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Solution Preparation Calculations Worksheet

Total questions: 18

Worksheet time: 28mins

Name
Class
Date
1.

How much Tween 20 is needed to prepare 250 mL of 10% Tween 20 (v/v)?

Answer to one decimal place.

a)

20.0 mL

b)

25.0 mL

c)

50.0 mL

d)

75.0 mL

2.

How much Tween 20 is needed to prepare 250 mL of 25% Tween 20 (v/v)?

Answer to one decimal place.

a)

50.0 mL

b)

62.5 mL

c)

75.0 mL

d)

100.0 mL

3.

How much NaCl is needed to prepare 400 mL of 5% NaCl (w/v)?

Answer to one decimal place.

a)

10.0 g

b)

15.0 g

c)

20.0g

d)

25.0g

4.

How much SDS is needed to prepare 350 mL of 10% SDS (w/v)?Answer to one decimal place.

a)

30.0 g

b)

35.0 g

c)

40.0 g

d)

45.0 g

5.

How much BSA is needed to prepare 50 mL of 5 mg/mL of BSA?

Answer to zero decimal places.

a)

125 mg

b)

200 mg

c)

250 mg

d)

500 mg

6.

How much tetracycline is needed to prepare 100 mL of 100 mg/mL tetracycline?

Answer to one decimal place.

a)

1.0 g

b)

5.0 g

c)

10.0 g

d)

12.0g

7.

How much Ca(NO3)2 is needed to prepare 500 mL of 0.5 M Ca(NO3)2? MW = 164.09 g/mol

Answer to two decimal places

a)

20.51 g

b)

41.02 g

c)

82.05 g

d)

102.57 g

8.

How much NaCl is needed to prepare 250 mL of 0.5 M NaCl? MW of NaCl = 58.44 g/mol

Answer to three decimal places

a)

5.844 g

b)

7.305 g

c)

8.766 g

d)

11.688 g

9.

How much CaCl2 is needed to prepare 100 mL of 50 mM CaCl2? MW of CaCl2 = 110.98 g/mol

Answer to 3 decimal places

a)

0.111 g

b)

0.278 g

c)

0.555 g

d)

1.110 g

10.

Using the dilution formula C1V1=C2V2C_1V_1=C_2V_2 , determine the volumes of stock solution and water needed to prepare 100 mL of 2.5 X NaOH solution from 50 X NaOH solution. Choose the correct pair: Stock volume; Water volume.

a)

Stock: 5 mL; Water: 95 mL

b)

Stock: 2.5 mL; Water: 97.5 mL

c)

Stock: 10 mL; Water: 90 mL

d)

Stock: 20 mL; Water: 80 mL

11.

If I have 340 mL of a 0.5 M NaBr solution, what will the concentration be if I add 560 mL more water to it?

a)

.188 M

b)

3.78 M

c)

.389 M

d)

1.76 M

12.
Find the molarity of 186.55 g of sucrose, C12H22O11 (MM = 342) in 250 mL of water.
a)
2.18 M
b)
0.746 M
c)
1.18 M
d)
0.545 M
13.

In the equation, A = ebc, what quantity is represented by "e" ?

a)

Molar Absorbtivity

b)

Path Length

c)

Concentration

d)

Absorbance

14.

Which of the following best describes Lambert-Beer’s Law in spectrophotometry?

a)

The absorbance of a solution is directly proportional to the concentration of the absorbing species and the path length of the sample.

b)

The transmittance of a solution increases as the concentration of the absorbing species increases.

c)

The intensity of transmitted light is independent of the sample concentration and path length.

d)

The absorbance of a solution remains constant regardless of changes in concentration or path length.

15.

What is the technique used to separate molecules on the basis of size or density by high speed spinning?

a)

Homogenization

b)

Centrifugation

c)

Filtration

d)

Chromatography

16.

What is the main purpose of filtration in protein purification?

a)

To remove cellular debris

b)

To concentrate the cells

c)

To separate the protein from other molecules

d)

To break the cells open

17.

What is the main purpose of size exclusion chromatography?

a)

To separate molecules based on size/shape

b)

To separate molecules based on charge

c)

To separate molecules based on hydrophobicity

d)

To separate molecules based on affinity

18.

What is the purpose of the wash buffer (WB) applied to the column after the supernatant?

a)

The wash buffer is used to remove the green fluorescent protein from the column so that it can be collected.

b)

The wash buffer is used to remove hydrophilic cellular proteins that are not bound to the beads.

c)

The wash buffer is used to remove the hydrophobic cellular proteins that are bound to the beads.