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Worksheets

BLOK 9 2018

Total questions: 113

Worksheet time: 59mins

Name
Class
Date
1.

What is the condition of blood pressure 140/90?

a)

Hypertension grade 1

b)

Hypertension grade 2

c)

Hypertension grade 3

d)

Systolic isolation

e)

Diastolic isolation

2.

Molecular carcinogenesis is influenced by various molecular components. Which of the following molecular components works analogously to a brake?

a)

Oncogene

b)

Proto-oncogene

c)

Mutated tumor suppressor gene

d)

Normal tumor suppressor gene

e)

Down regulation of proto-oncogene

3.

The complementary DNA of 5'-TACGATCATAT-3' is

a)

3'-ATGCTAGTATA-5'

b)

...

c)

...

d)

...

e)

...

4.

What plays an important role in distributing blood throughout the body?

a)

Aorta

b)

Arteries

c)

Arterioles

d)

Capillaries

e)

Veins

5.

Which drug is a substrate for the enzyme CYP2C19?

a)

Imipramine

b)

Desimipramine

c)

Haloperidol

d)

Omeprazole

e)

Amitriptyline

6.

To determine the maturation of B cell differentiation, what indicator is examined?

a)

Ig G

b)

Ig A

c)

Ig D

d)

Ig E

e)

Ig M

7.

A case of a woman with fever for 6 weeks, joint pain, and pale conjunctiva, splenomegaly.

a)

Examination with ANA and GCP(?)

b)

Examination for respiratory infection

c)

Urinary tract infection

d)

Infection present

e)

Anamnesis balalla

8.

There is a polymorphism in the beta 1 adrenergic. But the polymorphism is only on 1 allele DNA. What is the result in electrophoresis?

a)

1 band visible

b)

2 bands visible

c)

3 bands visible (previous answer)

d)

4 bands visible

e)

No bands visible

9.

In the case of Mr. Harun, it is known that at base 636 there is a substitution polymorphism of alanine (A) to guanine (G) with the DNA sequence GACTTGTTTTCAATTGCGCTTAATT. To determine the presence of polymorphism using the RFLP method, which restriction enzyme can recognize the polymorphism?

a)

A1uI (5'-AGCT-3')

b)

EcoRI (5'-GTTTTC-3')

c)

bamHI (5'-CATTCA-3')

d)

smaI (5'-TTAATT-3')

e)

haeIII (5'-CAATTG-3)

10.

What stressor causes death?

a)

Hypovolemic

b)

Hypoxia

c)

Hypotensive

d)

Hypo-systemic

e)

Hypogastric

11.

Mr. Harun, 50 years old, experienced an acute myocardial infarction despite having received clopidogrel to prevent thrombus formation. Upon examination, the serum level of clopidogrel was found to be lower. To determine the presence of polymorphism, what examination should be performed?

a)

PCR and RFLP

b)

PCR and ELISA

c)

PCR and IHK

d)

PCR and Spectrophotometry

e)

PCR and HPLC

12.

The sensory system that functions to generate energy from the environment and within the body is

a)

Limbic system

b)

Afferent

c)

Efferent

d)

...

e)

...

13.

Gestational age is 37 weeks with a weight of 1700. The baby is diagnosed as

a)

Baby full term according to gestation

b)

Baby full term small for gestation

c)

Baby preterm according to gestation

d)

Baby preterm small for gestation

e)

...

14.

A baby diagnosed with a gestational age of 39 weeks and a weight of 2100 grams.

a)

Baby is full term according to gestational age

b)

Baby is full term but small for gestational age

c)

Baby is preterm according to gestational age

d)

Baby is preterm and small for gestational age

e)

Baby is post-term according to gestational age

15.

A patient with hypertension receiving metoprolol shows no significant decrease in blood pressure despite following the medication regimen. What amino acid variant is present in the patient at codon 389 that contributes to this phenomenon?

a)

Glycine

b)

Alanine

c)

Tryptophan

d)

Arginine

e)

Serine

16.

A patient is unable to maintain electrolyte transport in and out of cells, has thick mucus secretion, lung infections, and obstruction, and has salty skin. The delta F508 mutation in the CFTR gene occurs during which process?

a)

Post translation: protein folding

b)

Transcription: polyadenylation signal

c)

Post transcription: glycosylation

d)

Post translation: protein targeting

e)

Translation: polypeptide chain

17.

A 17-year-old woman presents to the clinic with a complaint of three swollen lymph nodes in the neck that appeared three months ago. What is the name of the area?

a)

Submental

b)

Preauricular

c)

Supraclavicular

d)

Sternocleidomastoid

e)

Infraclavicular

18.

Which organ system regulates body fluids?

a)

Neuronal

b)

Urinary

c)

Integumentary

d)

Hormonal

e)

Cardiovascular

19.

What is the inspection point for the ictus cordis?

a)

ICS 5 medial to the left midclavicular line

b)

ICS 5 lateral to the left midclavicular line

c)

ICS 4 medial to the left midclavicular line

d)

ICS 4 lateral to the left midclavicular line

20.

Mr. Name, aged 50, has had his arm amputated. His weight is 50 kg. The distance between the tips of his middle fingers is 124 cm. The distance between the middle and ring fingers on both sides is 120 cm. What was Mr. Name's weight before the amputation?

a)

77

b)

79

c)

81

d)

83

e)

82

21.

Mr. Name, aged 50, has had his arm amputated. His weight is 50 kg. The distance between the tips of his middle fingers is 124 cm. The distance between the middle and ring fingers on both sides is 120 cm. What was Mr. Name's height before the amputation?

a)

142

b)

143

c)

144

d)

146

e)

148

22.

A 45-year-old man has a fever. Other complaints include chills and sweating, as well as nausea and vomiting. Today he has a cough and runny nose. What is the multisystem problem?

a)

Nausea

b)

Vomiting

c)

Chills

d)

Runny nose

e)

Fever

23.

In physiological conditions, which organ is consistently filled with blood (receives a consistent blood supply)?

a)

Neuronal

b)

Respiratory

c)

Digestive

d)

Urinary

e)

Cardiovascular

24.

In physiological conditions, which organ is consistently filled with blood?

a)

neuronal

b)

respiratory

c)

digestive

d)

urinary

e)

cardiovascular

25.

What causes visceral organ pain?

a)

Hypoxia

b)

mechanical trauma

c)

temperature

d)

...

e)

...

26.

What organ system is disturbed if the sclera is icteric (yellow)?

a)

Sensory

b)

Digestive

c)

Nervous

d)

Integumentary

e)

Cardiovascular

27.

Which gene therapy technique can be used in vivo?

a)

Gold bullet

b)

Liposomes

c)

Using viruses as carriers

d)

Using human artificial chromosomes

e)

Transposons

28.

Which risk factor is the highest for carcinogenesis?

a)

Infection

b)

Alcohol

c)

Tobacco

d)

Obesity

e)

Physical inactivity

29.

Examination using a sharp edge...

a)

Babinski

b)

Oppenheim

c)

...

d)

...

e)

no answer

30.

There is a question about weight... Height 165cm weight 80kg. What is the BMI category?

a)

Normal

b)

Overweight

c)

Underweight

d)

Obesity

e)

...

31.

Fever rises continuously without fluctuating more than 1°C.

a)

remittent

b)

continuous

c)

heptic

d)

septic

e)

intermittent

32.

Organ abnormalities in the lower left quadrant...

a)

Left lobe of the liver

b)

Stomach

c)

Ascending colon

d)

Descending colon

e)

Transverse colon

33.

Miss A, age so and so, has complaints of palpitations, wet hands... physical examination shows enlarged eyes, upper eyelid does not close so the sclera is fully visible...

a)

Stellwag's sign

b)

sign

c)

von Graefe's sign

d)

de Musset's sign

e)

...

34.

Various organs become organ systems based on?

a)

Shape

b)

Cell color

c)

Cell quantity

d)

Functional purpose

e)

Tissue attachment

35.

Rhonchi sound...

a)

... prolonged expiration

b)

...

c)

like a half-closed mouth

d)

...

e)

...

36.

A baby girl is born at 37 weeks gestation from a primigravida mother. The mother has had hypertension since 26 weeks of gestation. There is no history of ruptured membranes. The baby is born via C-section with an indication of PEB, and does not cry immediately. Upon physical examination, the birth weight is 1700 grams, length 49 cm, and head circumference 34 cm. What is the diagnosis based on the baby's birth weight?

a)

Normal birth weight

b)

Low birth weight

c)

Very low birth weight

d)

Extremely low birth weight

e)

Large baby

37.

A man suffers from a cough with phlegm for 2 months. Then he complains of coughing up blood for the last 5 days accompanied by fever. One year ago he had...

4 lines
38.

A man has been suffering from a cough with phlegm for the past 2 months. He then complains of coughing up blood for the past 5 days accompanied by fever. One year ago, he took TB medication for 1 month but did not continue because the symptoms had disappeared. Based on the scenario, what is the main complaint of the man?

a)

Suffering from TB for 1 year after stopping OAT

b)

Coughing up blood for the past 5 days accompanied by fever

c)

Coughing with phlegm for the past 2 months

d)

...

e)

...

39.

A baby boy was born with a weight of 2800 grams, a respiratory rate of 70 breaths per minute, mild intercostal retraction, cyanosis that disappears with O2, slight decrease in air entry, and no grunting. What is the Downes score of the baby?

a)

2

b)

3

c)

4

d)

5

e)

6

40.

What is the function of precipitation in inhibiting the movement of viruses and microorganisms? Precipitation is insoluble?

a)

Opsonization

b)

...

c)

...

d)

...

e)

...

41.

The type of breathing that is fast and deep followed by slow and shallow breathing with periods of apnea for a few moments is called what?

a)

Cheyne-Stokes

b)

Kussmaul

c)

Biot

d)

Normal

e)

Bronchial

42.

The gene that encodes alpha-ketoglutarate dehydrogenase. If polymorphism occurs in that gene, what happens?

a)

Fat accumulation

b)

Increased homocysteine

c)

Methionine accumulation

d)

Decreased homocysteine

e)

...

43.

If there is an accumulation of air in the pleural cavity, what will the percussion sound be?

a)

Hyperresonant

b)

Resonant

c)

Dull

d)

Tympanic

e)

Normal

44.

If there is a mass in the lung, what will the percussion sound be?

a)

Resonant

b)

Hyperresonant

c)

Tympanic

d)

Dull

e)

Normal

45.

If there is blood in the pleural cavity, what will the percussion sound be?

a)

Resonant

b)

Hyperresonant

c)

Tympanic

d)

Dull

e)

Normal

46.

Antibodies can bind to antigens through contact between paratopes and epitopes. For the production of monoclonal antibodies, what is the best type of antigen?

a)

Unideterminant and univalent

b)

Unideterminant and multivalent

c)

Polydeterminant and multivalent

d)

Multideterminant and multivalent

e)

Multideterminant and univalent

47.

What is meant by negative ictus cordis?

a)

Systolic retraction inward and diastolic retraction outward

b)

Systolic retraction outward and diastolic retraction inward

c)

Inspiration retraction inward and expiration retraction outward

d)

Expiration retraction outward and expiration retraction inward

e)

Inspiration and expiration retraction inward

48.

What is the appropriate examination for the disease?

a)

Shifting dullness

b)

Ballotement

c)

Murphy sign

d)

Lasiq sign

e)

...

49.

What examination was performed?

a)

Undulation

b)

Shifting dullness

c)

Murphy

d)

Cullens

e)

Down

50.

Monoclonal antibodies are antibodies obtained by what method?

a)

Fusing immune cells with cancer cells

b)

Dissolving immune cells with cancer cells

c)

Crossbreeding immune cells with cancer cells

d)

Combining immune cells with cancer cells

e)

...

51.

Position of the bone laterally:

a)

Thoracic scoliosis

b)

Lordosis

c)

Kyphosis

d)

Lumbar scoliosis

e)

...

52.

What does the doctor assess during thorax inspection to evaluate dynamic conditions?

a)

Location of the cardiac impulse

b)

Respiratory rate

c)

Venectasia

d)

Shape of the thorax

53.

Which type of malignant tumor is currently the number one killer in both men and women?

a)

Lung

b)

Intestine

c)

Skin

d)

Liver

e)

Prostate

54.

What should be examined if the doctor suspects a genetic polymorphism in a patient who had an acute myocardial infarction despite taking clopidogrel?

a)

CYP2C9

b)

CYP2C19

c)

CYP2E1

d)

CYP2D6

e)

CYP2A6

55.

Which stage of gene therapy involves PCR and RFLP techniques?

a)

Making copies of the normal gene

b)

Identifying the gene causing the disorder

c)

Inserting the vector into the target cell

d)

Inserting the gene copy into the vector

e)

Activating the gene for transcription and translation

56.

What happens when rifampicin is given together with phenytoin, which is a CYP2C12 substrate?

a)

Phenytoin metabolism slows down

b)

Phenytoin metabolism speeds up

c)

Rifampicin metabolism slows down

d)

Rifampicin metabolism speeds up

e)

No metabolism of both drugs occurs

57.

What is the characteristic of the variable region of antibodies?

a)

Has 2 light chain fragments with a molecular weight of 25,000 daltons

b)

Has 2 heavy chain fragments with a molecular weight of 50,000-70,000 daltons

c)

Has 2 types of fragments, kappa and lambda

d)

Functions as a crystallizable fragment

e)

Can recognize various types of antigens

58.

Which mechanism of the hallmark of cancer can be treated with VEGF inhibitors?

a)

Resisting cell death

b)

Inducing angiogenesis

c)

Evading growth suppressors

d)

Avoiding immune destruction

e)

Sustaining proliferative signaling

59.

What does the image show?

a)

Facies leonina

b)

Myxedema

c)

Nephrotic syndrome

d)

Malar rash

e)

Scleroderma

60.

What amino acid replaces glycine in k-ras colon carcinoma?

(a)  

61.

What does the image show?

a)

Facies leonina

b)

Myxedema

c)

Nephrotic syndrome

d)

Malar rash

e)

Scleroderma

62.

What is the amino acid substitute for glycine in k-ras colon carcinoma?

a)

Valine

b)

Arginine

c)

Cysteine

d)

Lysine

e)

Serine

63.

When talking about monoclonal antibodies, what is the correct classification?

a)

Based on specificity

b)

Based on chemical properties

c)

Based on T cell dependence

d)

Based on epitopes

e)

Based on paratopes

64.

What virus causes cervical cancer?

a)

Hepatitis B virus

b)

Hepatitis C virus

c)

Epstein-Barr virus

d)

Human papillomavirus

e)

HTLV-1

65.

If the mother of the child forgets the last menstrual period, what can be used?

a)

New Ballard score

b)

APGAR score

c)

Ross score

d)

DNA transfontanela

e)

Ultrasound

66.

What are the characteristics of a premature baby?

a)

Palmar creases less than 1/3

b)

Plantar creases less than 1/3

c)

Thin lanugo

d)

Size of mammary papilla 5-10 mm

e)

...

67.

What is the advantage of polyclonal antibodies?

a)

Requires few test animals

b)

Can be produced in large quantities

c)

Very specific

d)

Meets diagnostic needs

e)

...

68.

What is the hybridoma technique?

a)

Combining immune cells and cancer cells

b)

Dissolving immune cells and cancer cells

c)

Mating immune cells and cancer cells

d)

Splitting immune cells and cancer cells

e)

69.

What is the term for eyelids that cannot close completely, with narrowed palpebral fissure?

a)

Strabismus

b)

Lagophthalmos

c)

Myasthenia gravis

d)

Ptosis

e)

Palpebral edema

70.

What is the rapidly enlarging lymph node associated with Burkitt Lymphoma?

a)

MYC translocation

b)

p53 overexpression

c)

BRCA-1 gene mutation

d)

RAS overexpression

e)

SIS translocation

71.

What is the diagnosis for a 47-year-old male who fell and has decreased consciousness?

a)

Alloanamnesis and physical examination

b)

Autoanamnesis and supporting examination

c)

Autoanamnesis, alloanamnesis, and physical examination

d)

Autoanamnesis, family history, and supporting examination

e)

Autoanamnesis, alloanamnesis, physical examination, and supporting examination

72.

In ovarian cancer inherited by daughters, which gene mutation occurs?

a)

MYC

b)

APC

c)

BRCA1 and BRCA2

d)

K-Ras

e)

p53

73.

From the photo below, what can you identify as one characteristic of Fragile X Syndrome?

a)

Large protruding ears

b)

Slanted eyes

c)

Sparse/thin eyebrows

d)

Large front teeth

e)

Rounded chin

74.

What component is needed but not stored long in body cells?

a)

Oxygen

b)

H2O

c)

Carbohydrates

d)

Fats

e)

Proteins

75.

What is the positive sign of examination for pain in the right ICS VI?

a)

Psoas

b)

Ludwig

c)

Murphy

d)

Rovsing

e)

...

76.

ersimpan lama di dalam sel tubuh adalah.....

a)

oksigen

b)

H2O

c)

karbohidrat

d)

lemak

e)

protein

77.

Nyeri tekan di ICS VI kanan, tanda positif pemeriksaan......

a)

psoas

b)

ludwig

c)

murphy

d)

rovsing

e)

hipocrates

78.

Terdapat bercak hitam di perut pada bagian umbilikus dan sekitar...

a)

puddle sign

b)

cullen sign

c)

grey turner

d)

murphy sign

e)

chevoteck sign

79.

Organ dikategorikan dalam satu sistem berdasarkan...

a)

regio anatomi

b)

posisi anatomi

c)

tujuan fungsi

d)

jenis sel

e)

sifat jaringan

80.

Elektroforesis polimorfisme menggunakan pita dna berjumlah...

a)

Gambaran 1 pita dna

b)

2 pita dna

c)

3 pita dna

d)

4 pita dna

e)

Tidak ada pita dna

81.

Sekuen dna pendek dan berulang (10x)

a)

PCR

b)

VNTR

c)

RFLP

d)

Akson

e)

Intron

82.

(rflp) Diketahui dna Tn. A dan Tn. B, setelah diberi enzim restriksi; DNA Tn. A jadi 3 pita sedangkan DNA Tn. B 1 pita (tidak terpotong) ....

a)

enzim retriksi mengenali 2 titik di DNA Tn. A

b)

enzim restriksi mengenali 3 titik di DNA Tn. A

c)

enzim restriksi mengenali 2 titik di DNA Tn. B

d)

....

e)

....

83.

Dokter yg memeriksa mendiagnosis pasien sebagai edema paru. bagaimana gejala batuk yg terjadi pada kasus tersebut?

a)

batuk disertai frothy pink tinged sputum

b)

batuk kering

c)

batuk berdahak

d)

batuk kering lalu berdahak

e)

....

84.

Tubuh mengatur homeostasis (kadar gula) dengan cara...

a)

negative feedback

b)

positive feedback

c)

stimulasi

d)

....

e)

....

85.

Laki-laki achondroplasia, jika punya anak, kemungkinan berapa persen anaknya sakit

a)

25%

b)

50%

c)

75%

d)

0

e)

100%

86.

Trauma pada vaskular akan menyebabkan perubahan pada?

a)

afterload

b)

preload

c)

diameter vaskuler

d)

kontraktilitas

e)

....

87.

Keluhan yang hubungannya dengan multisistem adalah..

a)

demam

b)

batuk

c)

pilek

d)

diare

e)

pusing

88.

Organ sensoris yang berperan dalam mengenal lingkungan luar dan dalam adalah

a)

reseptor

b)

afferen

c)

efferent

d)

sistem limbik

e)

nukleus neural

89.

Mekanisme mana dari Hallmark of Cancer yang dapat diterapi dengan EFGR inhibitor?

a)

Resisting Cell Death

b)

Inducing Angiogenesis

c)

Evading Growth Supressors

d)

Avoiding Immune Destruction

e)

Sustaining Proliferative Signaling

90.

Apabila terjadi inhibisi aktivasi IRFs, proses di bawah ini yang terganggu bahkan tidak terjadi....

a)

Transduksi sinyal

b)

Sintesa rRNA

c)

Sintesa tRNA

d)

Sintesa mRNA

e)

Transformasi

91.

Mutasi delesi gen CFTR yang berisi kode untuk membran glikoprotein menghasilkan protein yang tidak mengalami glikosilasi pada Cystic Fibrosis. Protein tidak dapat melipat dengan benar dan itu tidak terekspresi pada permukaan. Pasien tidak mampu mempertahankan elektrolit transportasi masuk dan keluar dari sel. Sekresi lendir tebal, infeksi paru dan obstruksi, " Salty Skin". Kelainan ini terjadi selama proses

a)

Post translation : protein folding

b)

Transcription : poly adenylation signal

c)

Post translation : glycosylation

d)

Post translation : protein targeting

e)

Translation : polypeptida chain

92.

Poly (A) tail diketahui merupakan salah satu proses

a)

Menghasilkan mRNA matur

b)

Inisiasi translasi

93.

What is the result of the Poly (A) tail process?

a)

Produces mature mRNA

b)

Initiates translation

c)

Located at the 5' mRNA

d)

Makes mRNA unstable

e)

Processed in the cytoplasm

94.

How will the electrophoresis look if both alleles at nucleotide position 641 experience polymorphism?

a)

324 bp

b)

324 bp, 210 bp and 114 bp

c)

210 bp and 114 bp

d)

324 bp and 210 bp

e)

641 bp, 210 bp

95.

What test is it?

a)

Shifting dullness

b)

Rovsing sign

c)

Rebound tenderness

d)

Obturator sign

e)

Costovertebral tenderness

96.

What can be found from genetic examination related to inflammation triggers in the body?

a)

Expression of inflammatory genes increases in the MUFA group

b)

Expression of inflammatory genes increases in the SFA group

c)

Expression of anti-inflammatory genes increases in the SFA group

d)

Expression of anti-inflammatory genes decreases in the MUFA group

e)

Expression of anti-inflammatory genes decreases in the SFA group

97.

Where is the left border of the heart located?

a)

ICS 5 midclavicular line left

b)

ICS 4 midclavicular line left

c)

ICS 6 parasternal line left

d)

ICS 4 parasternal line left

e)

ICS 5 parasternal line left

98.

What is the name of the additional breath sound that is interrupted due to narrowing of the airway?

a)

Dry rhonchi

b)

Wet rhonchi

c)

Wheezing

d)

Vesicular

e)

Stridor

99.

What is the cause of the high fever in a 2-year-old girl who has been admitted to the ER?

a)

Endogenous IL-1

b)

Endogenous IL-2

c)

Exogenous IL-0

d)

Exogenous IFN Alpha

e)

Exogenous lipopolysaccharide

100.

Which organ system directly maintains the body's fluid balance?

a)

Neuronal

b)

Cardiovascular

c)

Urinary

d)

Hormonal

e)

Integument

101.

What about the FTO gene?

a)

Related to body fat mass

b)

Individuals with heterozygous alleles gain weight more easily

c)

Individuals with homozygous AA alleles have no appetite

d)

Encodes an abnormal protein

e)

Increases skeletal muscle mass

102.

When does bowel sound decrease?

a)

Peritonitis

b)

Obstructive ileus

c)

Paralytic ileus

d)

Necrolithiasis

103.

What is the condition when the intestines are noisy?

a)

Peritonitis

b)

Ileus obstruction

c)

Ileus paralytic

d)

Necrolitis enteroticans

e)

Post-operative

104.

If Rifampicin is given together with Phenytoin, which is a substrate of CYP2C12, then....

a)

The metabolism of Phenytoin will slow down

b)

The metabolism of Phenytoin will speed up

c)

The metabolism of Rifampicin will slow down

d)

The metabolism of Rifampicin will speed up

e)

The metabolism of both drugs will not occur

105.

A mutation occurs at the Normal Cleavage Site Factor of blood coagulation and causes excessive production of that coagulation factor. This leads to Hypercoagulability. Increased risk of DVT, PE. Pathological: The consequences of this Thrombophilia disease are caused by defects in transcription at the time of...

a)

Immature mRNA synthesis

b)

Intron splicing

c)

Alternative splicing

d)

Poly(A) adenylation signal

e)

5' mRNA cap

106.

What is the correct diagnosis according to the image?

a)

Becker muscular dystrophy

b)

Duchenne muscular dystrophy

c)

Fragile X syndrome

d)

Huntington disease

e)

Neurofibromatosis type 1

107.

Nn. B came to the doctor complaining that for the past three years he has experienced....., three months ago he often coughed and sweated at night, and one week ago he experienced.... The history of the disease started from...

a)

3 years ago experienced..., 3 months ago experienced..., one week ago experienced....

b)

one week ago experienced...., 3 months ago experienced..., 3 years ago experienced...

c)

...

d)

...

e)

...

108.

What examination is shown in the image below?

a)

Bimanual

b)

...

c)

Shifting dullness

d)

Rovsing sign

e)

Undulation

109.

At what Korotkoff sound does diastolic appear?

a)

I

b)

II

c)

III

d)

IV

e)

V

110.

A physical examination of a child shows body disproportion with a relatively larger head. The suspected diagnosis for this child is...

a)

Achondroplasia

b)

Duchenne Muscular Dystrophy

c)

Macrocephaly -> hydrocephalus

d)

...

e)

...

111.

Polymorphism in CYP2E19 will provide an enhanced metabolizer effect on the patient. Rifampicin when given together with phenytoin will cause...

a)

Phenytoin metabolism to be inhibited

b)

Phenytoin metabolism to be accelerated

c)

Rifampicin metabolism to be slowed down

d)

Rifampicin metabolism to be accelerated

e)

No metabolism of both drugs occurs

112.

A stop codon causes the ribosome to stop during the translation process. This results in...

a)

No polypeptide/amino acid formation

b)

Shortening of the polypeptide chain

c)

Lengthening of the polypeptide chain

d)

The translation process is unaffected and continues

113.

What replaces glycine in H ras/K ras (I forgot the main point between these two)...

a)

Valine

b)

Alanine

c)

Methionine

d)

Arginine