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WorksheetsGluconeogenesis and Glycogen Storage Quiz
Total questions: 20
Worksheet time: 10mins
Which of the following is a key enzyme of gluconeogenesis?
Hexokinase
Pyruvate kinase
Fructose-1,6-bisphosphatase
Phosphofructokinase-1
Fructose-1,6-bisphosphatase
Which enzyme converts pyruvate to oxaloacetate in gluconeogenesis?
PEP carboxykinase
Pyruvate carboxylase
Lactate dehydrogenase
Malate dehydrogenase
Which of these is NOT a substrate for gluconeogenesis?
Lactate
Glycerol
Alanine
Acetyl-CoA
Which cycle explains the transport of lactate from muscle to liver?
Urea cycle
Cori cycle
Malate-aspartate shuttle
Krebs cycle
How many ATP equivalents are required to form one glucose via gluconeogenesis?
2
4
6
8
Which enzyme bypasses the action of pyruvate kinase in gluconeogenesis?
Fructose-1,6-bisphosphatase
Pyruvate carboxylase
PEP carboxykinase
Hexokinase
What regulates gluconeogenesis positively?
Insulin
AMP
Glucagon
Fructose-2,6-bisphosphate
Which disaccharide is made of glucose and fructose?
Lactose
Maltose
Sucrose
Trehalose
Which enzyme digests lactose?
Sucrase
Lactase
Maltase
Isomaltase
Lactose is found in which of the following?
Honey
Fruits
Milk
Cereals
What is the main fate of acetyl-CoA in aerobic tissues?
Ketone body formation
Cholesterol synthesis
Entry into TCA cycle
Conversion to pyruvate
Which term describes TCA cycle’s role in both catabolism and anabolism?
Anabolic
Amphibolic
Anaplerotic
Reductive
Which is an example of anaplerotic reaction?
Citrate → Isocitrate
Pyruvate → Acetyl-CoA
Fumarate → Malate
Pyruvate → Oxaloacetate
Which coenzyme is required by pyruvate carboxylase?
Biotin
Thiamine
NAD+
FAD
Which intermediate links glycolysis to the TCA cycle?
Fructose-1,6-bisphosphate
Acetyl-CoA
Pyruvate
Glucose-6-phosphate
Which of the following defines glycogen storage disorders?
Disorders of lipid storage
Disorders affecting lysosomes
Disorders of carbohydrate digestion
Inherited enzyme defects of glycogen metabolism
Von Gierke’s disease is due to deficiency of:
Glucose-6-phosphatase
Glycogen phosphorylase
Branching enzyme
Debranching enzyme
Von Gierke’s disease leads to all EXCEPT:
Hypoglycemia
Hepatomegaly
Ketosis
Lactic acidosis
Which glycogen storage disease is due to muscle phosphorylase deficiency?
Pompe’s disease
Cori’s disease
McArdle’s disease
Andersen’s disease
Which of the following regulates gluconeogenesis negatively?
Glucagon
ATP
Citrate
AMP
