NEW
Font size
WorksheetsScreening Round
Total questions: 20
Worksheet time: 15mins
Which of the following is a common cause of nephrotic syndrome in children?
Focal segmental glomerulosclerosis
Minimal change disease
Membranoproliferative glomerulonephritis
Membranous nephropathy
Which of the following molecular events best distinguishes apoptosis from necrosis?
Caspase activation
ATP depletion
Reactive oxygen species accumulation
Loss of membrane integrity
Which mediator is most responsible for the pain associated with acute inflammation?
Histamine
Prostaglandin E2
Bradykinin
Leukotriene B4
The Warburg effect in cancer cells is characterized by:
Preference for aerobic glycolysis
Increased oxidative phosphorylation
Enhanced fatty acid oxidation
Accumulation of ketone bodies
A deficiency of C1 esterase inhibitor leads to:
Hereditary angioedema
Paroxysmal nocturnal hemoglobinuria
Serum sickness
Hyper-IgE syndrome
Osteogenesis imperfecta also called “brittle bone disease,” is a group of genetic disorders caused by defective synthesis of
Type I collagen
Type II collagen
Type IV collagen
Type III collagen
Ringed Sideroblasts are seen in:
Iron deficiency anemia
Myelodysplastic syndrome
Thalassemia
Anemia of chronic disease
A liver biopsy in a child reveals periodic acid–Schiff (PAS)-positive, diastase-resistant globules in hepatocytes. What is the most likely diagnosis?
Reye Syndrome
Hemochromatosis
Alpha-1 Antitrypsin Deficiency
Wilson’s Disease
In the gene regulation mechanism, which of the following functions is NOT related to the long-noncoding RNA (lncRNA)?
Gene Activation
Translational repression
Promote chromatin modification
Assembly of protein complexes
Triad of late manifestation of congenital Syphilis are all EXCEPT
Interstital Keratitis
Hutchinson teeth
Tabes dorsalis
8th Nerve Deafness
Which of the following feature helps to differentiate intraductal papilloma from intraductal papillary carcinoma ?
The presence of a double-layered epithelium
Stromal over growth
Slit like spaces
Eosinophilic cytoplasm
Regarding Mucoepidermoid carcinoma which of the following statement is correct?
It is composed of mixture of squamous cells, mucus secreting cells and intermediate cells
It shows PLAG1 gene rearrangements
It is composed of cells which resemble normal serous acinar cells
It is composed of lymphoid stroma
Which of the following is characterized genetically by t(14;18)(q32;q21), translocation leading to fusion of the IGH and BCL2 genes?
Chronic lymphocytic leukemia (CLL) / small lymphocytic lymphoma
Mantle cell lymphoma
Hairy cell leukemia
Follicular lymphoma
Primary hyperparathyroidism, Pancreatic islet cell tumors and Prolactinomas are associated with which of the following syndrome?
Wermer syndrome
Zollinger-Ellison Syndrome
Sipple syndrome
MEN2B Syndrome
Michaelis-Gutmann bodies, are pathognomonic of which of the following mechanisms of disease?
Abnormal iron metabolism within renal tubular epithelial cells
Lipid-laden macrophages in response to chronic inflammation
Accumulation of undigested bacterial remnants due to defective phagolysosomal function in macrophages
Intracytoplasmic inclusion formation due to viral cytopathic effect
Diagnostic hallmark of Frontotemporal Lobar Degeneration is
Kuru plaques
Pick bodies
Lewy bodies
Neuritic plaques
Bulky friable cardiac vegetations are seen in which of the following disease?
Nonbacterial thrombotic endocarditis
Libman-Sacks endocarditis
Infective endocarditis
Rheumatic heart disease
High grade serous carcinoma of ovary is associated with which of the following mutation
FOXL2
PTEN
KRAS
TP53
The causative agent of bacterial enterocolitis in an immunocompromised elderly hospitalized patient is ?
Campylobacter jejuni
Flexner-Wintersteiner rosettes are most characteristically found in which of the following tumors?
Neuroblastoma
Nephroblastoma
Retinoblastoma
Medulloblastoma
