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WorksheetsMBBS Multiple Choice Questions – Extraction
Total questions: 80
Worksheet time: 40mins
Characteristics of fungi would include
Heterotrophism
Autotrophism
Mostly pathogenic
Possess chlorophyll
Arthroconidia is typical to?
Paracoccidioides brasiliensis
Candida albicans
E. coli
Coccidioides immitis
The histologic review of a biopsy of a bone of a migrant from Guatemala revealed a broad-based yeast. What is the likely pathogen?
Blastomyces dermatitidis
Paracoccidioides brasiliensis
Candida albicans
Coccidioides immitis
A rusty red-currant jelly sputum from an alcoholic 42-year-old woman would suggest which of the pathogens
E. coli
Klebsiella pneumoniae
Aspergillus spp.
None of the above
A 3-year-old with patchy fungating mass on the head. Which of the following conditions could be entertained except?
Tinea capitis
Favus
Kerion
Scutula
Which of the following can be matched accordingly?
Soft chancre — Candida albicans
Hard chancre — Haemophilus ducreyi
Tertiary syphilis — condyloma acuminata
Latent syphilis — VDRL positive
The following drugs are useful against MDR-TB in a 55-year-old female commercial sex worker
Bedaquiline
Ciprofloxacin
Kanamycin
Rifampicin
The infection prevention protocol useful for MDR-TB in a 24-year-old school teacher would include
Source isolation
Protective isolation
Bimodal isolation
None of the above
Mrs I. Z is an emigrant from Iran and presents with vitiligo-like skin infection. However, the Medical Microbiologist suspects a spirochaetal disease. What is the possible disease condition?
Yaws
Bejel
Pinta
Syphilis
The most notable event of an invasive fungal infection is?
Tissue damage and absence in sterile body site
Presence in normally sterile site only
Tissue damage only
None of the above
Serological identification of Candida spp. can include
C-reactive protein
Presepsin
Mannan
Procalcitonin
Sepsis management would involve the following except:
Oxygen administration
Source control of infection
Intravenous fluid administration
Use of empiric enteral antibiotics
A typical clinical picture of cryptococcal meningitis will be
Headaches in 80% of cases
Meningism in 50% of cases
Headache, meningism and low mentation in 60–80% of cases
Low mentation and headaches in 100% of cases
The signal amplification method will include all except
Use of nucleic acid probes
Use of hybrid capture
Fluorescent in-situ hybridization
None of the above
The known phases of pathology of Strongyloides stercoralis will include all but
Skin
Intestine
Lungs
Eyes
Systemic mycoses can infect through the following routes
Skin
Eye
Mucous membrane
Visceral
Pre-extensive drug resistant tuberculosis shall be defined as
Resistance to isoniazid, rifampicin and moxifloxacin
Resistance to isoniazid, kanamycin and moxifloxacin
Resistance to isoniazid, rifampicin and rifampentine
Resistance to isoniazid, rifampicin and linezolid
Lyme’s disease can affect the nervous system to cause
Encephalitis
Neuroborreliosis
Meningitis
Subdural haematoma
Enzymes responsible for anaerobiosis can include
Catalase
Dehydrogenase
Elastase
Collagenase
A 3-year-old boy presenting with golden crust over the lower lips with a reddened slapped cheek. The following would be considered as the causation
Staphylococcal skin infection
Streptococcal lip infection
Endotoxaemia
Exotaemia
The following organism cannot cause human infections
Viroids
Bacteria
Helminthes
Viruses
This is not true about Viruses
Made up of DNA and RNA
Made up of DNA genome only
Made up of RNA genome only
Surrounded by a protein coat
Resolving power of a microscope is
To magnify images
To view images
To resolve objects
To distinguish two closely spaced objects as separate
Medically important bacteria that can be seen by Gram stain
E. coli
Mycoplasma pneumoniae
M. tuberculosis
Treponemapallidum
The following an example of passive form of immunity
Tetanus toxoid injection
Anti-tetanus serum injection
Ingestion of oral polio vaccine
Family planning injection
Components of adaptive immunity except
Found only in jawed vertebrates
Cell Mediated immunity
Humoral immunity
Gut E. coli
The following is true of cultural characteristic of Staphylococcus aureus
It is a strict anaerobe
It is a strict aerobe
It grows readily on simple media
It does not tolerate PH of 7.4
Toxin produced by staphylococcus aureus
Nucleases
Lipases
Proteases
Toxic shock syndrome toxin
One of the following disease will not manifest with difficulty in swallowing
Tetanus
Pharyngitis
Diphtheria
Gastritis
Complications of chlamydia genital infection does not include
Higher risk of ectopic pregnancy
Chronic abdominal pain
Cervical cancers
Sterility
Diagnosis of chlamydial infections include the following except
Detection of extra cytoplasmic inclusion bodies
Geimsa stain
Cell culture
Antigen detection using ELISA
The following is a diphtheroid
Corynebacterium diphtheria
C. gravis
Non-diphtherial Corynebacteria
C. mitis
These are species of plasmodium except
P pivax
P ovale
P malariae
P malizeaser
An individual infected with malaria parasite through blood transfusion does not have in his body
Hypnozoite
Trophozoite
Schizont
Gametocyte
Causes cerebral malaria in children
Plasmodium falciparum
Plasmodium ovale
Plasmodium malariae
Plasmodium vivax
The following is true of prion diseases except
Prions are infectious proteinaceous material
Scrapie is a prion disease of sheep
Scrapie results from degeneration of the CNS
Prion protein only has RNA but no DNA
The following are prion diseases primary to humans except
Kuru
Creutzfeldt–Jakob disease (CJD)
Gerstmann–Straussler–Scheinker syndrome (GSS)
Scrapie
HBV post‑vaccination screening test is
HBsAg
HBsAb
HBcAb
HBeAb
The following is not true of bulbar poliomyelitis
Associated with high mortality
1st and 2nd cranial nerves are involved
Paralysis is usually flaccid
Can coexist with spinal paralysis
Naked virus
Include herpesviruses, adenoviruses, picornaviruses and hepadnaviruses
Enveloped surrounding the virus is viral encoded
Usually possess surface glycoprotein which are antigenic
The surface layer is made up of protein
True of Hepatitis B virus except
Member of Hepadnaviridae family
Small, hepatotropic DNA virus that infects only humans in nature
The viral infection can be acute and self‑limited
Extra‑hepatic manifestations is a cell‑mediated immune response
The following is true
Infection with HBV is defined by the presence of HBsAg
About 150 million Hepatitis B virus chronic infections occur globally
Hepatitis B virus belongs to the same family as Epstein–Barr virus
Hepatitis D virus is a DNA virus
One of the following pairs are synonymous
Measles and fifth’s disease
Rubeolla and rubella
Chicken pox and zoster
Roseola infantum and exanthema subitum
The following except one is true of measles
Paramyxoviridae
Morbilli
Inactivated vaccine
Ribavirin
True of chicken pox except
Caused by varicella‑zoster virus
Is highly contagious
Can be best treated with acyclovir after 48 hours of onset of rashes
Lesion is extremely pruritic
Endotoxins are
Toxoidable
Typical of all pathogenic bacteria
Strongly antigenic
Somewhat antigenic
Not true of pathogenic bacteria
Adhesive forces could be nonspecific
Lysogenicity is a common feature
Host cell induced invasiveness is possible
Antigenic heterogeneity is a phenomenon
Most conserved genetic element of bacterial cells
16S rRNA
Plasmid
Episome
Gene
Pathological bases of lipids in the mycobacterial cell except
Granuloma formation
Acid‑fastness
Resistance
Peptidoglycan
ZN stain positive except
Mycobacterium bovis
Streptomyces sp
Nocardia spp.
Corynebacterium diphtheriae
Causative agent of Madura foot
Streptomycetes
Actinomycetes
Peptostreptococcus
Acinetomycetes
Differentiating criteria of Moraxellae from Neisseriae except
DNA base composition
Fatty acid composition
Inability to produce acid from carbohydrates
Haemolysis on blood agar
Antigenic and virulence factor not relevant for Neisseria meningitidis infection
Capsule
Outer membrane proteins
Lipooligosaccharides
Cell wall proteins I and II
Definitive of Neisseria gonorrhoeae urethritis diagnosis
Positive Gram‑negative stain
Positive Gram‑negative diplococci stain
Positive Gram‑negative intracellular biconcave diplococci stain
Positive Gram‑negative extracellular biconcave diplococci stain
Descriptive of the meningitides belt of Africa
Latitudes 4° N to 16° N
Latitudes 4° S to 16° S
Latitudes 4° E to 16° E
Latitudes 4° N to 16° S
Antibiotics stewardship strategy associated with perceived loss of autonomy
Formulary restriction and pre-authorization
Prospective audit with intervention and feedback
Enforcement of antimicrobial order forms use
Streamlining of antimicrobial use
Not correct about both Vibrio cholerae and Helicobacter pylori
Gram negative reaction
Urease production
Motile by flagellation
Oxidase positive
Not true about Pox viruses
Largest known virus
Bricked shape
Non-enveloped
Nearly visible under compound light microscopy
Classic features of adenoviral infections except
Secondary viraemia
Cell mediated and humoral immunity
Latent infection
Transforming infection
Correct about exotoxins secreted by capable Enterobacteriaceae
Polysaccharide in nature
Poor antigenicity
Dose independent effect
Specificity of effects on host cell
Dependoviruses are not
Poxviruses
Defective viruses
Adenoviruses associated
Capable of causing infection in man
Parvovirus B19
Is a positive stranded RNA virus
Notorious for lytic infections
Replicates in the cytoplasm of infected cells
Cause infection with transient low level viraemia
Attributes not unique to poxviruses
Production of more than 100 polypeptide
Replication in the cytoplasm
Naked DNA infectivity
Highly species-specificity
Urethritis pathogen not routinely diagnosed with direct urine microscopy
Chlamydia trachomatis
Neisseria gonorrhoeae
Herpes simplex virus II
Trichomonas vaginalis
Not related to antimicrobial resistance emergence and spread among Enterobacteriaceae
ESBL production
Carbapenemases production
Horizontal genetic element spread by conjugation
Lysosomal enzyme productivity
Which of the following serological test should be performed for the diagnosis of Rickettsia rickettsii from skin biopsy specimen of a rash?
Agglutination test
Enzyme linked immunosorbent assay
Indirect immunofluorescence assay
Complement fixation
A 32-year-old woman visited a primary care clinic with complaints of persistent fatigue, weight loss, recurrent fever and night sweats. She also had frequent yeast infection and upper respiratory tract infections. HIV infection is suspected. Which of the following test is the screening test usually done for HIV?
Western blot
VDRL
PCR or viral load
Enzyme immunoassay
The role of human in the life cycle of Yersinia pestis is
Secondary reservoir
Primary transmission vector
Primary host
Accidental intruder in rat flea cycle
Which is correctly matched
Megaoesophagus — T gambiense
Winterbottom sign — T. cruzi
Romania sign — T rhodesiense
Visceromegaly — L. donovani
Man is intermediate host for
Taenia solium
Malaria
Filarial
Guinea worm
Which of the following statements is NOT correct about the cultural characteristics of Yersinia pestis?
The bacteria can cause pneumonia in humans through airborne droplets
The suitable bacterial growth temperature is room temperature using MacConkey agar
The bacteria are lactose positive
The common source of transmission to humans is through rats
All of the statements given below are correct about the possible clinical presentations of Yersinia pseudotuberculosis infection in humans, EXCEPT
Typhoidal-like illness
Mesenteric lymphadenitis
Erythema nodosum
Arthritis
Bacillus anthracis is a medically important spore-forming rod that may cause the disease anthrax in animals and humans. What are the two important virulence factors of the bacteria?
Capsule and enterotoxins
Exotoxins and enterotoxins
Endotoxins and capsule
Capsule and exotoxins
All of the statements given below about the Yersinia enterocolitica is correct, EXCEPT
The bacteria are gram-negative, non-motile
Consist of bipolar staining property
The most common serotypes causing human gastroenteritis is O:1
Transmission to humans may occur via contaminated food and water
Which of the following Rickettsia spp can cause the following symptoms: Fever, flu, and papulovesicular rash similar to varicella infection?
Rickettsia australis
Rickettsia akari
Rickettsia prowazekii
Rickettsia rickettsii
Acute chagas disease is characterised by
Bubo
Megaintestine
Mega oesophagus
Lymphadenopathy
For swine flu to replicate in the host cell it must carry an enzyme for nucleic acid replication. Which enzyme is this?
RNA-dependent DNA polymerase
DNA-dependent DNA polymerase
RNA-dependent RNA polymerase
DNA-dependent RNA polymerase
All of the following statements regarding Trichomoniasis are true, Except
It is a sexually transmitted disease
Found to be more common in women than in men
The drug for treatment is mebendazole.
A common protozoal infection in the USA
Biological false reaction in VDRL is related to
Lepra bacilli
Corynebacterium diphtheria
Cl.welchi
None of these
Diphtheria toxins are produced from the strains of C.diphtheriae, which are
Encapsulated
Lysogenic for β prophase
Glucose fermenters
Sucrose fermenters
