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Cell cycle and cell biology worksheet

Total questions: 40

Worksheet time: 40mins

Name
Class
Date
1.

What is a chromatid?

a)

A region where microtubules attach

b)

One of two identical copies of a replicated chromosome

c)

A structure that holds homologous pairs together

d)

The DNA-protein complex inside the nucleus

2.

During which phase does the nuclear envelope break down?

a)

Telophase

b)

Prometaphase

c)

Interphase

d)

G2 phase

3.

What happens during G1 phase?

a)

The cell grows and performs normal functions

b)

DNA is replicated

c)

Chromosomes separate

d)

Homologous chromosomes pair

4.

What is cytokinesis?

a)

Replication of DNA

b)

Division of the nucleus

c)

Division of the cytoplasm

d)

Crossing over between chromosomes

5.

Which feature is unique to prokaryotes?

a)

Membrane-bound nucleus

b)

Circular chromosome

c)

Linear DNA strands

d)

Mitosis for cell division

6.

Which phase of mitosis aligns chromosomes in the center?

a)

Prophase

b)

Metaphase

c)

Anaphase

d)

Telophase

7.

Crossing over occurs during which stage?

a)

Metaphase II

b)

Anaphase I

c)

Prophase II

d)

Prophase I

8.

What is a diploid cell?

a)

A cell with one copy of each chromosome

b)

A cell with two copies of each chromosome

c)

A cell with three sets of chromosomes

d)

A cell produced only by bacteria

9.

What is independent assortment?

a)

The pairing of homologous chromosomes

b)

Random orientation of chromosome pairs during meiosis I

c)

Error-free DNA replication

d)

Equal division of cytoplasm

10.

What is nondisjunction?

a)

A type of mutation involving base substitution

b)

Uneven crossing over

c)

Failure of chromosomes to separate properly

d)

Replication of DNA in S phase

11.

What is a genotype?

a)

The genetic makeup of an organism

b)

The physical traits

c)

A type of mutation

d)

A copy of an allele

12.

What is codominance?

a)

One allele blocks another

b)

Both alleles are expressed equally

c)

A blend of traits

d)

Only recessive alleles are expressed

13.

What did Mendel’s Law of Segregation state?

a)

Genes are always inherited together

b)

Allele pairs separate during gamete formation

c)

Dominant alleles mutate more often

d)

Phenotypes always match genotypes

14.

What is a test cross used for?

a)

Determining phenotype

b)

Identifying codominance

c)

Determining an unknown genotype

d)

Increasing genetic variation

15.

What is a locus?

a)

A protein on DNA

b)

A location of a gene on a chromosome

c)

A mutation

d)

A type of allele

16.

What is polygenic inheritance?

a)

Multiple genes influence a single trait

b)

One gene controls multiple traits

c)

A single allele is expressed

d)

Inheritance on sex chromosomes

17.

What type of inheritance pattern involves alleles blending?

a)

Codominance

b)

Incomplete dominance

c)

Polygenic

d)

Sex-linked

18.

What blood type is considered “codominant”?

a)

Type O

b)

Type AB

c)

Type A

d)

Type B

19.

Colorblindness is usually:

a)

Autosomal dominant

b)

X-linked recessive

c)

Codominant

d)

Polygenic

20.

Which structure is responsible for forming the spindle?

a)

Centrioles

b)

Ribosomes

c)

Lysosomes

d)

Golgi bodies

21.

Which direction is DNA synthesized in?

a)

3’ → 3’

b)

5’ → 3’

c)

3’ → 1’

d)

5’ → 1’

22.

Which rule describes A pairing with T, and C pairing with G?

a)

Watson’s Rule

b)

Polymerase Rule

c)

Chargaff’s Rule

d)

Franklin’s Rule

23.

What is the central dogma?

a)

Protein → RNA → DNA

b)

RNA → Protein → DNA

c)

DNA → RNA → Protein

d)

DNA → Protein → RNA

24.

Which enzyme builds RNA during transcription?

a)

DNA polymerase

b)

RNA polymerase

c)

Helicase

d)

Ligase

25.

What is a codon?

a)

DNA repair enzyme

b)

Protein subunit

c)

3-base sequence on mRNA

d)

tRNA attachment site

26.

What is an anticodon?

a)

Sequence on DNA

b)

3-base sequence on tRNA

c)

Protein-binding site

d)

Stop signal for DNA polymerase

27.

What does “wobble” refer to?

a)

Misfolding of proteins

b)

Flexibility of the 3rd nucleotide in a codon

c)

Movement of ribosomes

d)

Errors during replication

28.

What is an intron?

a)

Coding region

b)

Non-coding region that is removed

c)

Region of tRNA

d)

Replication enzyme

29.

What is an exon?

a)

Coding region of mRNA

b)

Non-coding region

c)

DNA-binding protein

d)

Polymerase region

30.

What does the 5’ cap do?

a)

Creates mutations

b)

Protects mRNA and helps ribosome binding

c)

Cuts introns

d)

Breaks down RNA

31.

What is a plasmid?

a)

Circular DNA found in bacteria

b)

Part of ribosome

c)

RNA molecule

d)

Mitochondrial enzyme

32.

Transformation is:

a)

Virus transferring DNA

b)

Uptake of DNA from environment

c)

Direct cell-to-cell DNA transfer

d)

Chromosome duplication

33.

What is transduction?

a)

Bacterial conjugation

b)

DNA uptake from the environment

c)

Virus-mediated DNA transfer

d)

tRNA pairing

34.

What is conjugation?

a)

Virus transfers DNA

b)

Direct DNA transfer through a pilus

c)

DNA replication error

d)

Chromosome duplication

35.

What is a silent mutation?

a)

Mutation that doesn’t change amino acid

b)

Mutation creating a stop codon

c)

Mutation shifting reading frame

d)

Mutation causing amino acid change

36.

A missense mutation:

a)

Creates a stop codon

b)

Changes the reading frame

c)

Changes one amino acid

d)

Has no effect

37.

A nonsense mutation:

a)

Changes one amino acid

b)

Creates a premature stop codon

c)

Removes introns incorrectly

d)

Adds extra nucleotides

38.

What do repressors do?

a)

Block transcription

b)

Increase translation

c)

Repair DNA

d)

Speed up RNA polymerase

39.

PCR is used to:

a)

Cut DNA

b)

Amplify DNA

c)

Translate RNA

d)

Sequence amino acids

40.

Restriction enzymes do what?

a)

Copy RNA

b)

Fix mutations

c)

Cut DNA at specific sequences

d)

Build proteins