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Pharmacology of Asthma and Diabetes

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

Which of the following best describes the primary mechanism of action of metformin.

a)

Increases insulin secretion from pancreatic beta cells

b)

Decreases hepatic glucose production and improves insulin sensitivity.

c)

Delays intestinal absorption of glucose.

d)

Activates insulin receptors to increase glucose uptake.

2.

Which of the following is the most common side effect associated with metformin?

a)

Hypoglycemia

b)

Weight gain

c)

Gastrointestinal upset

d)

Peripheral edema

3.

Which medication is considered first-line for the prevention of exercise-induced bronchoconstriction, and when should it be administered?

a)

Montelukast, taken daily at bedtime

b)

Inhaled corticosteroid, taken immediately before exercise

c)

Albuterol, 5-15 minutes prior to exercise

d)

Ipratropium, taken after onset of symptoms

4.

Fluticasone/Salmeterol is commonly known as ____?

a)

Montelukast

b)

Albuterol

c)

Advair

d)

Combivent

5.

A 6-year-old child is being treated for a suspected bacterial infection. The provider considers prescribing tetracycline. Which of the following is the primary reason tetracycline is contraindicated in young children?

a)

It causes irreversible hepatotoxicity

b)

It interferes with normal bone and tooth development

c)

It leads to severe hypoglycemia in pediatric patients

d)

It increases the risk of ototoxicity and hearing loss

6.

A 55-year-old patient with cirrhosis (Child-Pugh class C) is prescribed ondansetron for chemotherapy-induced nausea. What should the provider be aware of regarding dosing?

a)

No adjustment is necessary, use standard dosing to best prevent nausea

b)

Decrease the dose by 50% and maintain usual frequency

c)

Limit the total daily dose to 8 mg

d)

Increase the dosing interval to every 12 hours only

7.

A 68-year-old patient with Parkinson disease is started on amantadine to help reduce tremor and rigidity. Which patient education point is most important for the provider to include?

a)

Stop the medicine immediately if experience dizziness

b)

This medication may cause livedo reticularis and edema

c)

Take this medication only at bedtime

d)

Avoid foods high in tyramine while taking this medicine

8.

A patient with heart failure is prescribed furosemide. Which adverse effect should the provider monitor most closely?

a)

Hyperkalemia and gynecomastia

b)

Hypercalcemia and constipation

c)

Hypokalemia and ototoxicity

d)

Metabolic acidosis and paresthesias

9.

A patient taking hydrochlorothiazide for hypertension should be monitored for which common metabolic effect?

a)

Hyperuricemia and hyperglycemia

b)

Hypocalcemia and anemia

c)

Hyperkalemia and metabolic alkalosis

d)

Bradycardia and hypotension

10.

A 22-year-old patient is prescribed the etonogestrel/ethinyl estradiol vaginal ring (NuvaRing) for contraception. Which of the following is the most common side effect she should be counseled about?

a)

Liver failure

b)

Vaginal irritation or discharge

c)

Permanent infertility

d)

Osteoporosis

11.

A patient taking a CYP1A2 substrate (e.g., theophylline) quits smoking abruptly. Which of the following is most likely?

a)

Drug metabolism slows, leading to higher plasma drug concentrations

b)

Drug metabolism accelerates, leading to subtherapeutic levels

c)

Smoking cessation has no effect on CYP1A2 substrate levels

d)

CYP1A2 inhibition causes decreased drug absorption

12.

A 34-year-old patient with newly diagnosed hyperthyroidism is started on Tapazole. What is the primary mechanism by which this medication reduces thyroid hormone levels?

a)

Inhibits the release of preformed thyroid hormone from the thyroid gland

b)

Blocks the conversion of T4 to T3 in peripheral tissues

c)

Inhibits thyroid peroxidase, preventing synthesis of T3 and T4

d)

Stimulates the pituitary to decrease TSH production

13.

A 55-year-old patient with chronic insomnia is prescribed ramelteon. Which of the following best describes the mechanism of action of this medication?

a)

Potentiates GABA-A receptor activity to induce sedation

b)

Inhibits reuptake of serotonin and norepinephrine to promote sleep

c)

Melatonin receptor agonist that regulates the sleep-wake cycle

d)

Blocks histamine H1 receptors to induce drowsiness

14.

Which of the following is the most common adverse effect associated with ramelteon?

a)

Dependence and tolerance

b)

Next-day sedation

c)

Dizziness and somnolence

d)

Weight gain

15.

A 25-year-old patient presents with mild community-acquired pneumonia. Laboratory testing confirms Mycoplasma pneumoniae infection. Which of the following antibiotics would not be effective against this organism?

a)

Azithromycin

b)

Doxycycline

c)

Levofloxacin

d)

Amoxicillin