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Learning Objectives

Total questions: 99

Worksheet time: 50mins

Name
Class
Date
1.

Define pharmaceutics and pharmacokinetics and explain their importance in pharmacy.

a)

Pharmaceutics is the science of dosage form design, while pharmacokinetics is the study of how drugs move through the body. Both are important in pharmacy for ensuring effective and safe medication use.

b)

Pharmaceutics is the study of drug interactions, while pharmacokinetics is the science of plant-based medicines. Both are important for herbal medicine preparation.

c)

Pharmaceutics is the process of drug approval, while pharmacokinetics is the study of drug marketing. Both are important for pharmaceutical business management.

d)

Pharmaceutics is the science of drug pricing, while pharmacokinetics is the study of drug patents. Both are important for pharmacy economics.

2.

Identify and describe examples of drug and pharmaceutical excipients.

a)

Examples of drug excipients include binders, fillers, disintegrants, lubricants, and preservatives.

b)

Examples of drug excipients include antibiotics, analgesics, and antihistamines.

c)

Examples of drug excipients include vaccines, hormones, and enzymes.

d)

Examples of drug excipients include vitamins, minerals, and amino acids.

3.

Compare and contrast drug, dosage forms, and drug delivery systems.

a)

A drug is the active pharmaceutical ingredient, dosage forms are the physical forms in which drugs are produced (e.g., tablets, capsules), and drug delivery systems are methods or devices for delivering drugs to the body.

b)

A drug is the device used to administer medication, dosage forms are only liquids, and drug delivery systems are the chemical structure of the drug.

c)

A drug is the packaging material, dosage forms are the flavors added to medicines, and drug delivery systems are the inactive ingredients.

d)

A drug is the method of administration, dosage forms are the routes of absorption, and drug delivery systems are the shapes of tablets.

4.

Differentiate chemical, brand, and generic (INN and USAN) drug names.

a)

Chemical names describe the chemical structure, brand names are given by manufacturers, and generic names (INN and USAN) are standardized nonproprietary names.

b)

Chemical names are always the same as brand names, while generic names are unique to each country.

c)

Brand names are standardized internationally, while chemical and generic names are chosen by manufacturers.

d)

Generic names (INN and USAN) are proprietary, while chemical and brand names are nonproprietary.

5.

Describe factors to consider in dosage form design.

a)

Factors include drug properties, route of administration, patient compliance, stability, and release profile.

b)

Only the color and taste of the drug are important.

c)

Dosage form design depends solely on marketing strategies.

d)

The only factor is the cost of production.

6.

Retrieve drug information from reliable online sources.

a)

Reliable online sources include PubMed, FDA website, and drug information databases like Lexicomp and Micromedex.

b)

Social media platforms like Facebook and Twitter are the best sources for drug information.

c)

Personal blogs and forums provide the most accurate drug information.

d)

Wikipedia is the only reliable source for drug information.

7.

List and describe common dosage forms and identify the nature of the API within them.

a)

Common dosage forms include tablets, capsules, solutions, and suspensions. The API is the active ingredient responsible for the drug's effect.

b)

Common dosage forms include only liquids and creams. The API is always an inactive ingredient.

c)

Common dosage forms are limited to injectables and ointments. The API is the preservative in the formulation.

d)

Common dosage forms include only powders and gels. The API is the coloring agent in the drug.

8.

Compare and contrast enteral and parenteral routes of administration.

a)

Enteral routes involve the gastrointestinal tract (oral, rectal), while parenteral routes bypass it (injection, infusion).

b)

Enteral routes are only used for emergency medications, while parenteral routes are used for long-term therapy.

c)

Parenteral routes involve the gastrointestinal tract, while enteral routes bypass it.

d)

Both enteral and parenteral routes exclusively use oral administration.

9.

Describe the features of common routes of administration.

a)

Common routes include oral, intravenous, intramuscular, and subcutaneous, each with specific absorption rates and uses.

b)

All routes of administration have identical absorption rates and are used interchangeably.

c)

Only oral administration is considered a common route for all medications.

d)

Common routes include only topical and inhalational methods, excluding injections.

10.

Define bioavailability and describe factors that influence bioavailability.

a)

Bioavailability is the proportion of a drug that enters circulation and is available for action. Factors include drug formulation, route of administration, and metabolism.

b)

Bioavailability is the rate at which a drug is excreted from the body. Factors include kidney function, age, and hydration.

c)

Bioavailability is the ability of a drug to bind to plasma proteins. Factors include protein levels, drug solubility, and temperature.

d)

Bioavailability is the process by which a drug is metabolized in the liver. Factors include liver enzyme activity, diet, and genetic makeup.

11.

Describe ADME processes.

a)

ADME stands for Absorption, Distribution, Metabolism, and Excretion, which are the processes drugs undergo in the body.

b)

ADME stands for Antibody, Digestion, Mutation, and Elimination, which are the processes drugs undergo in the body.

c)

ADME stands for Absorption, Digestion, Metabolism, and Excretion, which are the processes nutrients undergo in the body.

d)

ADME stands for Assimilation, Distribution, Mutation, and Excretion, which are the processes drugs undergo in the body.

12.

Compare and contrast the processes a drug goes through following oral and IV administration.

a)

Oral administration involves absorption through the GI tract and first-pass metabolism, while IV administration delivers the drug directly into the bloodstream, bypassing absorption and first-pass effect.

b)

Oral administration delivers the drug directly into the bloodstream, while IV administration requires absorption through the GI tract and first-pass metabolism.

c)

Both oral and IV administration involve absorption through the GI tract and first-pass metabolism.

d)

IV administration is always slower than oral administration due to the need for absorption.

13.

Define first pass metabolism.

a)

First pass metabolism is the initial metabolism of a drug in the liver after oral administration, before it reaches systemic circulation.

b)

First pass metabolism is the process by which drugs are excreted unchanged in the urine.

c)

First pass metabolism refers to the breakdown of drugs in the stomach before absorption.

d)

First pass metabolism is the conversion of drugs into active metabolites in the kidneys.

14.

Explain the relationship between pharmaceutics and pharmacokinetics.

a)

Pharmaceutics affects how a drug is formulated and delivered, which in turn influences its pharmacokinetics (absorption, distribution, metabolism, excretion).

b)

Pharmaceutics and pharmacokinetics are unrelated fields with no impact on each other.

c)

Pharmacokinetics determines the chemical structure of drugs, while pharmaceutics studies their side effects.

d)

Pharmaceutics only deals with drug marketing, while pharmacokinetics focuses on patient compliance.

15.

What is pharmaceutics?

a)

Pharmaceutics is the science of dosage form design, manufacturing, and delivery to the site of action.

b)

Pharmaceutics is the study of plant-based medicines only.

c)

Pharmaceutics is the process of diagnosing diseases.

d)

Pharmaceutics is the art of preparing herbal teas.

16.

Which of the following is NOT listed as an importance of pharmaceutics to pharmacy?

a)

Formulation

b)

Stability

c)

Effectiveness

d)

Diagnosis

e)

Manufacturing

17.

List one importance of pharmaceutics to pharmacy.

a)

Formulation, Stability, Effectiveness, or Manufacturing

b)

Coloring agents in tablets

c)

Packaging design only

d)

Advertising pharmacy products

18.

Which exam includes questions on pharmaceutics as part of its foundational knowledge for pharmacy practice?

a)

NAPLEX

b)

USMLE

c)

MCAT

d)

DAT

19.

How many questions in Domain 1 of the NAPLEX exam are related to calculations, pharmaceutics, pharmacokinetics, and pharmacodynamics?

a)

50 questions (25% of exam)

b)

30 questions (15% of exam)

c)

70 questions (35% of exam)

d)

100 questions (50% of exam)

20.

Understanding the reasoning behind dosing schedules and available dosage forms makes memorizing easier.

a)

True

b)

False

21.

Name two topics included in Domain 1 of the NAPLEX exam.

a)

calculations, pharmaceutics, pharmacokinetics, pharmacodynamics

b)

anatomy, physiology, biochemistry, genetics

c)

microbiology, immunology, pathology, surgery

d)

psychiatry, neurology, cardiology, dermatology

22.

According to the FDA definition provided, what is a drug?

a)

Any product approved for the use in diagnosis, cure, mitigation, treatment, or prevention of disease; and that is intended to affect structure or any function of the body.

b)

Any substance used only for cosmetic purposes and not intended to affect the structure or function of the body.

c)

Any food product that provides nutritional value but does not affect the structure or function of the body.

d)

Any device used externally on the body for physical support or protection.

23.

Based on the FDA definition, a drug is:

a)

A substance intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease.

b)

A type of food supplement for daily nutrition.

c)

A device used for physical therapy.

d)

A vitamin that boosts energy levels.

24.

What is the physical form of a pharmaceutical formulation called?

a)

Dosage form

b)

Solution

c)

Suspension

d)

Excipient

25.

Pharmaceutical excipients are also known as ______ ingredients.

a)

inactive

b)

active

c)

volatile

d)

reactive

26.

Which of the following is NOT a common pharmaceutical dosage form?

a)

Tablets

b)

Suppositories

c)

Gels

d)

Fruits

27.

Is the following statement True or False? 'Capsules are a common pharmaceutical dosage form.'

a)

True

b)

False

28.

Select the option that lists three common pharmaceutical dosage forms.

a)

Tablets, capsules, and syrups

b)

Tablets, injections, and bandages

c)

Capsules, ointments, and thermometers

d)

Syrups, plasters, and stethoscopes

29.

Fill in the blank: A vehicle for convenient and safe delivery of accurate and precise dose of an active pharmaceutical ingredient combined with pharmaceutical excipients is called a ______.

a)

dosage form

b)

suspension

c)

capsule

d)

syrup

30.

Which of the following is a pharmaceutical excipient?

a)

Active ingredient

b)

Inactive ingredient

c)

Water only

d)

None of the above

31.

What are drug delivery systems?

a)

Specialized dosage forms with a specific drug release rate and/or a pre-programmed drug released site

b)

Methods to increase drug prices

c)

Techniques to manufacture drugs faster

d)

Ways to store drugs for longer periods

32.

Which of the following is an example of a drug delivery system shown in the image?

a)

Nicotine Transdermal Patch

b)

BESPOSA (inotuzumab ozogamicin) for injection

c)

Calicheamicin-antibody conjugate

d)

All of the above

33.

Fill in the blank: Drug delivery systems are specialized dosage forms with a specific _______ and/or a pre-programmed drug released site.

a)

drug release rate

b)

color

c)

taste

d)

shape

34.

What is the brand name of the medication shown on the product label?

a)

Lipitor

b)

Zocor

c)

Crestor

d)

Pravachol

35.

What is the dosage strength of each Lipitor tablet as shown on the label?

a)

10 mg

b)

20 mg

c)

40 mg

d)

80 mg

36.

Lipitor contains which active ingredient?

a)

Simvastatin

b)

Atorvastatin calcium

c)

Rosuvastatin

d)

Pravastatin

37.

What is the dosage form of Lipitor as indicated on the label?

a)

Tablets

b)

Capsules

c)

Oral Solution

d)

Injection

38.

According to the label, at what temperature should Lipitor be stored?

a)

0-10°C (32-50°F)

b)

10-20°C (50-68°F)

c)

20-25°C (68-77°F)

d)

25-30°C (77-86°F)

39.

Where is Lipitor made, according to the product label?

a)

Ireland

b)

Germany

c)

United States

d)

India

40.

Who distributes Lipitor as shown on the label?

a)

Merck

b)

Parke-Davis, Division of Pfizer Inc

c)

AstraZeneca

d)

Novartis

41.

Based on the product label, what is the dosage form of Linezolid for Oral Suspension?

a)

Tablet

b)

Capsule

c)

Oral Suspension

d)

Suppository

42.

According to the product label, what is the strength of Diltiazem Hydrochloride Extended-Release Capsules, USP?

a)

100 mg

b)

240 mg

c)

0.4 mg

d)

25 mg

43.

Fill in the blank: The dosage form of Nitroglycerin Sublingual Tablets, USP is _________.

a)

Sublingual Tablet

b)

Oral Solution

c)

Topical Cream

d)

Injectable Suspension

44.

According to the product label, what is the strength of Prochlorperazine Suppositories?

a)

0.4 mg

b)

25 mg

c)

100 mg

d)

240 mg

45.

Which of the following is NOT a classification of dosage forms according to the image?

a)

A) Physical State

b)

B) Intended Action

c)

C) Duration of Action

d)

D) Chemical Structure

46.

Which of the following is NOT listed as a physical state of dosage forms?

a)

Dispersement Systems

b)

Solids

c)

Semi-solids

d)

Gases

47.

Fill in the blank: The two types of intended action for dosage forms are _______ and _______.

a)

Systemic, Local

b)

Oral, Topical

c)

Immediate, Delayed

d)

Solid, Liquid

48.

Which of the following is a route of administration according to the image?

a)

Oral

b)

Enteral

c)

Topical

d)

Inhalation

49.

Fill in the blank: The two types of duration of action for dosage forms are _______ and _______.

a)

Fast-acting, Long-acting

b)

Short-acting, Delayed-release

c)

Immediate-release, Extended-release

d)

Rapid-onset, Sustained-release

50.

Which of the following is NOT a route of administration listed in the image?

a)

A) Enteral

b)

B) Parenteral

c)

C) Topical

d)

D) None of the above

51.

Fill in the blank: The four main classifications of dosage forms are Physical State, Intended Action, Duration of Action, and _______.

a)

Route of Administration

b)

Chemical Structure

c)

Dosage Strength

d)

Packaging Type

52.

Which of the following is a physical state of dosage forms?

a)

Systemic

b)

Parenteral

c)

Liquids

d)

Long-acting

53.

Fill in the blank: One of the factors to consider in dosage form design is the therapeutic consideration of _______ state and patient.

a)

disease

b)

economic

c)

environmental

d)

nutritional

54.

Which of the following is a factor to consider in dosage form design?

a)

A) Physical and chemical properties of the API

b)

B) Marketing strategies

c)

C) Packaging design

d)

D) None of the above

55.

Fill in the blank: Biopharmaceutical _______ is a factor to consider in dosage form design.

a)

considerations

b)

reactions

c)

colors

d)

flavors

56.

Which of the following is a nature of illness to consider in dosage form design?

a)

Acute

b)

Chronic

c)

Both A and B

d)

None of the above

57.

What are the two manners in which an illness can be treated according to therapeutic considerations in dosage form design?

a)

Systemic and Local

b)

Acute and Chronic

c)

Direct and Indirect

d)

Primary and Secondary

58.

Which of the following is NOT a patient age group considered in dosage form design?

a)

A) Pediatric

b)

B) Geriatric

c)

C) Adult

d)

D) Both A and B

59.

Patient condition in dosage form design includes which of the following?

a)

Comatose

b)

Ambulatory

c)

Both A and B

d)

None of the above

60.

Name any two patient factors that can alter response to drugs.

a)

Patient age, Body weight

b)

Drug expiry date, Storage temperature

c)

Prescription handwriting, Pharmacy location

d)

Tablet color, Manufacturer logo

61.

Pregnancy is a patient factor that can alter response to drugs.

a)

True

b)

False

62.

Which of the following is a physiological factor that can alter drug response?

a)

Genetic make-up

b)

Milieu

c)

Physiological reserve

d)

All of the above

63.

Fill in the blank: ________ and ________ are two types of patient age groups considered in dosage form design.

a)

Pediatric and Geriatric

b)

Adult and Neonatal

c)

Adolescent and Infant

d)

Middle-aged and Elderly

64.

What is the disease to be treated according to the target drug product profile?

a)

Osteoarthritis

b)

Diabetes

c)

Hypertension

d)

Asthma

65.

What is the patient type for the target drug product profile?

a)

Adults over 40 years, including geriatric

b)

Children under 12 years

c)

Pregnant women only

d)

Athletes under 30 years

e)

Infants and toddlers

66.

What is the route of administration for the target drug product profile?

a)

Oral

b)

Intravenous

c)

Topical

d)

Inhalation

67.

What is the dosage/presentation for the target drug product profile?

a)

Immediate release tablet

b)

Extended release capsule

c)

Oral suspension

d)

Transdermal patch

68.

What is the dose and frequency for the target drug product profile?

a)

Once daily

b)

Twice weekly

c)

Every 8 hours

d)

Once monthly

69.

What are the aesthetic aspects for the target drug product profile?

a)

Color to differentiate strength, taste to reduce bitterness

b)

Shape to increase solubility, odor to enhance absorption

c)

Viscosity to improve stability, pH to increase shelf life

d)

Particle size to reduce cost, density to increase potency

70.

What dosage form is shown in the image?

a)

Tablet

b)

Capsule

c)

Syrup

d)

Injection

71.

What dosage form is shown in the image?

a)

Capsule

b)

Tablet

c)

Syrup

d)

Ointment

72.

What dosage form is shown in the image?

a)

Lozenge

b)

Tablet

c)

Capsule

d)

Syrup

73.

Look at the image of a spoon with liquid being poured. What dosage form is shown in the image?

a)

Syrup

b)

Tablet

c)

Capsule

d)

Ointment

74.

Look at the image of a spoon with powder. What dosage form is shown in the image?

a)

Powder

b)

Tablet

c)

Capsule

d)

Syrup

75.

Look at the image of a glass with blue liquid and a spoon. What dosage form is shown in the image?

a)

Oral solution

b)

Tablet

c)

Capsule

d)

Ointment

76.

Look at the image of a tube applying cream to skin. What dosage form is shown in the image?

a)

Topical cream/ointment

b)

Oral tablet

c)

Injectable solution

d)

Nasal spray

77.

What dosage form is shown in the image?

a)

Transdermal patch

b)

Oral tablet

c)

Nasal spray

d)

Eye drops

78.

What dosage form is shown in the image?

a)

Foam

b)

Tablet

c)

Ointment

d)

Solution

79.

What dosage form is shown in the image?

a)

Medicated shampoo

b)

Oral tablet

c)

Eye drops

d)

Topical ointment

80.

What dosage form is shown in the image?

a)

Eye drops

b)

Tablets

c)

Ointment

d)

Syrup

81.

What dosage form is shown in the image?

a)

Nasal spray

b)

Oral tablet

c)

Topical cream

d)

Eye drops

82.

What dosage form is shown in the image?

a)

Dry powder inhaler

b)

Oral tablet

c)

Transdermal patch

d)

Nasal spray

83.

Look at the image of a blue inhaler. What dosage form is shown in the image?

a)

Metered dose inhaler

b)

Nasal spray

c)

Oral tablet

d)

Topical cream

84.

What dosage form is shown in the image?

a)

Nebulizer solution

b)

Tablet

c)

Ointment

d)

Syrup

85.

Look at the image of a person receiving an intravenous injection. What dosage form is shown in the image?

a)

Intravenous injection

b)

Oral tablet

c)

Topical cream

d)

Inhalation spray

86.

Look at the image of a person receiving an intramuscular injection. What dosage form is shown in the image?

a)

Intramuscular injection

b)

Oral tablet

c)

Topical cream

d)

Inhalation aerosol

87.

Name one characteristic that pharmaceutical excipients help to formulate in an acceptable physical form.

a)

Size

b)

Color

c)

Taste

d)

Odor

88.

Name one characteristic that pharmaceutical excipients help to formulate in an acceptable physical form.

a)

Shape

b)

Color

c)

Taste

d)

Odor

89.

Name one characteristic that pharmaceutical excipients help to formulate in an acceptable physical form.

a)

Texture

b)

Color

c)

Odor

d)

Taste

90.

Name one characteristic that pharmaceutical excipients help to formulate in an acceptable physical form.

a)

Taste/odor

b)

Color of packaging

c)

Expiration date

d)

Manufacturer's address

91.

Name one characteristic that pharmaceutical excipients help to formulate in an acceptable physical form.

a)

Appearance

b)

Taste

c)

Color

d)

Odor

92.

Fill in the blank: One of the key attributes of pharmaceutical excipients is _________.

a)

Safety

b)

Color

c)

Flavor

d)

Sweetness

93.

Fill in the blank: One of the key attributes of pharmaceutical excipients is _________.

a)

Stability

b)

Color

c)

Sweetness

d)

Odor

94.

Fill in the blank: One of the key attributes of pharmaceutical excipients is _________.

a)

Solubility

b)

Toxicity

c)

Radioactivity

d)

Flammability

95.

Fill in the blank: One of the requirements of pharmaceutical excipients is that they should be ________ inert.

a)

physically

b)

chemically

c)

biologically

d)

thermally

96.

Fill in the blank: Pharmaceutical excipients must be ________-toxic.

a)

non

b)

high

c)

mild

d)

semi

97.

Fill in the blank: Pharmaceutical excipients should be physically and ________ stable.

a)

chemically

b)

biologically

c)

mechanically

d)

optically

98.

Fill in the blank: Pharmaceutical excipients should have no adverse effect on drug ________ or dosage form.

a)

stability

b)

color

c)

taste

d)

price

99.

Fill in the blank: Pharmaceutical excipients should be ________.

a)

inexpensive

b)

toxic

c)

unstable

d)

irritating

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