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WorksheetsImmunoinformatics 1st Class Quiz
Total questions: 20
Worksheet time: 15mins
Which molecular structure helps the immune system differentiate between self and non-self antigens?
PAMPs
TLRs
MHC
Cytokines
Which of the following cells is a part of innate immunity and directly kills virus-infected cells?
B cell
NK cell
Helper T cell
Cytotoxic T cell
What is a key difference between innate and adaptive immunity?
Adaptive immunity responds first
Innate immunity requires memory cells
Adaptive immunity is antigen-specific
Innate immunity uses antibodies
Where do B cells undergo maturation?
Thymus
Bone marrow
Spleen
Lymph nodes
What is the primary source of hematopoiesis in adults?
Liver
Thymus
Bone marrow
Spleen
Which cell type bridges innate and adaptive immunity by antigen presentation?
Eosinophil
Dendritic cell
NK cell
Plasma cell
Plasma cells are derived from:
T cells
NK cells
B cells
Macrophages
MHC Class I molecules present antigen to:
B cells
Helper T cells
Cytotoxic T cells
NK cells
Why are red blood cells excluded from MHC-I presentation?
They are too small
They lack a nucleus
They cannot produce proteins
They lack CD4 receptors
Which type of MHC is only found on professional APCs?
MHC-I
MHC-II
HLA-A
HLA-C
Which molecule ensures complete T cell activation?
TCR
CD4
CD80/86
Fc receptor
Which APC does not use phagocytosis to internalize antigens?
Macrophage
Dendritic cell
B cell
Neutrophil
TLRs are mainly involved in recognizing:
Cytokines
Antibodies
PAMPs
Chemokines
Which region of the antibody binds to antigen?
Fc region
Constant region
Light chain
Variable region
Which of the following best describes the role of the thymus in immune education?
Antibody production
Self-reactive T cell elimination
NK cell activation
RBC synthesis
During hematopoiesis, the differentiation of lymphoid progenitors results in:
Neutrophils and monocytes
Erythrocytes and eosinophils
B cells, T cells, NK cells
Platelets and dendritic cells
The variability of MHC molecules among individuals primarily affects:
Cytokine signaling
Vaccine storage
Organ transplant compatibility
RBC survival
Which class of MHC presents endogenous (intracellular) antigens?
MHC-I
MHC-II
MHC-III
CD4
Autoimmune diseases are most often associated with defects in:
Antibody diversity
MHC-II upregulation
Self-tolerance mechanisms
Plasma cell activity
T cells mature in:
Spleen
Thymus
Appendix
Peyer’s patches
