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Worksheets

Varieties of macromolecules

Total questions: 48

Worksheet time: 24mins

Name
Class
Date
1.

Which of the following is a variety of macromolecule?

a)

Protein

b)

Lipid

c)

Sugar

d)

Peptide

2.

Which of the following is NOT a variety of macromolecule?

a)

DNA

b)

RNA

c)

Peptide

d)

Protein

3.

Fill in the blank: ______, DNA, and RNA are varieties of macromolecules.

a)

Proteins

b)

Lipids

c)

Carbohydrates

d)

Vitamins

4.

Complexes such as protein-protein and protein-DNA/RNA are considered as varieties of ______.

a)

macromolecules

b)

micromolecules

c)

organelles

d)

ions

5.

Lipids, peptides, sugars, etc are categorized as ______ macromolecules.

a)

non

b)

ionic

c)

metallic

d)

radioactive

6.

Our discussion is more focused on ______ molecules.

a)

protein

b)

carbohydrate

c)

lipid

d)

nucleic acid

7.

Deoxyribonucleic acid, DNA, consists of two long polymers of simple units called nucleotides. Which of the following is NOT a nucleotide found in DNA?

a)

Cytosine

b)

Guanine

c)

Adenine

d)

Uracil

8.

Which nucleotide is present in RNA but not in DNA?

a)

Thymine

b)

Uracil

c)

Adenine

d)

Guanine

9.

Fill in the blank: The sequence of four bases along the backbone encodes information, or the genetic code. The four bases in DNA are Cytosine, Guanine, Adenine, and _______.

a)

Thymine

b)

Uracil

c)

Arginine

d)

Serine

10.

RNA has the same nucleotides as DNA except that Thymine is replaced by Uracil.

a)

True

b)

False

11.

What is the genetic code?

a)

A) A series of codons in part of a mRNA molecule

b)

B) A series of proteins in a DNA molecule

c)

C) A sequence of amino acids in a protein

d)

D) A type of carbohydrate in a cell

12.

Each codon consists of ______ nucleotides.

a)

three

b)

two

c)

four

d)

five

13.

Each codon in mRNA usually represents a single ______.

a)

amino acid

b)

nucleotide

c)

sugar

d)

fatty acid

14.

Refer to the diagram of RNA. How many nucleotides are present in one codon?

a)

One

b)

Two

c)

Three

d)

Four

15.

What are proteins composed of?

a)

One or more polypeptides

b)

One or more carbohydrates

c)

One or more lipids

d)

One or more nucleic acids

16.

The sequence of amino acids in a protein is defined by the sequence of a ________, which is encoded in the genetic code.

a)

gene

b)

enzyme

c)

ribosome

d)

chromosome

17.

Proteins are the molecular building block of life.

a)

True

b)

False

18.

Protein molecules are ________-dimensional.

a)

three

b)

one

c)

two

d)

four

19.

What is the central atom in the structure?

a)

Cα (alpha carbon)

b)

O (oxygen)

c)

N (nitrogen)

d)

H (hydrogen)

20.

Refer to the diagram of the General Amino Acid Structure at pH 7.0. Which group is present on the left side of the central carbon?

a)

Carboxyl group

b)

Amino group

c)

Hydrogen atom

d)

R group

21.

Refer to the diagram of the General Amino Acid Structure at pH 7.0. The group labeled 'COO-' is known as the ________ group.

a)

carboxyl

b)

amino

c)

hydroxyl

d)

methyl

22.

What does the 'R' group represent in the structure?

a)

The variable side chain that differs between amino acids

b)

The carboxyl group in all amino acids

c)

The amino group in all amino acids

d)

The hydrogen atom attached to the alpha carbon

23.

Which statement is true about L- and D- amino acids?

a)

L-amino acid rotates plane polarized light clockwise

b)

D-amino acid rotates plane polarized light counter-clockwise

c)

L-amino acid rotates plane polarized light counter-clockwise

d)

Both rotate light in the same direction

24.

Which of the following amino acids is hydrophobic?

a)

Alanine

b)

Serine

c)

Glutamine

d)

Asparagine

25.

Fill in the blank: The one-letter abbreviation for Phenylalanine is ___

a)

F

b)

P

c)

A

d)

L

26.

Which amino acid has the one-letter abbreviation 'L'?

a)

Leucine

b)

Isoleucine

c)

Proline

d)

Valine

27.

Hydrophobic amino acids tend to avoid water and associate with each other to minimize their contact with water or polar side chains.

a)

True

b)

False

28.

Which of the following amino acids is represented by the abbreviation 'Arg'?

a)

Arginine

b)

Aspartic acid

c)

Glutamic acid

d)

Serine

29.

Fill in the blank: The abbreviation for Glutamine is _____

a)

Gln

b)

Glu

c)

Gly

d)

Gle

30.

What does it mean for an amino acid to be amphipathic?

a)

Having both polar and nonpolar character and therefore a tendency to form interfaces between hydrophobic and hydrophilic molecules.

b)

Being exclusively hydrophobic and unable to interact with water.

c)

Having only polar character and always dissolving in water.

d)

Being a charged molecule that cannot interact with lipids.

31.

Which of the following amino acids is amphipathic? (Refer to the diagram showing the structures of Lysine, Tyrosine, Methionine, and Tryptophan.)

a)

Lysine

b)

Tyrosine

c)

Methionine

d)

Tryptophan

32.

Fill in the blank: The one-letter code for Tyrosine is ___

a)

Y

b)

T

c)

R

d)

S

33.

Fill in the blank: The three-letter abbreviation for Methionine is ___

a)

Met

b)

Mth

c)

Mtn

d)

Mte

34.

Fill in the blank: The amino acid represented by the one-letter code W is ___.

a)

Tryptophan

b)

Tyrosine

c)

Taurine

d)

Threonine

35.

In the peptide chain diagram, what type of bond connects the carbon of one amino acid to the nitrogen of the next amino acid?

a)

Hydrogen bond

b)

Ionic bond

c)

Peptide bond

d)

Disulfide bond

36.

Which of the following statements is true?

a)

Bond rotation does not affect protein folding

b)

Bond rotation determines protein folding, 3D structure

c)

Bond rotation is not important for proteins

d)

Bond rotation only affects carbohydrates

37.

Double bond disallows rotation.

a)

True

b)

False

38.

What does the torsion angle (dihedral angle) measure in a molecule? Fill in the blank: The torsion angle (dihedral angle) measures the orientation of ______ linked atoms in a molecule.

a)

four

b)

two

c)

three

d)

five

39.

Refer to the diagram titled 'Backbone Torsion Angles of a protein'. Which torsion angle is represented by the symbol φ (phi)?

a)

The angle around the N-Cα bond

b)

The angle around the Cα-C' bond

c)

The angle around the C'-N bond

d)

The angle around the Cα-side chain bond

40.

The torsion angle ψ (psi) is associated with which bond?

a)

N-Cα

b)

Cα-C'

c)

C'-N

d)

Cα-side chain

41.

Refer to the diagram titled 'Backbone Torsion Angles of a protein'. The torsion angle ω (omega) is associated with the bond between _______.

a)

C'-N

b)

N-Cα

c)

Cα-C'

d)

Cα-R

42.

What is the atomic connection for the phi (ϕ) angle in a peptide?

a)

N-Cα

b)

Cα-CO

c)

C-N

d)

N-CO

43.

What is the atomic connection for the omega (ω) angle in a peptide?

a)

N-Cα

b)

Cα-CO

c)

C-N

d)

N-CO

44.

What is the dihedral angle ω in proteins?

a)

Rotation about the peptide bond, namely Cα1-{C-N}-Cα2

b)

Rotation about the side chain

c)

Rotation about the disulfide bond

d)

Rotation about the hydrogen bond

45.

Which backbone torsion angles are flexible and allow rotation?

a)

A) φ and ψ

b)

B) Only φ

c)

C) Only ψ

d)

D) None

46.

Fill in the blank: The rotation of φ and ψ angles in a given amino acid residue is limited due to ________ hindrance.

a)

steric

b)

electrostatic

c)

hydrogen bond

d)

covalent

47.

Refer to the diagram. Which angles in the polypeptide backbone are labeled as φ and ψ?

a)

The angles between N-Cα and Cα-C

b)

The angles between C-N and N-Cα

c)

The angles between Cα-C and C-N

d)

The angles between O-H and N-H

48.

The Omega angle in a protein backbone is typically fixed and does not rotate freely like PHI and PSI.

a)

True

b)

False