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WorksheetsIntroduction to Maternal Immunity and Fetal Programming
Total questions: 12
Worksheet time: 6mins
A pregnant patient develops gut dysbiosis. Which outcome is most consistent with the microbiome–immunity slide?
Stronger adaptive responses preventing labour
Enhanced T-reg induction and reduced inflammation
Improved barrier integrity and fewer infections
Higher risk of GDM and pre-eclampsia
A pregnant patient develops gut dysbiosis. Which outcome is most consistent with the microbiome–immunity ?
Stronger adaptive responses preventing labour
Enhanced T-reg induction and reduced inflammation
Improved barrier integrity and fewer infections
Higher risk of GDM and pre-eclampsia
A pregnant patient develops gut dysbiosis. Which outcome is most consistent with the microbiome–immunity ?
Stronger adaptive responses preventing labour
Enhanced T-reg induction and reduced inflammation
Improved barrier integrity and fewer infections
Higher risk of GDM and pre-eclampsia
Why does immune activity become pro-inflammatory again in the third trimester?
To maintain Th2 bias for fetal growth
To initiate labour processes requiring tissue repair
To prevent infections by suppressing neutrophils
To expand T-reg cells for maternal tolerance
How do maternal short-chain fatty acids affect the fetus?
They colonize fetal intestines
They block placental IgG transport
They eliminate maternal microbial antigens
They shape fetal T-cell differentiation
What practice optimizes neonatal microbiome establishment at birth?
Delay skin-to-skin contact
Prefer scheduled cesarean deliveries
Promote vaginal birth when safe
Restrict breastfeeding in early days
Which health domains are most affected by fetal programming?
Only acute infectious disease risk
Long-term physical and mental health
Transient neonatal weight changes
Exclusive musculoskeletal development
Which nursing actions most directly influence maternal–fetal outcomes?
Exclusive reliance on pharmacologic suppression
Education, screening, and microbiome-friendly care
Isolation from community and family support
Universal antibiotics for all pregnancies
Select the best rationale for promoting microbiome-friendly interventions in prenatal care.
They help maintain immune balance for mother and fetus
They eliminate all gastrointestinal symptoms
They increase fetal growth regardless of nutrition
They replace vaccination and screening
A patient asks why immune responses change across trimesters. What is the explanation?
Immunity remains constant
The fetus provides antibodies to the mother
Hormonal shifts eliminate pathogen recognition
Immune modulation supports implantation and growth
Which scenario best illustrates nursing impact aligned with this model?
Avoiding mental health screening
Discouraging vaccinations during pregnancy
Recommending routine fasting
Providing dietary guidance for gut health
Maternal factors can shape offspring health later. Which intervention aligns with this?
Treating only severe acute infections
Focusing on fetal growth ultrasound
Delaying assessments until postpartum
Early identification of stress and nutrition risks
