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SYNAPTIX SCREENING ROUND!

Total questions: 30

Worksheet time: 15mins

Name
Class
Date
1.

Which of the following antibiotics inhibits bacterial cell wall synthesis?

a)

Gentamicin

b)

Erythromycin

c)

Penicillin

d)

Ciprofloxacin

2.

A female with facial swelling, oliguria, and hematuria post throat infection. Likely diagnosis?

a)

IgA nephropathy

b)

Post-streptococcal glomerulonephritis

c)

Goodpasture syndrome

d)

Lupus nephritis

3.

Clinical-based: A baby is born with a midline swelling in the lower back, covered by skin. Neurological examination is normal. Most likely diagnosis?

a)

Meningocele

b)

Myelomeningocele

c)

Spina bifida occulta

d)

Dermoid cyst

4.

Which drug shows a zero-order kinetic profile at high doses?

a)

Aspirin

b)

Paracetamol

c)

Amoxicillin

d)

Atenolol

5.

In malaria, which species is most commonly associated with relapse?

a)

Plasmodium falciparum

b)

Plasmodium vivax

c)

Plasmodium malariae

d)

Plasmodium knowlesi

6.

A child presents with vomiting, lethargy, and a mousy odor. Most likely diagnosis?

a)

Maple syrup urine disease

b)

Phenylketonuria

c)

Tyrosinemia

d)

Alkaptonuria

7.

The structure passing through the foramen spinosum is:

a)

Mandibular nerve

b)

Middle meningeal artery

c)

Inferior alveolar nerve

d)

Facial artery

8.

A patient with difficulty in swallowing and loss of gag reflex on one side likely has a lesion of:

a)

CN VII

b)

CN IX

c)

CN XII

d)

None of the above

9.

A young man presents with wrist drop after a mid-shaft humerus fracture. Which nerve is most likely injured?

a)

Ulnar nerve

b)

Median nerve

c)

Radial nerve

d)

Axillary nerve

10.

Clinical-based: A hypertensive pregnant woman is started on alpha-methyldopa. It acts by:

a)

Blocking beta-1 receptors

b)

Stimulating alpha-2 receptors in CNS

c)

Blocking calcium channels

d)

Inhibiting angiotensin II

11.

Reed-Sternberg cells are characteristically seen in:

a)

Non-Hodgkin lymphoma

b)

Hodgkin lymphoma

c)

Burkitt lymphoma

d)

Chronic lymphocytic leukemia

12.

Clinical-based: A patient is found to have a heart rate of 48/min with absent P waves. The pacemaker site is most likely:

a)

SA node

b)

AV node

c)

Purkinje fibers

d)

Left bundle branch

13.

Which of the following factors increases glomerular filtration rate (GFR)?

a)

Constriction of afferent arteriole

b)

Constriction of efferent arteriole (moderate)

c)

Sympathetic stimulation

d)

Decrease in renal plasma flow

14.

A patient is prescribed atropine before surgery. The main purpose is to:

a)

Induce sedation

b)

Decrease salivation

c)

Prevent vomiting

d)

Induce muscle relaxation

15.

The Sabouraud dextrose agar is used for isolation of:

a)

Bacteria

b)

Fungi

c)

Parasites

d)

Viruses

16.

Assertion (A): Naloxone is used in opioid overdose. Reason (R): Naloxone activates opioid receptor in brain.

a)

Both A and R are true, and R is the correct explanation

b)

Both A and R are true, but R is not the correct explanation

c)

A is true, R is false

d)

A is false, R is true

17.

Assertion (A): Mycobacterium tuberculosis easily decolorises with acid alcohol. Reason (R): It has mycolic acid in its cell wall.

a)

Both A and R are true, and R is the correct explanation

b)

Both A and R are true, but R is not the correct explanation

c)

A is true, R is false

d)

A is false, R is true

18.

Which vitamin is involved in transamination reactions?

a)

Vitamin B1

b)

Vitamin B6

c)

Vitamin B12

d)

Vitamin C

19.

A 45-year-old alcoholic presents with jaundice, spider angiomas, and gynecomastia. Likely underlying pathology?

a)

Cirrhosis

b)

Hepatitis A

c)

Hemochromatosis

d)

Wilson’s disease

20.

In a 24-hour urine collection, creatinine clearance is used to estimate:

a)

Renal blood flow

b)

Glomerular filtration rate

c)

Tubular secretion

d)

Tubular reabsorption

21.

Assertion (A): Liquifactive necrosis is typically seen in myocardial infarction. Reason (R): Hypoxia leads to denaturation of structural proteins.

a)

Both A and R are true, and R is the correct explanation

b)

Both A and R are true, but R is not the correct explanation

c)

A is true, R is false

d)

A is false, R is true

22.

Clinical-based: A patient with hemolytic anemia is found to have decreased G6PD activity. The role of G6PD is in:

a)

Oxidative phosphorylation

b)

Urea cycle

c)

Pentose phosphate pathway

d)

Glycogenolysis

23.

Assertion (A): Glycogen is branched. Reason (R): Branching makes glycogen more compact and soluble.

a)

Both A and R are true, and R is the correct explanation

b)

Both A and R are true, but R is not the correct explanation

c)

A is true, R is false

d)

A is false, R is true

24.

Which enzyme deficiency leads to galactose accumulation and cataract in infants?

a)

Galactokinase

b)

Aldolase B

c)

GALT

d)

Glucokinase

25.

Clinical-based: A woman presents with frothy vaginal discharge, fishy odor, and clue cells on microscopy. Most likely diagnosis?

a)

Candidiasis

b)

Trichomoniasis

c)

Bacterial vaginosis

d)

Gonorrhea

26.

Assertion (A): CO₂ is more soluble in plasma than O₂. Reason (R): CO₂ forms bicarbonate in the blood.

a)

Both A and R are true, and R is the correct explanation

b)

Both A and R are true, but R is not the correct explanation

c)

A is true, R is false

d)

A is false, R is true

27.

Which of the following is a tumor marker for hepatocellular carcinoma?

a)

PSA

b)

CA-125

c)

CEA

d)

AFP

28.

Assertion (A): The medial longitudinal arch is maintained by the long plantar ligament. .Reason (R): The spring ligament supports the head of the talus.

a)

Both A and R are true, and R is the correct explanation

b)

Both A and R are true, but R is not the correct explanation

c)

A is true, R is false

d)

A is false, R is true

29.

Assertion (A): Glycogen is linear in structure. Reason (R): Linearity makes glycogen more compact and soluble.

a)

Both A and R are true, and R is the correct explanation

b)

Both A and R are true, but R is not the correct explanation

c)

A is true, R is false

d)

A is false, R is false

30.

A patient has low serum calcium but normal phosphate. PTH is elevated. What is the most likely cause?

a)

Vitamin D deficiency

b)

Primary hyperparathyroidism

c)

Chronic renal failure

d)

Hypoparathyroidism