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Anaesthesia RIMS Quiz

Total questions: 40

Worksheet time: 30mins

Name
Class
Date
1.

Which of the following best explains why pregnant women are more prone to gastroesophageal reflux?

a)

Increased gastric acid secretion during pregnancy

b)

Elevated progesterone levels relaxing the lower esophageal sphincter

c)

Displacement of the esophagus by the growing uterus

d)

Increased peristaltic movement of the intestines

2.

Despite an increase in plasma volume during pregnancy, hematocrit levels decrease. What is the primary mechanism behind this change?

a)

Suppression of erythropoietin by estrogen

b)

Selective destruction of red blood cells

c)

Disproportionate increase in plasma volume compared to red cell mass

d)

Hemodilution due to reduced renal erythropoietin clearance

3.

A 48‑year‑old with a massive multinodular goitre, stridor when supine, and limited neck extension presents for urgent tracheostomy. Which airway strategy offers the safest first‑attempt success while minimizing loss of airway tone?

a)

Awake flexible bronchoscopic intubation under topical anaesthesia with oxygenation maintained

b)

Inhalational induction maintaining spontaneous ventilation, then direct laryngoscopy

c)

Rapid‑sequence induction with video laryngoscopy and rocuronium

d)

Elective surgical tracheostomy under local without any airway instrumentation

4.

A pregnant woman in her third trimester develops mild dyspnea. Which physiological change most likely contributes to this symptom?

a)

Decreased tidal volume

b)

Increased functional residual capacity

c)

Increased progesterone-mediated central respiratory drive

d)

Decreased oxygen demand

5.

Cardiac output increases significantly in pregnancy. Which of the following is the most accurate explanation of this phenomenon?

a)

Increased systemic vascular resistance

b)

Increased heart rate and stroke volume

c)

Decreased venous return

d)

Increased cardiac contractility due to estrogen

6.

A hyperthyroid patient with Graves’ disease requires urgent open reduction and internal fixation. HR 140/min (irregularly irregular), BP 150/70, T 37.5 °C. What is the most appropriate immediate pre‑operative intervention?

a)

Start methimazole; delay surgery 48 h

b)

Give saturated solution of potassium iodide immediately

c)

Begin esmolol infusion to control rate, then proceed with optimization as time allows

d)

Administer high‑dose propylthiouracil (PTU) and proceed immediately

7.

During pregnancy, renal plasma flow and glomerular filtration rate (GFR) both increase. What clinical consequence might this have on routine lab interpretation?

a)

Elevated serum urea and creatinine levels

b)

Increased threshold for glucose reabsorption.

c)

Lower serum creatinine compared to non-pregnant levels

d)

Hyperkalemia due to aldosterone suppression

8.

A patient with TBI is being managed conservatively. What is the best indicator of adequate cerebral perfusion in the absence of invasive ICP monitoring?

a)

Urine output > 0.5 mL/kg/hr

b)

Glasgow Coma Scale improving

c)

Mean arterial pressure > 65 mmHg

d)

Maintenance of CPP surrogate (MAP >90 mmHg and clinical signs of cerebral function)

9.

Which of the following hormonal effects contributes to the development of physiological anemia in pregnancy?

a)

Increased erythropoietin production outpaced by plasma expansion

b)

Progesterone-mediated diuresis

c)

Estrogen-induced bone marrow suppression

d)

Decreased aldosterone levels reducing plasma volume

10.

During maintenance anaesthesia in an inadequately controlled thyrotoxic patient, BP falls to 85/45 with HR 125/min. Which vasoactive agent is most appropriate to treat hypotension while avoiding exacerbation of tachyarrhythmia?

a)

Ephedrine bolus

b)

Phenylephrine bolus or infusion

c)

Dobutamine infusion

d)

Isoproterenol infusion

11.

Why does pregnancy predispose to a hypercoagulable state?

a)

Increased platelet count due to hormonal stimulation

b)

Enhanced fibrinolytic activity

c)

Increased levels of antithrombin III

d)

Elevated levels of clotting factors like fibrinogen and Factor VIII

12.

The volume of oxygen remaining in a full E-cylinder is approximately 660 L. If the flow rate is 5 L/min, how long will the cylinder last if the pressure reads 1000 psi (starting from 2000 psi full)?

a)

66 minutes

b)

132 minutes

c)

100 minutes

d)

330 minutes

13.

A 62‑year‑old with severe hypothyroidism (myxoedema), bradycardia (HR 48), hypothermia, and low EF needs emergent laparotomy for peritonitis. Which induction plan best balances haemodynamic stability?

a)

High‑dose propofol with fentanyl

b)

Thiopentone induction with non‑depolariser paralysis

c)

Ketamine‑based induction with cautious opioid use and vigilant temperature management

d)

Midazolam–fentanyl only, avoiding any induction agent

14.

Which change in respiratory physiology during pregnancy helps in maintaining a favorable environment for fetal oxygenation?

a)

Decreased minute ventilation

b)

Development of respiratory acidosis

c)

Increased arterial CO₂ tension

d)

Mild compensated respiratory alkalosis

15.

Thirty minutes into a thyroidectomy, the patient develops T 39.5 °C, HR 150, and hypertension. Ventilation has been increased; end‑tidal CO₂ remains normal and there is no muscle rigidity. Which finding most supports thyroid storm over malignant hyperthermia?

a)

Rapidly rising ETCO₂ despite increased minute ventilation

b)

Masseter spasm after succinylcholine

c)

Mixed respiratory–metabolic acidosis with hyperkalaemia and myoglobinuria

d)

Warm, moist skin with tachyarrhythmia and absence of rigidity

16.

Which cardiovascular adaptation is responsible for systolic flow murmurs commonly heard in pregnancy?

a)

Aortic stenosis

b)

Increased blood viscosity

c)

Increased blood volume and flow across normal valves

d)

Pulmonary hypertension

17.

Which of the following is the most accurate explanation for the increased risk of urinary tract infections in pregnancy?

a)

Increased glomerular filtration rate

b)

Progesterone-induced relaxation of smooth muscle in ureters

c)

Compression of the bladder by the fetus

d)

Decreased urine output due to reduced renal perfusion

18.

For thyroidectomy with recurrent laryngeal nerve (RLN) monitoring, which neuromuscular blocker strategy is optimal?

a)

Use a short‑acting NMB for intubation only (or none), then avoid further NMBs and titrate anaesthesia/analgesia; confirm TOF recovery before monitoring

b)

Avoid neuromuscular blockers entirely; intubate with deep volatile alone

c)

Intubate with succinylcholine, then rocuronium infusion throughout

d)

Use cisatracurium infusion at low dose throughout to prevent movement

19.

A 55‑year‑old with long‑standing overt hypothyroidism presents for elective hernia repair. Which statement is most accurate for intra‑operative anaesthetic management compared with a euthyroid patient?

a)

MAC requirements are increased; higher volatile concentrations are needed

b)

Greater sensitivity to sedatives/opioids with risk of hypoventilation and delayed emergence

c)

Faster gastric emptying reduces aspiration risk under GA

d)

Non‑depolarising neuromuscular blocker duration is reliably shorter

20.

A 45-year-old male with severe TBI is admitted to ICU. His ICP is persistently elevated despite head elevation and sedation. MAP is 90 mmHg, ICP is 28 mmHg. What is the most appropriate next step to improve cerebral perfusion pressure (CPP)?

a)

Initiate hyperventilation to reduce PaCO₂ below 25 mmHg

b)

Start vasopressors to increase MAP to 110 mmHg

c)

Administer a bolus of hypertonic saline

d)

Begin therapeutic hypothermia at 32°C

21.

In the context of TBI, which of the following strategies best reflects an evidence-based approach to prevent secondary brain injury during initial ICU care?

a)

Routine use of corticosteroids to reduce cerebral edema

b)

Aggressive hyperventilation to PaCO₂ < 25 mmHg for all patients

c)

Keeping serum sodium < 135 mmol/L to reduce excitotoxicity

d)

Maintenance of normocapnia and normoxia with adequate sedation

22.

A patient with moderate TBI is found to have frequent episodes of hypertension and tachycardia unrelated to pain. What is the most likely cause, and how should it be managed initially?

a)

Increased ICP; start mannitol

b)

Sympathetic storm; initiate beta-blockade or clonidine

c)

Undiagnosed infection; start broad-spectrum antibiotics

d)

Neurogenic shock; administer IV fluids and vasopressors

23.

In a patient with severe TBI and no surgical lesion, which sedation strategy optimally balances ICP control and neurological assessment?

a)

Continuous high-dose midazolam infusion

b)

Propofol infusion titrated to ICP and sedation goals

c)

Long-acting benzodiazepines with muscle relaxants

d)

Intermittent boluses of opioids and paralytics

24.

A cylinder of nitrous oxide is transported in a poorly ventilated van during summer. The temperature inside reaches 60°C. What is the most likely hazard according to gas storage principles?

a)

Cylinder explosion due to Boyle’s Law

b)

Rapid decomposition of nitrous oxide due to Charles’ Law

c)

Activation of the fusible plug to release pressure

d)

Cracking of valve due to contraction of gas

25.

An oxygen E-cylinder is read as empty after prolonged use in the OR. Which principle best explains the inability to calculate the remaining content by pressure gauge alone in a nitrous oxide cylinder but not in an oxygen cylinder?

a)

Boyle’s Law applies only to oxygen, not nitrous oxide

b)

Nitrous oxide exists as a compressed gas throughout its use

c)

Pressure gauge in nitrous oxide remains constant until all liquid vaporizes

d)

Nitrous oxide follows Dalton’s Law and not Henry’s Law

26.

A patient on a ventilator using compressed gases shows a sudden drop in inspired oxygen concentration. Which system component failure would most likely bypass the safety features and lead to hypoxic delivery?

a)

Malfunction of the proportioning system (e.g., Link-25)

b)

Activation of fail-safe system due to nitrous oxide loss

c)

Failure of oxygen pressure sensor shut-off valve

d)

Disconnection at the common gas outlet

27.

During a pre-use check, an anaesthesia machine shows pipeline crossover, where nitrous oxide is being delivered through the oxygen pipeline. What is the most immediate action to ensure patient safety?

a)

Disconnect pipeline gas supply and switch to cylinder oxygen

b)

Administer 100% nitrous oxide briefly to avoid hypoxia

c)

Turn off the anaesthesia machine and cancel the case

d)

Use the oxygen flush valve to bypass the vaporizer

28.

A desflurane vaporizer is functioning suboptimally at high altitude. Which gas law best explains why the vaporizer might overdeliver agent under these conditions?

a)

Boyle’s Law

b)

Dalton’s Law

c)

Charles’ Law

d)

Henry’s Law

29.

A 3-year-old child requires a CT scan. He is anxious and uncooperative. Which sedation method provides optimal conditions while minimizing the risk of respiratory depression?

a)

Oral midazolam followed by chloral hydrate

b)

Intranasal dexmedetomidine

c)

IV propofol bolus with oxygen supplementation

d)

Inhalational sevoflurane with a face mask

30.

During sedation for fracture reduction in a 4-year-old, the child develops apnea after a bolus of propofol. What is the immediate management priority?

a)

Start IV fluids and call for help

b)

Administer naloxone to reverse the sedation

c)

Perform airway opening maneuvers and assist ventilation

d)

Give flumazenil to reverse benzodiazepine effects

31.

Which of the following reflects the most appropriate combination for procedural sedation in a child requiring painful dressing change in the emergency department?

a)

Oral midazolam and IV paracetamol

b)

Intramuscular ketamine alone

c)

IV dexmedetomidine and local lignocaine

d)

Inhaled nitrous oxide with intranasal fentanyl

32.

A 6-year-old child undergoing dental extraction under sedation becomes unresponsive to verbal commands but maintains airway reflexes. According to sedation levels, this is classified as:

a)

Minimal sedation

b)

Moderate sedation

c)

Deep sedation

d)

General anaesthesia

33.

A child with a history of obstructive sleep apnea requires MRI under sedation. Which agent is the safest choice with the least impact on respiratory drive?

a)

Propofol infusion

b)

Dexmedetomidine infusion

c)

Midazolam bolus

d)

Ketamine bolus

34.

While designing a study to evaluate the effect of a new sedative agent in children, which of the following best reflects the importance of defining a primary outcome clearly?

a)

To simplify data collection

b)

To allow flexibility in statistical analysis

c)

To avoid data loss during the trial

d)

To ensure the study is adequately powered and hypothesis-driven

35.

A postgraduate student is planning a randomized controlled trial on intraoperative fluid strategies. Which principle ensures that neither the patient nor the assessor knows the intervention being given?

a)

Stratified randomization

b)

Allocation concealment

c)

Blinding

d)

Intention-to-treat analysis

36.

A student designing a cross-sectional study on burnout among anaesthesiologists must consider which of the following as the most significant limitation of the design?

a)

Difficulty in obtaining ethical clearance

b)

Inability to capture prevalence rates

c)

Inability to establish causal relationships

d)

Need for large sample sizes

37.

A 60-year-old obese patient with limited neck extension is posted for elective hernia repair. The anaesthesia team plans to use video laryngoscopy for intubation. What is the primary advantage of this approach in such patients?

a)

It provides a magnified and indirect view of the glottis

b)

It avoids the need for muscle relaxants

c)

It completely eliminates the risk of airway trauma

d)

It allows faster intubation than all other methods

38.

In which of the following situations is the use of video laryngoscopy most likely to improve first-pass intubation success compared to direct laryngoscopy?

a)

Routine intubation in ASA I patient with full neck mobility

b)

Pediatric patients requiring uncuffed tubes

c)

Patients requiring nasotracheal intubation under sedation

d)

Anticipated difficult airway due to cervical spine immobilization

39.

A 70-year-old ICU patient on high-dose vasopressors requires percutaneous tracheostomy. Which factor most strongly supports bedside tracheostomy over OR transfer?

a)

ICU has less risk of infection than the OR

b)

The patient’s hemodynamic instability makes transport unsafe

c)

Percutaneous tracheostomy cannot be performed in the OR

d)

ICU staff are more skilled at tracheostomy than surgical teams

40.

In a septic ICU patient with rapidly worsening abdominal distension and suspected abdominal compartment syndrome, which of the following best justifies performing decompressive laparotomy at the bedside?

a)

Immediate access can prevent irreversible organ dysfunction

b)

Better sterility in the ICU environment

c)

Reduced surgical workload in the OR

d)

Avoidance of general anesthesia in unstable patients