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WorksheetsProstaglandins Quiz
Total questions: 15
Worksheet time: 8mins
What are autocoids primarily characterized by?
High molecular weight proteins
Long-distance transport in the bloodstream
Local action at the site of synthesis
Systemic hormone action
Which of the following is NOT classified as an amine autocoid?
Histamine
Bradykinin
Serotonin
5 HT
What is the primary role of COX-1 in the body?
Regulates blood pressure
Involved in pain sensation
Constitutive in most cells
Inducible during inflammation
Which prostaglandin is primarily responsible for vasodilation in vascular beds?
TXA2
PGF2α
PGE2
PGI2
What is the effect of PGE2 on the gastrointestinal tract?
Increases gastric acid secretion
Decreases mucus production
Promotes secretory diarrhea
Inhibits water absorption
How do NSAIDs affect prostaglandin synthesis?
Enhance synthesis
Inhibit synthesis
Have no effect
Only affect COX-1
Which prostaglandin is used to maintain the patency of the ductus arteriosus?
Alprostadil (PGE1)
Dinoprostone (PGE2)
Latanoprost (PGF2α)
Carboprost (PGF2α)
What is the primary action of TXA2 in the cardiovascular system?
Promotes vasodilation
Reduces blood pressure
Inhibits platelet aggregation
Stimulates platelet aggregation
Which of the following is a therapeutic use of Misoprostol?
Induction of labor
Treatment of hypertension
Management of asthma
Cervical dilation in surgery
What is the effect of PGE2 on renal function?
Decreases renin release
Inhibits renal vasodilation
Promotes sodium retention
Facilitates water clearance
Which prostaglandin is known for its role in initiating labor?
PGF2α
PGE2
PGI2
TXA2
What is a common adverse effect of prostaglandin analogs?
Decreased heart rate
Increased appetite
Weight gain
Nausea and vomiting
Which of the following prostaglandins is primarily involved in bronchoconstriction?
TXA2
PGI2
PGE2
PGF2α
What is the mechanism of action of glucocorticoids in relation to prostaglandins?
Enhance prostaglandin synthesis
Promote annexin production
Inhibit COX-1 activity
Increase arachidonic acid release
Which prostaglandin is primarily responsible for the contraction of the uterus?
PGF2α
TXA2
PGI2
PGE2
