WorksheetsTuberculosis and Anti-Tuberculosis Drugs Quiz
Total questions: 25
Worksheet time: 13mins
What is the major health problem caused by Mycobacterium tuberculosis?
Acute respiratory infection
Chronic granulomatous disease
Viral pneumonia
Fungal infection
How many deaths per year are attributed to tuberculosis in Indonesia?
250,000
500,000
125,000
1 million
Which drug is NOT part of the intensive phase treatment for tuberculosis?
Streptomycin
Ethambutol (EMB)
Rifampicin (RIF)
Isoniazid (INH)
What is the recommended daily dose of Isoniazid (INH) for tuberculosis treatment?
20 mg/kg
15 mg/kg
5 mg/kg
10 mg/kg
Which drug can replace Rifampicin (RIF) in certain situations?
Ethambutol (EMB)
Rifabutin (RBT)
Streptomycin
Isoniazid (INH)
What is the mechanism of action of Isoniazid (INH)?
Inhibits mycolic acid synthesis
Inhibits RNA synthesis
Inhibits protein synthesis
Inhibits DNA replication
Which drug is known to inhibit DNA-dependent RNA polymerase?
Isoniazid
Rifampicin
Ethambutol
Streptomycin
What is the primary resistance mechanism for Rifampicin?
Mutation of KatG
Mutation of rpoB
Efflux pump
Mutation of inhA
Which drug is primarily used for drug-resistant tuberculosis?
Ethambutol
Levofloxacin
Rifampicin
Isoniazid
What is the maximum daily dose of Rifampicin?
300 mg
750 mg
600 mg
450 mg
Which drug is a first-line anti-tuberculosis medication introduced in 1961?
Rifampicin
Streptomycin
Isoniazid
Ethambutol
What is the mechanism of action of Pyrazinamide?
Inhibits protein synthesis
Inhibits mycolic acid synthesis
Disrupts membrane transport
Inhibits DNA replication
Which drug is known for causing peripheral neuropathy as an adverse effect?
Rifampicin
Streptomycin
Isoniazid
Ethambutol
What is the primary use of Streptomycin?
First-line treatment for TB
Second-line treatment for TB
Treatment for viral infections
Treatment for fungal infections
Which drug is a fluoroquinolone used in tuberculosis treatment?
Ethambutol
Isoniazid
Rifampicin
Levofloxacin
What is the half-life of Rifampicin?
12-24 hours
6-10 hours
2-5 hours
1-2 hours
Which drug is contraindicated in liver disease?
Streptomycin
Ethambutol
Rifampicin
Isoniazid
What is the mechanism of action of Ethambutol?
Inhibits mycolic acid synthesis
Inhibits arabinosyltransferase
Inhibits protein synthesis
Inhibits DNA replication
Which drug is known for causing orange-red urine?
Ethambutol
Streptomycin
Isoniazid
Rifampicin
What is the recommended daily dose of Ethambutol?
15 mg/kg
10 mg/kg
5 mg/kg
20 mg/kg
Which drug is used for the treatment of latent tuberculosis infection?
Ethambutol
Rifampicin
Isoniazid
Streptomycin
What is the primary adverse effect of Streptomycin?
Ototoxicity
Nephrotoxicity
Gastrointestinal upset
Hepatotoxicity
Which drug is a second-line treatment for tuberculosis?
Kanamycin
Ethambutol
Rifampicin
Isoniazid
What is the mechanism of action of Fluoroquinolones?
Inhibit DNA gyrase
Inhibit RNA polymerase
Inhibit mycolic acid synthesis
Inhibit protein synthesis
Which drug is known to cause hepatotoxicity in high doses?
Ethambutol
Rifampicin
Streptomycin
Isoniazid
