NEW
Font size
WorksheetsDystrophic and Metastatic Calcification Quiz
Total questions: 20
Worksheet time: 10mins
Dystrophic calcification occurs in:
Normal tissues with hypercalcemia
Necrotic or damaged tissues
Necrosis-free tissues
Only kidneys
Serum calcium levels in dystrophic calcification are:
High
Low
Normal
Variable
Classic site of dystrophic calcification:
Healthy kidney
Normal lung
Atherosclerotic plaques
Normal bone
Metastatic calcification occurs due to:
Normal calcium levels
Hypercalcemia only
Hypocalcemia
Local tissue damage only
Common site of metastatic calcification:
Heart valves
Atherosclerotic plaques
Old scars
Gastric mucosa
Most common cause of metastatic calcification:
Vitamin K deficiency
Hyperparathyroidism
Obesity
Viral infections
Psammoma bodies are seen in:
Tuberculosis
Lymphoma
Papillary carcinoma of thyroid
Multiple myeloma
Lipofuscin is a marker of:
Acute inflammation
Aging and wear-and-tear
Excess iron
Hyperbilirubinemia
Lipofuscin is derived from:
Protein oxidation
Lipid peroxidation
Calcium accumulation
Cholesterol deposits
Free radicals cause injury mainly by:
Protein synthesis
Lipid peroxidation and DNA damage
Increasing ATP
Increasing calcium efflux
Major enzyme for neutralizing hydrogen peroxide:
Lysozyme
Catalase
Elastase
Tyrosinase
Autophagy primarily involves:
Proteasomes
Mitochondria
Lysosomes
Ribosomes
Stain used for fat in frozen sections:
H&E
Sudan III
Masson trichrome
Periodic acid–Schiff
Hemosiderin is best identified by:
Ziehl–Neelsen stain
Gram stain
Prussian blue stain
Alcian blue
Intracellular accumulation of proteins appears as:
Clear vacuoles
Globular eosinophilic droplets
Granular black pigment
Basophilic inclusions
Melanin is synthesized from:
Tyrosine
Phenylalanine
Histidine
Tryptophan
Most potent reactive oxygen species (ROS):
Superoxide
H₂O₂
Hydroxyl radical
Nitric oxide
Main cause of anthracosis:
Iron overload
Carbon pigment inhalation
Bilirubin excess
Calcium deposition
Fatty change is most commonly seen in:
Kidney
Heart
Liver
Spleen
A hallmark of reversible cell injury:
Karyolysis
Membrane rupture
Hydropic change
Nuclear fragmentation
