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lecture 27 (371)

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

What is the role of an enhancer in transcription initiation?

a)

It is located within the gene.

b)

It binds to the silencer sequence.

c)

It regulates initiation of transcription by turning genes ON.

d)

It prevents transcription from occurring.

2.

What does a repressor do in the context of transcription?

a)

It turns genes ON.

b)

It enhances the binding of RNA polymerase.

c)

It binds to the promoter region.

d)

It prevents the RNA polymerase from starting transcription.

3.

Where can enhancer sequences be found?

a)

Only downstream of the promoter.

b)

Only upstream of the promoter.

c)

Upstream or downstream of the promoter region.

d)

Only within the gene.

4.

What is the function of a silencer?

a)

To enhance transcription.

b)

To facilitate RNA polymerase binding.

c)

To bind to the promoter region.

d)

To turn genes OFF.

5.

What happens when an activator binds to an enhancer?

a)

It degrades the RNA polymerase.

b)

It prevents DNA looping.

c)

It blocks the transcription initiation complex.

d)

It facilitates contact with the initiation complex.

6.

What is a key difference between prokaryotic and eukaryotic repressors?

a)

Prokaryotic repressors bind to enhancers.

b)

Eukaryotic repressors are always located within the gene.

c)

Eukaryotic repressors bind to operators.

d)

Prokaryotic repressors bind to operators within operons.

7.

What is the binding site of activators?

a)

Silencer.

b)

Promoter.

c)

Operator.

d)

Enhancer.

8.

What occurs during competitive DNA binding?

a)

Activators and repressors compete for binding.

b)

Repressors and activators work together.

c)

Only activators bind to DNA.

d)

Only repressors bind to DNA.

9.

What do co-activators and co-repressors lack?

a)

Transcription initiation complex.

b)

DNA binding domains.

c)

Regulatory genes.

d)

Protein binding domains.

10.

How do eukaryotic repressors interact with the transcription initiation complex?

a)

By enhancing RNA polymerase activity.

b)

By binding to the silencer and interacting with the complex.

c)

By blocking the binding of activators.

d)

By promoting DNA looping.

11.

What is the primary function of transcription initiation complex?

a)

To initiate transcription.

b)

To degrade RNA.

c)

To enhance gene expression.

d)

To bind to silencer sequences.

12.

What is the role of DNA loops in transcription regulation?

a)

They bring distant regulatory elements into contact.

b)

They degrade the transcription initiation complex.

c)

They enhance the silencer's function.

d)

They prevent the binding of RNA polymerase.

13.

What happens if a repressor binds first in competitive DNA binding?

a)

The gene is ON.

b)

RNA polymerase is activated.

c)

Transcription is enhanced.

d)

The gene is OFF.

14.

What type of protein is an activator?

a)

A protein that inhibits transcription.

b)

A regulatory protein with two binding domains.

c)

A regulatory protein with one binding domain.

d)

A protein that binds to silencer sequences.

15.

What is the primary function of co-activators?

a)

To degrade RNA.

b)

To bind to DNA directly.

c)

To provide an additional layer of regulation.

d)

To inhibit transcription.