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Cell BRS.

Total questions: 183

Worksheet time: 2hrs 32mins

Name
Class
Date
1.

Họ và tên:

4 lines
2.

Mã lớp học phần:

4 lines
3.

Q: Which of the following characteristics is shared by simple and facilitated diffusion of glucose?

A: Is saturable

a)

True

b)

False

4.

Q: Which of the following characteristics is shared by simple and facilitated diffusion of glucose?

A: Requires metabolic energy

a)

False

b)

True

5.

Q: Which of the following characteristics is shared by simple and facilitated diffusion of glucose?

A: Occurs down an electrochemical gradient

a)

True

b)

False

6.

Q: Which of the following characteristics is shared by simple and facilitated diffusion of glucose?

A: Is inhibited by pre sence of galactose

a)

False

b)

True

7.

Q: Which of the following characteristics is shared by simple and facilitated diffusion of glucose?

A: Requires a Na+ gradient

a)

True

b)

False

8.

Q: During the upstroke of nerve action potential

A: there is net outward current and the cell interior becomes more negative

a)

True

b)

False

9.

Q: During the upstroke of nerve action potential

A: there is net outward current and the cell interior becomes less negative

a)

False

b)

True

10.

Q: During the upstroke of nerve action potential

A: there is net inward current and the cell interior becomes more negative

a)

True

b)

False

11.

Q: During the upstroke of nerve action potential

A: there is net inward current and the cell interior becomes less negative

a)

False

b)

True

12.

Q: Solution A and B are seperated by a semipermeable membrane that is permeable to K+ but not Cl-. Solution A is 100 mM KCl, and solution B is 1 mM KCl. Which of the following statements about solution A and solution B is true?

A: K+ ions will diffuse from solution A to solution B until the [K+] of both solutions is 50.5 mM

a)

True

b)

False

13.

Q: Solution A and B are seperated by a semipermeable membrane that is permeable to K+ but not Cl-. Solution A is 100 mM KCl, and solution B is 1 mM KCl. Which of the following statements about solution A and solution B is true?

A: K+ ions will diffuse from solution B to solution A until the [K+] of both solutions is 50.5 mM

a)

True

b)

False

14.

Q: Solution A and B are seperated by a semipermeable membrane that is permeable to K+ but not Cl-. Solution A is 100 mM KCl, and solution B is 1 mM KCl. Which of the following statements about solution A and solution B is true?

A: KCl will diffuse from solution A to solution B until the [KCl] of both solutions is 50.5 mM

a)

True

b)

False

15.

Q: Solution A and B are seperated by a semipermeable membrane that is permeable to K+ but not Cl-. Solution A is 100 mM KCl, and solution B is 1 mM KCl. Which of the following statements about solution A and solution B is true?

A: K+ ions will diffuse from solution A to solution B until the membrane potential develops with solution A negative with respect to solution B

a)

True

b)

False

16.

Q: Solution A and B are seperated by a semipermeable membrane that is permeable to K+ but not Cl-. Solution A is 100 mM KCl, and solution B is 1 mM KCl. Which of the following statements about solution A and solution B is true?

A: K+ ions will diffuse from solution A to solution B until the membrane potential develops with solution A positive with respect to solution B

a)

True

b)

False

17.

Q: The correct temporal sequence for events at the neuromuscular junction is

A: action potential in motor nerve; depolarization of the muscle end plate; uptake of Ca2+ into the presynaptic nerve terminal

a)

True

b)

False

18.

Q: The correct temporal sequence for events at the neuromuscular junction is

A: uptake of Ca2+ into the presynaptic terminal; release of acetylcholin (ACh); depolarization of the muscle end plate

a)

True

b)

False

19.

Q: The correct temporal sequence for events at the neuromuscular junction is

A: release of ACh; action potential in motor nerve; action potential in the muscle

a)

True

b)

False

20.

Q: The correct temporal sequence for events at the neuromuscular junction is

A: uptake of Ca2+ into the motor end plate; action potential in the motor end plate; action potential in the muscle

a)

True

b)

False

21.

Q: The correct temporal sequence for events at the neuromuscular junction is

A: release of ACh; action potential in the muscle end plate; action potential in the muscle

a)

True

b)

False

22.

Q: Which characteristic or component is shared by skeletal muscle and smooth muscle?

A: Thick and thin filaments arranged in sarcomeres

a)

True

b)

False

23.

Q: Which characteristic or component is shared by skeletal muscle and smooth muscle?

A: Troponin

a)

True

b)

False

24.

Q: Which characteristic or component is shared by skeletal muscle and smooth muscle?

A: Elevation of intracellular [Ca2+] for excitation- contraction coupling

a)

True

b)

False

25.

Q: Which characteristic or component is shared by skeletal muscle and smooth muscle?

A: Spontaneous depolarization of the membrane potential

a)

True

b)

False

26.

Q: Which characteristic or component is shared by skeletal muscle and smooth muscle?

A: High degree of electrical coupling between cells

a)

True

b)

False

27.

Q: Repeated stimulation of a skeletal muscle fiber causes a sustained contraction (tetanus). Accumulation of which solute in intracellular fluid is responsible for the tetanus?

A: Na+

a)

True

b)

False

28.

Q: Repeated stimulation of a skeletal muscle fiber causes a sustained contraction (tetanus). Accumulation of which solute in intracellular fluid is responsible for the tetanus?

A: K+

a)

True

b)

False

29.

Q: Repeated stimulation of a skeletal muscle fiber causes a sustained contraction (tetanus). Accumulation of which solute in intracellular fluid is responsible for the tetanus?

A: Cl-

a)

True

b)

False

30.

Q: Repeated stimulation of a skeletal muscle fiber causes a sustained contraction (tetanus). Accumulation of which solute in intracellular fluid is responsible for the tetanus?

A: Mg2+

a)

True

b)

Fasle

31.

Q: Repeated stimulation of a skeletal muscle fiber causes a sustained contraction (tetanus). Accumulation of which solute in intracellular fluid is responsible for the tetanus?

A: Ca2+

a)

True

b)

False

32.

Q: Repeated stimulation of a skeletal muscle fiber causes a sustained contraction (tetanus). Accumulation of which solute in intracellular fluid is responsible for the tetanus?

A: Troponin

a)

True

b)

False

33.

Q: Repeated stimulation of a skeletal muscle fiber causes a sustained contraction (tetanus). Accumulation of which solute in intracellular fluid is responsible for the tetanus?

A: Calmodulin

a)

True

b)

False

34.

Q: Repeated stimulation of a skeletal muscle fiber causes a sustained contraction (tetanus). Accumulation of which solute in intracellular fluid is responsible for the tetanus?

A: Adenosine triphosphate (ATP)

a)

True

b)

False

35.

Q: Solutions A and B are separated by a membrane that is permeable to Ca2+ and impermeable to Cl-. Solution A contains 10 mM CaCl2. Assuming that 2.3 RT/F= 60mV, Ca2+ will be at electrochemical equilibrium when

A: solution A is +60 mV

a)

True

b)

False

36.

Q: Solutions A and B are separated by a membrane that is permeable to Ca2+ and impermeable to Cl-. Solution A contains 10 mM CaCl2. Assuming that 2.3 RT/F= 60mV, Ca2+ will be at electrochemical equilibrium when

A: solution A is +30 mV

a)

True

b)

False

37.

Q: Solutions A and B are separated by a membrane that is permeable to Ca2+ and impermeable to Cl-. Solution A contains 10 mM CaCl2. Assuming that 2.3 RT/F= 60mV, Ca2+ will be at electrochemical equilibrium when

A: solution A is -60 mV

a)

True

b)

False

38.

Q: Solutions A and B are separated by a membrane that is permeable to Ca2+ and impermeable to Cl-. Solution A contains 10 mM CaCl2. Assuming that 2.3 RT/F= 60mV, Ca2+ will be at electrochemical equilibrium when

A: solution A is -30mV

a)

True

b)

False

39.

Q: Solutions A and B are separated by a membrane that is permeable to Ca2+ and impermeable to Cl-. Solution A contains 10 mM CaCl2. Assuming that 2.3 RT/F= 60mV, Ca2+ will be at electrochemical equilibrium when

A: solution A is +120 mV

a)

True

b)

False

40.

Q: Solutions A and B are separated by a membrane that is permeable to Ca2+ and impermeable to Cl-. Solution A contains 10 mM CaCl2. Assuming that 2.3 RT/F= 60mV, Ca2+ will be at electrochemical equilibrium when

A: solution A is -120 mV

a)

True

b)

False

41.

Q: Solutions A and B are separated by a membrane that is permeable to Ca2+ and impermeable to Cl-. Solution A contains 10 mM CaCl2. Assuming that 2.3 RT/F= 60mV, Ca2+ will be at electrochemical equilibrium when

A: the Ca2+ concentrations of the two solutions are equal

a)

True

b)

False

42.

Q: Solutions A and B are separated by a membrane that is permeable to Ca2+ and impermeable to Cl-. Solution A contains 10 mM CaCl2. Assuming that 2.3 RT/F= 60mV, Ca2+ will be at electrochemical equilibrium when

A: the concentrations of the two solutions are equal

a)

True

b)

False

43.

Q: A 42-year-old man with myasthenia gravis notes increased muscle strength when he is treated with an acetylcholinesterase (AChE) inhibitor. The basis for his improvement is increased

A: amount of ACh released from motor nerves

a)

True

b)

False

44.

Q: A 42-year-old man with myasthenia gravis notes increased muscle strength when he is treated with an acetylcholinesterase (AChE) inhibitor. The basis for his improvement is increased

A: levels of ACh at the muscle end plates

a)

True

b)

False

45.

Q: A 42-year-old man with myasthenia gravis notes increased muscle strength when he is treated with an acetylcholinesterase (AChE) inhibitor. The basis for his improvement is increased

A: number of ACh receptors on the muscle end plates

a)

True

b)

False

46.

Q: A 42-year-old man with myasthenia gravis notes increased muscle strength when he is treated with an acetylcholinesterase (AChE) inhibitor. The basis for his improvement is increased

A: amount of norepinephrine released from motor nerves

a)

True

b)

False

47.

Q: A 42-year-old man with myasthenia gravis notes increased muscle strength when he is treated with an acetylcholinesterase (AChE) inhibitor. The basis for his improvement is increased

A: synthesis of norepinephrine in motor nerves

a)

True

b)

False

48.

Q: In a hospital error, a 60-year-old woman is infused with large volumes of a solution that causes lysis of her red blood cells (RBCs). The solution was most likely

A: 150 mM NaCl

a)

True

b)

False

49.

Q: In a hospital error, a 60-year-old woman is infused with large volumes of a solution that causes lysis of her red blood cells (RBCs). The solution was most likely

A: 300 mM mannitol

a)

True

b)

False

50.

Q: In a hospital error, a 60-year-old woman is infused with large volumes of a solution that causes lysis of her red blood cells (RBCs). The solution was most likely

A: 350 mM mannitol

a)

True

b)

False

51.

Q: In a hospital error, a 60-year-old woman is infused with large volumes of a solution that causes lysis of her red blood cells (RBCs). The solution was most likely

A: 300 mM urea

a)

True

b)

False

52.

Q: In a hospital error, a 60-year-old woman is infused with large volumes of a solution that causes lysis of her red blood cells (RBCs). The solution was most likely

A: 150 mM CaCl2

a)

True

b)

False

53.

Q: During a nerve action potential, a stimulus is delivered as indicated by the arrow shown in the following figure. In response to the stimulus, a second action potential

A: of smaller magnitude will occur

a)

True

b)

False

54.

Q: During a nerve action potential, a stimulus is delivered as indicated by the arrow shown in the following figure. In response to the stimulus, a second action potential

A: of normal magnitude will occur

a)

True

b)

False

55.

Q: During a nerve action potential, a stimulus is delivered as indicated by the arrow shown in the following figure. In response to the stimulus, a second action potential

A: of normal magnitude will occur but will be delayed

a)

True

b)

False

56.

Q: During a nerve action potential, a stimulus is delivered as indicated by the arrow shown in the following figure. In response to the stimulus, a second action potential

A: will occur but will not have an overshoot

a)

True

b)

False

57.

Q: During a nerve action potential, a stimulus is delivered as indicated by the arrow shown in the following figure. In response to the stimulus, a second action potential

A: will not occur

a)

True

b)

False

58.

Q: Solutions A and B are separated by a membrane that is permeable to urea. Solution A is 10 mM urea, and solution B is 5 mM urea. If the concentration of urea in solution A is doubled, the flux of urea across the membrane will

A: double

a)

True

b)

False

59.

Q: Solutions A and B are separated by a membrane that is permeable to urea. Solution A is 10 mM urea, and solution B is 5 mM urea. If the concentration of urea in solution A is doubled, the flux of urea across the membrane will

A: triple

a)

True

b)

False

60.

Q: Solutions A and B are separated by a membrane that is permeable to urea. Solution A is 10 mM urea, and solution B is 5 mM urea. If the concentration of urea in solution A is doubled, the flux of urea across the membrane will

A: be unchanged

a)

True

b)

False

61.

Q: Solutions A and B are separated by a membrane that is permeable to urea. Solution A is 10 mM urea, and solution B is 5 mM urea. If the concentration of urea in solution A is doubled, the flux of urea across the membrane will

A: decrease to one-half

a)

True

b)

False

62.

Q: Solutions A and B are separated by a membrane that is permeable to urea. Solution A is 10 mM urea, and solution B is 5 mM urea. If the concentration of urea in solution A is doubled, the flux of urea across the membrane will

A: decrease to one-third

a)

True

b)

False

63.

Q: A muscle cell has an intracellular [Na+] of 14 mM and an extracellular [Na+] of 140 mM. Assuming that 2.3 RT/F = 60 mV, what would the membrane potential be if the muscle cell membrane were permeable only to Na+?

(A) 80 mV

a)

True

b)

False

64.

Q: A muscle cell has an intracellular [Na+] of 14 mM and an extracellular [Na+] of 140 mM. Assuming that 2.3 RT/F = 60 mV, what would the membrane potential be if the muscle cell membrane were permeable only to Na+?

(A) −60 mV

a)

True

b)

False

65.

Q: A muscle cell has an intracellular [Na+] of 14 mM and an extracellular [Na+] of 140 mM. Assuming that 2.3 RT/F = 60 mV, what would the membrane potential be if the muscle cell membrane were permeable only to Na+?

(A) 0 mV

a)

True

b)

False

66.

Q: A muscle cell has an intracellular [Na+] of 14 mM and an extracellular [Na+] of 140 mM. Assuming that 2.3 RT/F = 60 mV, what would the membrane potential be if the muscle cell membrane were permeable only to Na+?

(A) +60 mV

a)

True

b)

False

67.

Q: A muscle cell has an intracellular [Na+] of 14 mM and an extracellular [Na+] of 140 mM. Assuming that 2.3 RT/F = 60 mV, what would the membrane potential be if the muscle cell membrane were permeable only to Na+?

(A) +80 mV

a)

True

b)

False

68.

Q: At which labeled point on the action potential is K+ closest to electrochemical equilibrium?

(A) 1

a)

True

b)

False

69.

Q: At which labeled point on the action potential is K+ closest to electrochemical equilibrium?

(A) 2

a)

True

b)

False

70.

Q: At which labeled point on the action potential is K+ closest to electrochemical equilibrium?

(A) 3

a)

True

b)

False

71.

Q: At which labeled point on the action potential is K+ closest to electrochemical equilibrium?

(A) 4

a)

True

b)

False

72.

Q: At which labeled point on the action potential is K+ closest to electrochemical equilibrium?

(A) 5

a)

True

b)

False

73.

Q: What process is responsible for the change in membrane potential that occurs between point 1 and point 3?

(A) Movement of Na+ into the cell

a)

True

b)

False

74.

Q: What process is responsible for the change in membrane potential that occurs between point 1 and point 3?

(A) Movement of Na+ out of the cell

a)

True

b)

False

75.

Q: What process is responsible for the change in membrane potential that occurs between point 1 and point 3?

(A) Movement of K+ into the cell

a)

True

b)

False

76.

Q: What process is responsible for the change in membrane potential that occurs between point 1 and point 3?

(A) Movement of K+ out of the cell

a)

True

b)

False

77.

Q: What process is responsible for the change in membrane potential that occurs between point 1 and point 3?

(A) Activation of the Na+–K+ pump

a)

True

b)

False

78.

Q: What process is responsible for the change in membrane potential that occurs between point 1 and point 3?

(A) Inhibition of the Na+–K+ pump

a)

True

b)

False

79.

Q: What process is responsible for the change in membrane potential that occurs between point 3 and point 4?

(A) Movement of Na+ into the cell

a)

True

b)

False

80.

Q: What process is responsible for the change in membrane potential that occurs between point 3 and point 4?

(A) Movement of Na+ out of the cell

a)

True

b)

False

81.

Q: What process is responsible for the change in membrane potential that occurs between point 3 and point 4?

(A) Movement of K+ into the cell

a)

True

b)

False

82.

Q: What process is responsible for the change in membrane potential that occurs between point 3 and point 4?

(A) Movement of K+ out of the cell

a)

True

b)

False

83.

Q: What process is responsible for the change in membrane potential that occurs between point 3 and point 4?

(A) Activation of the Na+–K+ pump

a)

True

b)

False

84.

Q: What process is responsible for the change in membrane potential that occurs between point 3 and point 4?

A: Inhibition of the Na+–K+ pump

a)

True

b)

False

85.

Q: The velocity of conduction of action potentials along a nerve will be increased by

(A) stimulating the Na+–K+ pump

a)

True

b)

False

86.

Q: The velocity of conduction of action potentials along a nerve will be increased by

(A) inhibiting the Na+–K+ pump

a)

True

b)

False

87.

Q: The velocity of conduction of action potentials along a nerve will be increased by

(A) decreasing the diameter of the nerve

a)

True

b)

False

88.

Q: The velocity of conduction of action potentials along a nerve will be increased by

(A) myelinating the nerve

a)

True

b)

False

89.

Q: The velocity of conduction of action potentials along a nerve will be increased by

(A) lengthening the nerve fiber

a)

True

b)

False

90.

Q: Solutions A and B are separated by a semipermeable membrane. Solution A contains 1 mM sucrose and 1 mM urea. Solution B contains 1 mM sucrose. The reflection coefficient for sucrose is one, and the reflection coefficient for urea is zero. Which of the following statements about these solutions is correct?

(A) Solution A has a higher effective osmotic pressure than solution B

a)

True

b)

False

91.

Q: Solutions A and B are separated by a semipermeable membrane. Solution A contains 1 mM sucrose and 1 mM urea. Solution B contains 1 mM sucrose. The reflection coefficient for sucrose is one, and the reflection coefficient for urea is zero. Which of the following statements about these solutions is correct?

(A) Solution A has a lower effective osmotic pressure than solution B

a)

True

b)

False

92.

Q: Solutions A and B are separated by a semipermeable membrane. Solution A contains 1 mM sucrose and 1 mM urea. Solution B contains 1 mM sucrose. The reflection coefficient for sucrose is one, and the reflection coefficient for urea is zero. Which of the following statements about these solutions is correct?

(A) Solutions A and B are isosmotic

a)

True

b)

False

93.

Q: Solutions A and B are separated by a semipermeable membrane. Solution A contains 1 mM sucrose and 1 mM urea. Solution B contains 1 mM sucrose. The reflection coefficient for sucrose is one, and the reflection coefficient for urea is zero. Which of the following statements about these solutions is correct?

(A) Solution A is hyperosmotic with respect to

solution B, and the solutions are isotonic

a)

True

b)

False

94.

Q: Solutions A and B are separated by a semipermeable membrane. Solution A contains 1 mM sucrose and 1 mM urea. Solution B contains 1 mM sucrose. The reflection coefficient for sucrose is one, and the reflection coefficient for urea is zero. Which of the following statements about these solutions is correct?

(A) Solution A is hyposmotic with respect to

solution B, and the solutions are isotonic

a)

True

b)

False

95.

Q: Transport of D- and L-glucose proceeds

at the same rate down an electrochemical gradient by which of the following processes?

(A) Simple diffusion

a)

True

b)

False

96.

Q: Transport of D- and L-glucose proceeds

at the same rate down an electrochemical gradient by which of the following processes?

(A) Facilitated diffusion

a)

True

b)

False

97.

Q: Transport of D- and L-glucose proceeds

at the same rate down an electrochemical gradient by which of the following processes?

(A) Primary active transport

a)

True

b)

False

98.

Q: Transport of D- and L-glucose proceeds

at the same rate down an electrochemical gradient by which of the following processes?

(A) Cotransport

a)

True

b)

False

99.

Q: Transport of D- and L-glucose proceeds

at the same rate down an electrochemical gradient by which of the following processes?

(A) Countertransport

a)

True

b)

False

100.

Q: Which of the following will double the

permeability of a solute in a lipid bilayer?

(A) Doubling the molecular radius of the solute

a)

True

b)

False

101.

Q: Which of the following will double the

permeability of a solute in a lipid bilayer?

(A) Doubling the oil/water partition coefficient of the solute

a)

True

b)

False

102.

Q: Which of the following will double the

permeability of a solute in a lipid bilayer?

(A) Doubling the thickness of the bilayer

a)

True

b)

False

103.

Q: Which of the following will double the

permeability of a solute in a lipid bilayer?

(A) Doubling the concentration difference of

the solute across the bilayer

a)

True

b)

False

104.

Q: A newly developed local anesthetic blocks Na+ channels in nerves. Which of the following effects on the action potential would it be expected to produce?

(A) Decrease the rate of rise of the upstroke of the action potential

a)

True

b)

False

105.

Q: A newly developed local anesthetic blocks Na+ channels in nerves. Which of the following effects on the action potential would it be expected to produce?

(A) Shorten the absolute refractory period

a)

True

b)

False

106.

Q: A newly developed local anesthetic blocks Na+ channels in nerves. Which of the following effects on the action potential would it be expected to produce?

(A) Abolish the hyperpolarizing

afterpotential

a)

True

b)

False

107.

Q: A newly developed local anesthetic blocks Na+ channels in nerves. Which of the following effects on the action potential would it be expected to produce?

(A) Increase the Na+ equilibrium potential

a)

True

b)

False

108.

Q: A newly developed local anesthetic blocks Na+ channels in nerves. Which of the following effects on the action potential would it be expected to produce?

(A) Decrease the Na+ equilibrium potential

a)

True

b)

False

109.

Q: At the muscle end plate, acetylcholine

(ACh) causes the opening of

(A) Na+ channels and depolarization toward the Na+ equilibrium potential

a)

True

b)

False

110.

Q: At the muscle end plate, acetylcholine

(ACh) causes the opening of

(A) K+ channels and depolarization toward the K+ equilibrium potential

a)

True

b)

False

111.

Q: At the muscle end plate, acetylcholine

(ACh) causes the opening of

(A) Ca2+ channels and depolarization toward the Ca2+ equilibrium potential

a)

True

b)

False

112.

Q: At the muscle end plate, acetylcholine

(ACh) causes the opening of

(A) Na+ and K+ channels and hyperpolarization to a value halfway between the Na+ and K+ equilibrium potentials

a)

True

b)

False

113.

Q: At the muscle end plate, acetylcholine

(ACh) causes the opening of

(A): Na+ and K+ channels and depolarization to a value halfway between the Na+ and K+ equilibrium potentials

a)

True

b)

False

114.

Q: An inhibitory postsynaptic potential

A: depolarizes the postsynaptic membrane by opening Na+ channels

a)

True

b)

False

115.

Q: An inhibitory postsynaptic potential

A: depolarizes the postsynaptic membrane by opening K+ channels

a)

True

b)

False

116.

Q: An inhibitory postsynaptic potential

A: hyperpolarizes the postsynaptic membrane by opening Ca2+ channels

a)

True

b)

False

117.

Q: An inhibitory postsynaptic potential

A: hyperpolarizes the postsynaptic membrane by opening Cl− channels

a)

True

b)

False

118.

Q: Which of the following would occur as a result of the inhibition of Na+, K+-ATPase?

A: Decreased intracellular Na+ concentration

a)

True

b)

False

119.

Q: Which of the following would occur as a result of the inhibition of Na+, K+-ATPase?

A: Increased intracellular K+ concentration

a)

True

b)

False

120.

Q: Which of the following would occur as a result of the inhibition of Na+, K+-ATPase?

A: Increased Na+–glucose cotransport

a)

True

b)

False

121.

Q: Which of the following would occur as a result of the inhibition of Na+, K+-ATPase?

A: Increased intracellular Ca2+ concentration

a)

True

b)

False

122.

Q: Which of the following would occur as a result of the inhibition of Na+, K+-ATPase?

A: Increased Na+–Ca2+ exchange

a)

True

b)

False

123.

Q: Which of the following temporal sequences is correct for excitation– contraction coupling in skeletal muscle?

A: Release of Ca2+ from the SR; depolarization of the T tubules; binding of Ca2+ to troponin C

a)

True

b)

False

124.

Q: Which of the following temporal sequences is correct for excitation– contraction coupling in skeletal muscle?

A: Action potential in the muscle membrane; splitting of adenosine triphosphate (ATP); binding of Ca2+ to troponin C

a)

True

b)

False

125.

Q: Which of the following temporal sequences is correct for excitation– contraction coupling in skeletal muscle?

A: Action potential in the muscle membrane; depolarization of the T tubules; release of Ca2+ from the sarcoplasmic reticulum (SR)

a)

True

b)

False

126.

Q: Which of the following temporal sequences is correct for excitation– contraction coupling in skeletal muscle?

A: Increased intracellular [Ca2+]; action potential in the muscle membrane; cross-bridge formation

a)

True

b)

False

127.

Q: Which of the following transport processes is involved if transport of glucose from the intestinal lumen into a small intestinal cell is inhibited by abolishing the usual Na+ gradient across the cell membrane?

A: Countertransport

a)

True

b)

False

128.

Q: Which of the following transport processes is involved if transport of glucose from the intestinal lumen into a small intestinal cell is inhibited by abolishing the usual Na+ gradient across the cell membrane?

A: Cotransport

a)

True

b)

False

129.

Q: Which of the following transport processes is involved if transport of glucose from the intestinal lumen into a small intestinal cell is inhibited by abolishing the usual Na+ gradient across the cell membrane?

A: Primary active transport

a)

True

b)

False

130.

Q: Which of the following transport processes is involved if transport of glucose from the intestinal lumen into a small intestinal cell is inhibited by abolishing the usual Na+ gradient across the cell membrane?

A: Facilitated diffusion

a)

True

b)

False

131.

Q: Which of the following transport processes is involved if transport of glucose from the intestinal lumen into a small intestinal cell is inhibited by abolishing the usual Na+ gradient across the cell membrane?

A: Simple diffusion

a)

True

b)

False

132.

Q: In skeletal muscle, which of the following events occurs before depolarization of the T tubules in the mechanism of excitation– contraction coupling?

A: Opening of Ca2+ release channels on the sarcoplasmic reticulum (SR)

a)

True

b)

False

133.

Q: In skeletal muscle, which of the following events occurs before depolarization of the T tubules in the mechanism of excitation– contraction coupling?

A: Uptake of Ca2+ into the SR by Ca2+- adenosine triphosphatase (ATPase)

a)

True

b)

False

134.

Q: In skeletal muscle, which of the following events occurs before depolarization of the T tubules in the mechanism of excitation– contraction coupling?

A: Binding of Ca2+ to troponin C

a)

True

b)

False

135.

Q: In skeletal muscle, which of the following events occurs before depolarization of the T tubules in the mechanism of excitation– contraction coupling?

A: Binding of actin and myosin

a)

True

b)

False

136.

Q: In skeletal muscle, which of the following events occurs before depolarization of the T tubules in the mechanism of excitation– contraction coupling?

A: Depolarization of the sarcolemmal membrane

a)

True

b)

False

137.

Q: Which of the following is an inhibitory neurotransmitter in the central nervous system (CNS)?

A: Glutamate

a)

True

b)

False

138.

Q: Which of the following is an inhibitory neurotransmitter in the central nervous system (CNS)?

A: γ-Aminobutyric acid (GABA)

a)

True

b)

False

139.

Q: Which of the following is an inhibitory neurotransmitter in the central nervous system (CNS)?

A: Serotonin

a)

True

b)

False

140.

Q: Which of the following is an inhibitory neurotransmitter in the central nervous system (CNS)?

A: Histamine

a)

True

b)

False

141.

Q: Which of the following is an inhibitory neurotransmitter in the central nervous system (CNS)?

A: Norepinephrine

a)

True

b)

False

142.

Q: Adenosine triphosphate (ATP) is used indirectly for which of the following processes?

A: Transport of K+ from extracellular to intracellular fluid

a)

True

b)

False

143.

Q: Adenosine triphosphate (ATP) is used indirectly for which of the following processes?

A: Transport of Na+ from intracellular to extracellular fluid

a)

True

b)

False

144.

Q: Adenosine triphosphate (ATP) is used indirectly for which of the following processes?

A: Transport of H+ from parietal cells into the lumen of the stomach

a)

True

b)

False

145.

Q: Adenosine triphosphate (ATP) is used indirectly for which of the following processes?

A: Absorption of glucose by intestinal epithelial cells

a)

True

b)

False

146.

Q: Adenosine triphosphate (ATP) is used indirectly for which of the following processes?

A: Accumulation of Ca2+ by the sarcoplasmic reticulum (SR)

a)

True

b)

False

147.

Q: Which of the following causes rigor in skeletal muscle?

A: An increase in intracellular Ca2+ level

a)

True

b)

False

148.

Q: Which of the following causes rigor in skeletal muscle?

A: A decrease in intracellular Ca2+ level

a)

True

b)

False

149.

Q: Which of the following causes rigor in skeletal muscle?

A: An increase in adenosine triphosphate

(ATP) level

a)

True

b)

False

150.

Q: Which of the following causes rigor in skeletal muscle?

A: A decrease in ATP level

a)

True

b)

False

151.

Q: Which of the following causes rigor in skeletal muscle?

A: Lack of action potentials in motoneurons

a)

True

b)

False

152.

Q: Degeneration of dopaminergic neurons has been implicated in

A: schizophrenia

a)

True

b)

False

153.

Q: Degeneration of dopaminergic neurons has been implicated in

A: Parkinson disease

a)

True

b)

False

154.

Q: Degeneration of dopaminergic neurons has been implicated in

A: myasthenia gravis

a)

True

b)

False

155.

Q: Degeneration of dopaminergic neurons has been implicated in

A: curare poisoning

a)

True

b)

False

156.

Q: Assuming complete dissociation of all solutes, which of the following solutions would be hyperosmotic to 1 mM NaCl?

A: 1 mM glucose

a)

True

b)

False

157.

Q: Assuming complete dissociation of all solutes, which of the following solutions would be hyperosmotic to 1 mM NaCl?

A: 1.5 mM glucose

a)

True

b)

False

158.

Q: Assuming complete dissociation of all solutes, which of the following solutions would be hyperosmotic to 1 mM NaCl?

A: 1 mM CaCl2

a)

True

b)

False

159.

Q: Assuming complete dissociation of all solutes, which of the following solutions would be hyperosmotic to 1 mM NaCl?

A: 1 mM sucrose

a)

True

b)

False

160.

Q: Assuming complete dissociation of all solutes, which of the following solutions would be hyperosmotic to 1 mM NaCl?

A: 1 mM KCl

a)

True

b)

False

161.

Q: A new drug is developed that blocks the transporter for H+ secretion in gastric parietal cells. Which of the following transport processes is being inhibited?

A: Countertransport

a)

True

b)

False

162.

Q: A new drug is developed that blocks the transporter for H+ secretion in gastric parietal cells. Which of the following transport processes is being inhibited?

A: Cotransport

a)

True

b)

False

163.

Q: A new drug is developed that blocks the transporter for H+ secretion in gastric parietal cells. Which of the following transport processes is being inhibited?

A: Primary active transport

a)

True

b)

False

164.

Q: A new drug is developed that blocks the transporter for H+ secretion in gastric parietal cells. Which of the following transport processes is being inhibited?

A: Facilitated diffusion

a)

True

b)

False

165.

Q: A new drug is developed that blocks the transporter for H+ secretion in gastric parietal cells. Which of the following transport processes is being inhibited?

A: Simple diffusion

a)

True

b)

False

166.

Q: A 56-year-old woman with severe muscle weakness is hospitalized. The only abnormality in her laboratory values is an elevated serum K+ concentration. The elevated serum K+ causes muscle weakness because

A: the resting membrane potential is hyperpolarized

a)

True

b)

False

167.

Q: A 56-year-old woman with severe muscle weakness is hospitalized. The only abnormality in her laboratory values is an elevated serum K+ concentration. The elevated serum K+ causes muscle weakness because

A: the K+ equilibrium potential is hyperpolarized

a)

True

b)

False

168.

Q: A 56-year-old woman with severe muscle weakness is hospitalized. The only abnormality in her laboratory values is an elevated serum K+ concentration. The elevated serum K+ causes muscle weakness because

A: the Na+ equilibrium potential is hyperpolarized

a)

True

b)

False

169.

Q: A 56-year-old woman with severe muscle weakness is hospitalized. The only abnormality in her laboratory values is an elevated serum K+ concentration. The elevated serum K+ causes muscle weakness because

A: K+ channels are closed by depolarization

a)

True

b)

False

170.

Q: A 56-year-old woman with severe muscle weakness is hospitalized. The only abnormality in her laboratory values is an elevated serum K+ concentration. The elevated serum K+ causes muscle weakness because

A: K+ channels are opened by

depolarization

a)

True

b)

False

171.

Q: A 56-year-old woman with severe muscle weakness is hospitalized. The only abnormality in her laboratory values is an elevated serum K+ concentration. The elevated serum K+ causes muscle weakness because

A: Na+ channels are closed by depolarization

a)

True

b)

False

172.

Q: A 56-year-old woman with severe muscle weakness is hospitalized. The only abnormality in her laboratory values is an elevated serum K+ concentration. The elevated serum K+ causes muscle weakness because

A: Na+channels are opened by depolarization

a)

True

b)

False

173.

Q: In contraction of gastrointestinal smooth muscle, which of the following events occurs after binding of Ca2+ to calmodulin?

A: Depolarization of the sarcolemmal membrane

a)

True

b)

False

174.

Q: In contraction of gastrointestinal smooth muscle, which of the following events occurs after binding of Ca2+ to calmodulin?

A: Ca2+-induced Ca2+ release

a)

True

b)

False

175.

Q: In contraction of gastrointestinal smooth muscle, which of the following events occurs after binding of Ca2+ to calmodulin?

A: Increased myosin-light-chain kinase

a)

True

b)

False

176.

Q: In contraction of gastrointestinal smooth muscle, which of the following events occurs after binding of Ca2+ to calmodulin?

A: Increased intracellular Ca2+ concentration

a)

True

b)

False

177.

Q: In contraction of gastrointestinal smooth muscle, which of the following events occurs after binding of Ca2+ to calmodulin?

A: Opening of ligand-gated Ca2+ channels

a)

True

b)

False

178.

Q: In an experimental preparation of a nerve axon, membrane potential (Em), K+ equilibrium potential, and K+ conductance can bemeasured.Whichcombinationofvalues will create the largest outward current flow?

A: (A)

a)

True

b)

False

179.

Q: In an experimental preparation of a nerve axon, membrane potential (Em), K+ equilibrium potential, and K+ conductance can bemeasured.Whichcombinationofvalues will create the largest outward current flow?

A: (B)

a)

True

b)

False

180.

Q: In an experimental preparation of a nerve axon, membrane potential (Em), K+ equilibrium potential, and K+ conductance can bemeasured.Whichcombinationofvalues will create the largest outward current flow?

A: (C)

a)

True

b)

False

181.

Q: In an experimental preparation of a nerve axon, membrane potential (Em), K+ equilibrium potential, and K+ conductance can bemeasured.Whichcombinationofvalues will create the largest outward current flow?

A: (D)

a)

True

b)

False

182.

Q: In an experimental preparation of a nerve axon, membrane potential (Em), K+ equilibrium potential, and K+ conductance can bemeasured.Whichcombinationofvalues will create the largest outward current flow?

A: (E)

a)

True

b)

False

183.

Q: In an experimental preparation of a nerve axon, membrane potential (Em), K+ equilibrium potential, and K+ conductance can bemeasured.Whichcombinationofvalues will create the largest outward current flow?

A: (F)

a)

True

b)

False