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Neurocutaneous disorders Quiz

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

Which gene is mutated in Neurofibromatosis type 1?

a)

TSC1

b)

GNAQ

c)

NF1

d)

PTEN

2.

Which of the following is NOT a feature of NF1?

a)
  • Lisch nodules

b)
  • Café-au-lait spots

c)
  • Neurofibromas

d)
  • Port-wine stain

3.
  • Which is the most common neurological manifestation of TSC?

a)

seizures

b)

Stroke

c)

Migraine

d)
  • Dementia

4.
  • Which organ is most commonly affected by angiomyolipomas in TSC?

a)

liver

b)

Brain

c)

kidney

d)

lung

5.
  • Ash-leaf spots are characteristic of which condition?

a)
  • NF1

b)

SWS

c)

TSC

d)
  • Neuroblastoma

6.
  • Glaucoma is a common complication in which disorder?

a)
  • NF1

b)

TSC

c)

Sturge- Weber syndrome

d)
  • Ataxia telangiectasia

7.
  • Which skin lesion is most characteristic of Sturge–Weber syndrome?

a)

Shagreen patch

b)

Café-au-lait spot

c)

Hypomelanotic macule

d)

Port-wine stain

8.

Which syndrome is associated with learning disabilities and ADHD?

a)

SWS only

b)

TSC only

c)

NF1 only

d)

NF1 and TSC

9.

Sturge–Weber syndrome is a hereditary disorder

a)

True ✅

b)

False ❌

10.
  • Café-au-lait spots are a common feature of NF1

a)

True ✅

b)

False ❌

11.

NF1 patients have an increased risk of tumor formation

a)

True ✅

b)

False ❌

12.

Port-wine stains in SWS usually follow the trigeminal nerve distribution.

a)

True ✅

b)

False ❌

13.

TSC-associated seizures can often begin in infancy.

a)

True ✅

b)

False ❌

14.

NF1 is caused by mutations in the TSC1 or TSC2 genes.

a)

True ✅

b)

False ❌

15.

Seizures are a rare feature of SWS.

a)

True ✅

b)

False ❌