Which one of the following statements best describes the molecular mechanism underlying the antiepileptic effects of carbamazepine and phenytoin?

Which antiepileptic agent gained wider therapeutic use also to treat trigeminal neuralgia and the manic phase of bipolar disorder?

Which one of the following agents is considered the drug of choice for initial treatment of generalized absence seizure (petit mal) in children?

Topiramate has which set of three mechanisms of action?

A 9-year-old child is having learning difficulties at school. He has brief lapses of awareness with eyelid fluttering that occur every 5-10 min. Electroencephalogram (EEG) studies reveal brief 3-Hz spike and wave discharges appearing synchronously in all leads. Which drug would be effective in this child without the disadvantages of excessive sedation or tolerance development?

Which drug used in management of seizure disorders is most likely to elevate the plasma concentration of other drugs administered concomitantly?

With chronic use in seizure states, the adverse effects of this drug include coarsening of facial features, hirsutism, and gingival hyperplasia.

A pregnant woman with primary generalized tonicclonic seizures, well controlled on Phenobarbital, stops taking her antiepileptic medication 4 months into her pregnancy. Which of the following best describes her decision?

A young male patient suffers from a seizure disorder characterised by tonic rigidity of the extremities, followed in 15–30 seconds by tremor progressing to massive jerking of the body. This clonic phase lasts for 1 or 2 minutes, leaving the patient in a stuporous state. Of the following drugs, which is most suitable for long-term management of this patient?

Which is the drug of choice for the treatment of juvenile myoclonic epilepsy in pregnancy?

Fetal hydantoin syndrome is seen if one of the following drugs is used in pregnancy.

The drug of choice for prevention of seizures in a patient with severe preeclampsia is:

First-line drug that has the best efficacy to be used in absence seizures is:

Prolonged use of one of the following anticonvulsant drugs can produce weight loss:

Status epilepticus is managed best with the use of which of the following drugs?

Raju, a 10-year-old boy, is having difficulty learning at school. He has short lapses of awareness with eyelid fluttering that occur every 5-10 minutes. EEG studies reveal brief 3 Hz spike and wave discharges appearing synchronously in all the leads. Which of the following drugs would be effective but has the disadvantage that it causes sedation and tolerance?

 An antiepileptic drug ‘A’ can also be used for the treatment of post-herpetic neuralgia and pain due to diabetic neuropathy. Which of the following can be the agent ‘A’?

Which of the following would you like to give to a pregnant patient to decrease the risk of neural tube defects in the offspring, if your patient is receiving antiepileptic drugs?

The antiepileptic drug which does not produce enzyme induction is: