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Acute Inflammation Quiz

Total questions: 21

Worksheet time: 11mins

Name
Class
Date
1.

Inflammation is best defined as

a)

A local response of living vascularized tissue to injury

b)

An immune response only against infections

c)

A reversible tissue injury

d)

Healing by fibrosis only

2.

Which of the following is NOT a cardinal sign of acute inflammation?

a)

Redness

b)

Swelling

c)

Pain

d)

Atrophy

3.

The cardinal signs of inflammation were first described by

a)

Celsus

b)

Virchow

c)

Galen

d)

Hippocrates

4.

Heat in acute inflammation is primarily due to

a)

Vasodilatation

b)

Increased vascular permeability

c)

Leukocyte migration

d)

Nerve stimulation

5.

The earliest vascular change in acute inflammation is

a)

Transient vasoconstriction

b)

Arteriolar vasodilatation

c)

Venous thrombosis

d)

Endothelial injury

6.

Increased vascular permeability in acute inflammation is mainly due to

a)

Endothelial contraction

b)

Endothelial necrosis

c)

Leukocyte emigration

d)

Platelet aggregation

7.

Which mediator causes immediate transient increase in vascular permeability?

a)

Histamine

b)

Prostaglandins

c)

Leukotriene B4

d)

Interferon gamma

8.

Margination of leukocytes occurs due to

a)

Slowing of blood flow

b)

Vasodilatation

c)

Increased permeability

d)

Endothelial proliferation

9.

The principal leukocyte in acute inflammation is

a)

Eosinophil

b)

Neutrophil

c)

Lymphocyte

d)

Macrophage

10.

Diapedesis refers to

a)

Rolling of leukocytes

b)

Adhesion to endothelium

c)

Migration through endothelium

d)

Chemotaxis

11.

Which adhesion molecule is expressed on leukocytes during firm adhesion?

a)

Selectins

b)

Integrins

c)

Cadherins

d)

PECAM-1

12.

PECAM-1 (CD31) plays a major role in

a)

Rolling

b)

Adhesion

c)

Diapedesis

d)

Chemotaxis

13.

Chemotaxis of leukocytes is mediated by

a)

IL-2

b)

C5a

c)

Histamine

d)

Serotonin

14.

The process of ingestion of microbes by neutrophils is called

a)

Diapedesis

b)

Opsonization

c)

Phagocytosis

d)

Chemotaxis

15.

Which of the following is an opsonin?

a)

IgG

b)

C3b

c)

CRP

d)

All of the above

16.

Respiratory burst in neutrophils results in formation of

a)

Hydrogen peroxide

b)

Nitric oxide

c)

Superoxide anion

d)

All of the above

17.

Which enzyme is responsible for conversion of H2O2 to hypochlorous acid?

a)

Catalase

b)

Myeloperoxidase

c)

Superoxide dismutase

d)

NADPH oxidase

18.

Which of the following is an outcome of acute inflammation?

a)

Resolution

b)

Suppuration

c)

Chronic inflammation

d)

All of the above

19.

Fibrinous inflammation is most commonly seen in

a)

Serous cavities

b)

Skin epidermis

c)

Brain parenchyma

d)

Renal tubules

20.

Suppurative inflammation is characterized by

a)

Protein-rich fluid

b)

Granuloma formation

c)

Pus formation

d)

Minimal tissue injury

21.

The most common morphological pattern of acute inflammation in burns is

a)

Serous

b)

Fibrinous

c)

Suppurative

d)

Ulcerative