WorksheetsNeurocutaneous disorders Quiz
Total questions: 15
Worksheet time: 8mins
Which gene is mutated in Neurofibromatosis type 1?
TSC1
GNAQ
NF1
PTEN
Which of the following is NOT a feature of NF1?
Lisch nodules
Café-au-lait spots
Neurofibromas
Port-wine stain
Which is the most common neurological manifestation of TSC?
seizures
Stroke
Migraine
Dementia
Which organ is most commonly affected by angiomyolipomas in TSC?
liver
Brain
kidney
lung
Ash-leaf spots are characteristic of which condition?
NF1
SWS
TSC
Neuroblastoma
Glaucoma is a common complication in which disorder?
NF1
TSC
Sturge- Weber syndrome
Ataxia telangiectasia
Which skin lesion is most characteristic of Sturge–Weber syndrome?
Shagreen patch
Café-au-lait spot
Hypomelanotic macule
Port-wine stain
Which syndrome is associated with learning disabilities and ADHD?
SWS only
TSC only
NF1 only
NF1 and TSC
Sturge–Weber syndrome is a hereditary disorder
True ✅
False ❌
Café-au-lait spots are a common feature of NF1
True ✅
False ❌
NF1 patients have an increased risk of tumor formation
True ✅
False ❌
Port-wine stains in SWS usually follow the trigeminal nerve distribution.
True ✅
False ❌
TSC-associated seizures can often begin in infancy.
True ✅
False ❌
NF1 is caused by mutations in the TSC1 or TSC2 genes.
True ✅
False ❌
Seizures are a rare feature of SWS.
True ✅
False ❌
