WorksheetsDiuretics Quiz
Total questions: 25
Worksheet time: 13mins
Which diuretics have the highest efficacy in mobilizing sodium and water?
Thiazide diuretics
Potassium-sparing diuretics
Loop diuretics
Carbonic anhydrase inhibitors
Loop diuretics exert their main action by inhibiting which transporter?
Na⁺/Cl⁻ cotransporter
Na⁺/K⁺-ATPase
Na⁺/K⁺/2Cl⁻ cotransporter
Epithelial sodium channel (ENaC)
Which segment of the nephron is the primary site of action of thiazide diuretics?
Proximal convoluted tubule
Ascending loop of Henle
Distal convoluted tubule
Collecting tubule
Which diuretic decreases urinary calcium excretion?
Furosemide
Bumetanide
Hydrochlorothiazide
Ethacrynic acid
Which diuretic is most commonly associated with ototoxicity?
Hydrochlorothiazide
Spironolactone
Ethacrynic acid
Amiloride
Which diuretic is considered first-line therapy for hypertension?
Loop diuretics
Thiazide diuretics
Potassium-sparing diuretics
Osmotic diuretics
Thiazide diuretics reduce blood pressure mainly by:
Decreasing heart rate
Increasing cardiac output
Reducing peripheral vascular resistance
Causing venodilation
Which diuretic is preferred in acute pulmonary edema?
Hydrochlorothiazide
Spironolactone
Furosemide
Amiloride
Which effect occurs before diuresis with loop diuretics?
Arterial vasodilation
Venodilation
Increased aldosterone secretion
Decreased calcium excretion
Which adverse effect is most common with thiazide diuretics?
Hyperkalemia
Hypokalemia
Ototoxicity
Gynecomastia
Which diuretic is a thiazide-like diuretic?
Furosemide
Chlorthalidone
Spironolactone
Amiloride
Which diuretic is useful in patients with hypercalcemia?
Hydrochlorothiazide
Indapamide
Furosemide
Spironolactone
Which potassium-sparing diuretic works by blocking aldosterone receptors?
Amiloride
Triamterene
Spironolactone
Hydrochlorothiazide
Which potassium-sparing diuretic is more selective and causes fewer endocrine side effects?
Spironolactone
Amiloride
Triamterene
Eplerenone
Amiloride and triamterene act by blocking:
Na⁺/Cl⁻ cotransporter
Na⁺/K⁺/2Cl⁻ cotransporter
Aldosterone receptors
Epithelial sodium channels
Why are diuretics acting in the proximal tubule relatively weak?
Low sodium reabsorption
Poor oral bioavailability
Downstream nephron compensation
Increased potassium excretion
Which diuretic is the only thiazide available IV?
Hydrochlorothiazide
Chlorthalidone
Chlorothiazide
Indapamide
Which diuretic has unpredictable oral bioavailability?
Torsemide
Bumetanide
Furosemide
Chlorthalidone
Which adverse effect is shared by both thiazides and loop diuretics?
Hyperkalemia
Hypokalemia
Gynecomastia
Metabolic alkalosis only
Spironolactone is the diuretic of choice for ascites due to:
Heart failure
Renal failure
Hepatic cirrhosis
Hypertension
Which diuretic is commonly added to loop diuretics in resistant heart failure?
Indapamide
Metolazone
Amiloride
Eplerenone
Which diuretic may cause gynecomastia?
Eplerenone
Amiloride
Spironolactone
Triamterene
Which diuretic is most appropriate to prevent hypokalemia caused by thiazides?
Furosemide
Spironolactone
Indapamide
Ethacrynic acid
Which diuretics are least effective when used alone for edema or hypertension?
Loop diuretics
Thiazide diuretics
Potassium-sparing diuretics
Osmotic diuretics
Which diuretic may increase serum uric acid and precipitate gout?
Thiazides
Loop diuretics
Both A and B
Potassium-sparing diuretics
