wayground logo

Free Printable Worksheets

NEW

Font size

S
M
L
XL
Worksheets

Antiepileptic Drugs Quiz

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

Antiepileptic drugs act mainly by

a)

Enhancing excitatory transmission

b)

Reducing neuronal excitability

c)

Increasing glutamate release

d)

Blocking GABA synthesis

2.

Phenytoin primarily acts by

a)

Blocking T-type Ca channels

b)

Blocking voltage-gated Na+ channels

c)

Enhancing GABA action

d)

Inhibiting NMDA receptors

3.

Sodium valproate has which major mechanism?

a)

Only Na+ channel blockade

b)

Only GABA inhibition

c)

Na+ channel blockade and ↑ GABA levels

d)

T-type Ca channel blockade only

4.

Drug of choice for absence seizures is

a)

Phenytoin

b)

Carbamazepine

c)

Ethosuximide

d)

Sodium valproate

5.

Ethosuximide acts mainly by blocking

a)

T-type Ca channels

b)

Na+ channels

c)

GABA-A receptors

d)

NMDA receptors

6.

Broad-spectrum antiepileptic drug is

a)

Phenytoin

b)

Carbamazepine

c)

Phenobarbitone

d)

Sodium valproate

7.

Phenytoin follows which kinetics at therapeutic range?

a)

Zero-order only

b)

First-order only

c)

Mixed first to zero order

d)

Nonlinear only

8.

Common adverse effect of phenytoin is

a)

Gingival hyperplasia

b)

Parkinsonism

c)

Hepatotoxicity only

d)

Nephrotoxicity

9.

Teratogenic effect classically associated with phenytoin is

a)

Neural tube defect

b)

Fetal hydantoin syndrome

c)

Phocomelia

d)

Cleft palate

10.

Sodium valproate is contraindicated in

a)

Epilepsy

b)

Bipolar disorder

c)

Pregnancy

d)

Absence seizures

11.

Major adverse effect of sodium valproate includes

a)

Hypoglycemia

b)

Weight gain and hepatotoxicity

c)

Gingival hyperplasia

d)

Osteoporosis

12.

Phenobarbitone primarily enhances

a)

Na+ channel inactivation

b)

GABA-mediated Cl− influx

c)

Ca2+ channel blockade

d)

Glutamate release

13.

Phenobarbitone differs from benzodiazepines by

a)

Increasing frequency of Cl− channel opening

b)

Increasing duration of Cl− channel opening

c)

Acting only on GABA-B receptors

d)

Having no sedative action

14.

Therapeutic use of phenobarbitone includes

a)

Absence seizures

b)

Generalized tonic–clonic seizures

c)

Myoclonic seizures only

d)

Panic disorder

15.

Adverse effect of phenobarbitone includes

a)

Insomnia

b)

Hyperactivity in children

c)

Respiratory depression at high dose

d)

Hepatotoxicity only

16.

Phenobarbitone induces hepatic enzymes leading to

a)

Increased drug levels

b)

Reduced metabolism of drugs

c)

Drug interactions

d)

Reduced clearance

17.

Phenytoin is ineffective in

a)

Generalized tonic–clonic seizures

b)

Partial seizures

c)

Status epilepticus (IV)

d)

Absence seizures

18.

Drug of choice for status epilepticus (acute control) is

a)

Phenytoin oral

b)

Diazepam IV

c)

Carbamazepine

d)

Ethosuximide

19.

Valproate is useful in which seizure type?

a)

Absence only

b)

Myoclonic seizures

c)

Partial seizures only

d)

Febrile seizures only

20.

Mechanism contributing to valproate efficacy in absence seizures is

a)

Na+ channel blockade only

b)

Enhanced GABA only

c)

T-type Ca channel blockade

d)

None

Similar Resources on Wayground

Principles of Marketing Quiz

15 questions

Principles of Marketing Quiz

quiz

Worksheet

•

University

Peran Komunikasi Interpersonal Dalam Praktik Keperawatan

16 questions

Peran Komunikasi Interpersonal Dalam Praktik Keperawatan

quiz

Worksheet

•

University

Soalan Komunikasi

15 questions

Soalan Komunikasi

quiz

Worksheet

•

University