Worksheetspathology practice quiz
Total questions: 70
Worksheet time: 35mins
A patient has chest pain and biopsy shows loss of nuclei with preserved cell outlines. What type of necrosis is this?
Liquefactive
Coagulative
Caseous
Fat
A liver biopsy shows fatty change from long-term alcohol use. What type of cell injury is this?
Reversible injury
Irreversible injury
Coagulative necrosis
Gangrene
A lymph node biopsy shows shrunken eosinophilic cells with fragmented nuclei (apoptotic bodies). What process is seen?
Necrosis
Apoptosis
Autolysis
Coagulation
Tuberculosis lesion shows cheese-like material. What type of necrosis?
Fat
Caseous
Liquefactive
Fibrinoid
Brain infarction produces soft, liquefied tissue. What necrosis is this?
Liquefactive
Coagulative
Fat
Gangrenous
A patient with chronic hypertension shows increased left ventricular wall thickness. What adaptation is this?
Hyperplasia
Hypertrophy
Atrophy
Metaplasia
A smoker’s bronchi show replacement of columnar epithelium with squamous epithelium. What adaptation?
Dysplasia
Metaplasia
Hyperplasia
Hypertrophy
Cells show increased eosinophilia and membrane rupture after ischemia. What process?
Reversible injury
Apoptosis
Necrosis
Autophagy
Atherosclerotic plaque rupture shows deposits of calcium around dead cells. What is this?
Dystrophic calcification
Metastatic calcification
Hyalinization
Amyloidosis
Hyperparathyroidism leads to calcium deposition in normal tissues. This is:
Dystrophic calcification
Metastatic calcification
Caseous necrosis
Fibrinoid necrosis
Muscle wasting after limb immobilization is:
Atrophy
Hypertrophy
Metaplasia
Hyperplasia
A thyroid gland shows increased cell number due to elevated TSH. This is:
Hypertrophy
Hyperplasia
Metaplasia
Dysplasia
Pancreatitis shows chalky white deposits in fat tissue. Which necrosis?
Fat
Caseous
Coagulative
Liquefactive
Immune-mediated vasculitis shows bright pink necrotic vessel walls. What necrosis?
Caseous
Fibrinoid
Fat
Gangrene
A diabetic foot turns black and dry. What is this?
Wet gangrene
Dry gangrene
Gas gangrene
Liquefactive necrosis
A patient’s colon becomes swollen and dark after bacterial infection in dead tissue. This is:
Dry gangrene
Wet gangrene
Caseous necrosis
Fibrinoid necrosis
Cells show DNA fragmentation but intact membranes. This describes:
Necrosis
Apoptosis
Atrophy
Autophagy
A brain infarct shows cystic space formation. What process explains this?
Coagulative necrosis
Liquefactive necrosis
Atrophy
Calcification
A patient taking chronic steroids shows smaller adrenal cortex. This is:
Hyperplasia
Hypertrophy
Atrophy
Metaplasia
A biopsy shows early reversible injury. Which finding is typical?
Karyolysis
Cell swelling
Eosinophilic cytoplasm
Nuclear fragmentation
A cut shows redness and warmth. These are caused by:
Neutrophils
Vasodilation
Platelet activation
Edema
A pus-filled abscess mainly contains:
Lymphocytes
Macrophages
Neutrophils
Eosinophils
Chronic inflammation of the lung shows clusters of macrophages. What describes this pattern?
Abscess
Granuloma
Fibrosis
Edema
A patient with asthma shows eosinophils in sputum. This is linked to:
Parasites
Viral infection
Allergic inflammation
Fungal infection
Adhesion of leukocytes to endothelium is mediated by:
Histamine
Integrins
Fibrinogen
Collagen
Edema in acute inflammation results from:
Vasoconstriction
Increased vascular permeability
Increased lymphatic flow
Decreased plasma proteins
A biopsy shows multinucleated giant cells. This is typical of:
Acute inflammation
Chronic granulomatous inflammation
Edema
Necrotizing fasciitis
A wound shows fibroblast proliferation and collagen deposition. This is the stage of:
Acute inflammation
Chronic inflammation
Resolution
Tissue remodeling
An allergic reaction releases histamine. Which effect is caused?
Vasoconstriction
Vasodilation + permeability
Fibrosis
Thrombosis
Formation of pus suggests:
Viral infection
Neutrophil-rich inflammation
Macrophage activation
Fibrosis
A wound becomes swollen due to leaking plasma proteins. What mechanism?
Vasoconstriction
Endothelial contraction
Platelet adhesion
Fibrosis
Chronic inflammation shows mainly:
Neutrophils
Lymphocytes and macrophages
Basophils
Platelets
A granuloma forms around TB bacteria. What cell dominates?
Neutrophil
Eosinophil
Macrophage
Mast cell
Chemotaxis primarily involves:
RBCs
WBC movement toward injury
Platelets
Collagen
Fever in inflammation happens due to:
IL-1 and TNF
IgE
Complement
Histamine
Chronic inflammation causes tissue destruction due to:
Platelets
Neutrophils
Macrophage enzymes
Complement C5a
A patient has a viral infection. Which WBC is increased?
Neutrophils
Lymphocytes
Basophils
Eosinophils
A wound shows blood vessel sprouting. This process is:
Scar maturation
Angiogenesis
Leukocytosis
Necrosis
Hypertension damages endothelial cells leading to chronic inflammation. Which molecule increases adhesion?
Heparin
Selectins
Albumin
Collagen
A patient with rheumatoid arthritis shows thick inflamed synovium. This is:
Acute inflammation
Chronic autoimmune inflammation
Necrosis
Edema
A patient with right-sided heart failure develops leg swelling. What causes this edema?
Increased plasma proteins
Increased hydrostatic pressure
Lymphatic blockage
Sodium loss
A nephrotic syndrome patient shows low albumin and body swelling. Select right mechanism?
High hydrostatic pressure
Low oncotic pressure
Lymphatic obstruction
Inflammation
A woman has pinpoint red skin spots after platelet count drops. Select right diagnosis?
Hematoma
Ecchymosis
Purpura
Petechiae
Trauma leads to a large blue-purple skin patch. This is:
Petechiae
Purpura
Ecchymosis
Thrombus
A patient has liver cirrhosis with abdominal fluid. Mechanism?
Increased oncotic pressure
Increased hydrostatic pressure in portal vein
Decreased sodium
Increased lymphatic drainage
A deep vein thrombosis forms due to stasis. This relates to:
Virchow's triad
Complement activation
Gangrene
Apoptosis
A septic patient develops warm skin and low blood pressure. Which shock?
Cardiogenic
Hypovolemic
Septic
Neurogenic
A patient with massive blood loss becomes pale with rapid pulse. What shock?
Septic
Hypovolemic
Cardiogenic
Neurogenic
A heart attack causes pump failure and hypotension. Which shock?
Septic
Cardiogenic
Hypovolemic
Hemolytic
A patient on warfarin develops spontaneous bruises. Reason?
Platelet dysfunction
Clotting factor deficiency
Vessel rupture
Leukopenia
A man with DIC shows widespread microthrombi. What is the major danger?
Hypertension
Organ failure
Platelet overproduction
Increased RBC count
A woman develops swelling due to lymphatic obstruction from tumor. This edema results from:
High hydrostatic pressure
Low oncotic pressure
Lymphatic blockage
Sodium depletion
A patient in shock has cold, clammy skin. This suggests:
Septic shock
Hypovolemic shock
Allergic shock
Neurogenic shock
A child has bleeding under the skin in patches 3–10 mm. This is:
Petechiae
Purpura
Hematoma
Ecchymosis
A lung shows blood-filled alveoli after heart failure. What is this?
Edema
Hemorrhage
Infarction
Atrophy
Atherosclerosis leads to vessel narrowing and tissue ischemia. What complication may follow?
Fat necrosis
Coagulative necrosis
Caseous necrosis
Hydropic change
A patient with hypertension develops microaneurysms in vessels. What type of hemorrhage may occur?
Petechiae
Purpura
Ecchymosis
Hematoma
A cancer patient develops thrombosis due to tissue factor release. Mechanism?
Platelet deficiency
Hypercoagulability
Vasodilation
High fibrinolysis
A patient with anaphylaxis becomes hypotensive. What shock?
Septic
Cardiogenic
Hypovolemic
Anaphylactic
A patient’s leg shows pitting edema. What substance accumulates?
Blood
Protein-poor fluid
Pus
Calcium
Chronic liver disease reduces albumin production. This causes:
Increased oncotic pressure
Decreased oncotic pressure
Increased hydrostatic pressure
Lymphatic obstruction
A person with long flight immobility develops DVT. What part of Virchow’s triad?
Hypercoagulability
Endothelial injury
Stasis
Vessel compression
A patient with bacterial meningitis develops petechiae. Cause?
Low WBC
Platelet consumption in DIC
Increased RBC
Dehydration
A child with vitamin C deficiency has gum bleeding. Mechanism?
Platelet disorder
Vessel wall fragility
Clotting factor deficiency
High fibrin
A patient with pulmonary embolism shows sudden dyspnea. Source is usually:
Arterial thrombus
Leg DVT
Heart valve
Aneurysm
A man has a red, swollen limb after venous thrombosis. What causes the redness?
Arterial block
Increased hydrostatic pressure
Tissue necrosis
Dehydration
A teenage girl with nosebleeds and heavy menses has normal platelets but prolonged PTT. This suggests:
Platelet defect
Coagulation factor defect
Vessel fragility
Polycythemia
An elderly patient collapses with low blood pressure after myocardial infarction. Likely outcome of shock?
Complete recovery
Multi-organ failure
Hypercoagulation
Pitting edema
A man has pink frothy sputum after left-sided heart failure. This is:
Pulmonary edema
Hematoma
Hemothorax
Purpura
A patient with splenomegaly has low platelets and widespread small bleeding spots. This is:
Petechiae
Ecchymosis
Purpura
Hematoma
