Which types of drugs work through physical or chemical reactions rather than through receptor binding? (select all that apply)

Which time frame is appropriate for obtaining a peak level from a patient receiving intravenous vancomycin?

A patient is prescribed an increased dose of a drug to improve control of their blood pressure. A week later, there is no change in the patient’s blood pressure (BP). Which phase of the dose-response curve might this reflect?

When providing care for a person who has stopped taking a drug with a half-life of 4 hours, how long will it take for 94% of the drug to leave the body?

Which of the four receptor families regulates protein synthesis?

Which drug(s) classes interact adversely with cheeses? (select all that apply)

Which route of administration provides rapid onset of delivery to enhance safety and efficacy?

The liver metabolizes drugs into which component for renal excretion?

14. Only ___ of the 12 closely related cytochrome P450 enzyme families metabolize drugs.

Moves drugs from blood to urine

Lipid-soluble drugs move back into the blood

“Pumps” for organic acids and bases move drugs from blood to urine

Which organ accounts for most drug excretion, thereby limiting the duration of action of many drugs?

Drugs are excreted by which routes? (select all that apply)

Which route of drug administration is most likely to be reversible?

Which route of drug administration delivers drugs directly to the tissue where they exert their actions?

Which conditions decrease blood flow to tissues, thereby reducing the effectiveness of drug therapy? (select all that apply)

The nurse knows that warfarin is 99% protein bound, whereas bupropion is 84% protein bound. If both drugs are administered concurrently, which events could occur? (select all that apply)

To safely administer drugs, nurses must understand that only certain drugs can cross the blood-brain barrier (BBB), including those that are highly lipid soluble and of low molecular weight. Which drug can cross the BBB?

Which routes of administration can be used to avoid the first-pass effect? (select all that apply)

Which factors alter drug metabolism in older adults? (select all that apply)

Kidney stones and urinary obstruction alter which pharmacokinetic principle?

Certain drugs must undergo which process before enterohepatic recirculation can occur?

Drugs with which property are excreted in breast milk?

Which route of drug administration bypasses the first-pass effect in the liver?

Which pharmacokinetic process is most affected in patients with severe liver disease?

Which property increases a drug's likelihood of being reabsorbed from the renal tubules back into the bloodstream?