboxylation

c)

Retro-aldol and aldol condensations

d)

Transamination

5.

Which coenzyme is primarily involved in transamination reactions?

a)

Pyridoxal Phosphate

b)

Thiamin Pyrophosphate (TPP)

c)

Coenzyme A

d)

Biotin

6.

What type of reaction is NOT typically associated with Pyridoxal Phosphate?

a)

Racemization

b)

Transamination

c)

Decarboxylation

d)

Carboxylation

7.

Which of the following vitamins is a cofactor for the enzyme responsible for the carboxylation of pyruvate to form oxaloacetate?

a)

Pantothenic acid (B5)

b)

Niacin (B3)

c)

Thiamine (B1)

d)

Riboflavin (B2)

8.

Lipoic acid is a coenzyme for:

a)

pyruvate hydroxylase

b)

pyruvate carboxylase

c)

pyruvate dehydrogenase

d)

alpha-ketoglutarate dehydrogenase

e)

citrate lyase

9.

Which of the following reactions involves the coenzyme Thiamin Pyrophosphate (TPP)?

a)

non-oxidative decarboxylation

of α-keto carboxylates

b)

oxidative decarboxylation

c)

decarboxylation of amino acids

d)

retro aldol and aldol

condensations

10.

Select the incorrect structure which is not part of the transimination mechanism catalyzed by pyridoxal phosphate (may not be shown in the correct order).

a)

b)

c)

d)

e)