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Fatty Acid Metabolism Quiz

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

What is the key enzyme in de novo synthesis of fatty acids?

a)

Fatty acid synthase

b)

Acetyl-CoA carboxylase

c)

Lipase

d)

HMG-CoA reductase

2.

Which coenzyme is required by acetyl-CoA carboxylase?

a)

NAD+

b)

Biotin

c)

FAD

d)

Thiamine

3.

The regulatory step in fatty acid synthesis is catalyzed by?

a)

Fatty acid synthase

b)

Acetyl-CoA carboxylase

c)

Lipase

d)

Malonyl-CoA reductase

4.

Citrate activates which enzyme?

a)

Fatty acid synthase

b)

Malonyl-CoA decarboxylase

c)

Acetyl-CoA carboxylase

d)

Lipase

5.

Which molecule is a precursor for malonyl-CoA?

a)

Palmitate

b)

Oxaloacetate

c)

Acetyl-CoA

d)

Acetoacetate

6.

NADPH used in fatty acid synthesis is mainly produced from?

a)

Glycolysis

b)

HMP shunt

c)

Krebs cycle

d)

Gluconeogenesis

7.

Fatty acid synthase complex is a?

a)

Single multifunctional polypeptide

b)

Separate enzymes

c)

Coenzyme

d)

Transport protein

8.

Product of de novo fatty acid synthesis is?

a)

Acetoacetate

b)

Palmitate

c)

Oleate

d)

Stearate

9.

Beta-oxidation of fatty acids occurs in the?

a)

Cytosol

b)

Nucleus

c)

Mitochondria

d)

Ribosome

10.

The initial activation of fatty acids occurs in the?

a)

Mitochondria

b)

ER

c)

Nucleus

d)

Cytosol

11.

Which molecule transports fatty acids into mitochondria?

a)

Acetyl-CoA

b)

Carnitine

c)

Coenzyme A

d)

Malonyl-CoA

12.

Enzyme responsible for transporting fatty acids into mitochondria?

a)

CPT I

b)

CPT II

c)

Thiokinase

d)

Enoyl hydratase

13.

Odd-chain fatty acid oxidation yields which final product?

a)

Pyruvate

b)

Malonyl-CoA

c)

Propionyl-CoA

d)

Lactate

14.

Propionyl-CoA enters the TCA cycle via?

a)

Succinyl-CoA

b)

Citrate

c)

Acetyl-CoA

d)

Fumarate

15.

Which vitamin is required for conversion of propionyl-CoA to succinyl-CoA?

a)

Biotin

b)

Riboflavin

c)

Niacin

d)

Thiamine

16.

How many ATPs are produced from complete oxidation of one palmitic acid?

a)

106

b)

38

c)

129

d)

78

17.

Which of the following inhibits CPT I?

a)

Acetyl-CoA

b)

NADH

c)

Malonyl-CoA

d)

FADH2

18.

What is the role of thiolase in beta-oxidation?

a)

Dehydration

b)

Hydration

c)

Cleavage of ketoacyl-CoA

d)

Oxidation of FADH2

19.

How many cycles of beta-oxidation are needed for palmitate?

a)

8

b)

7

c)

6

d)

9

20.

Which hormone stimulates lipolysis and beta-oxidation?

a)

Insulin

b)

Glucagon

c)

Epinephrine

d)

Thyroxine