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Fluid cytology

Total questions: 23

Worksheet time: 12mins

Name
Class
Date
1.

Body cavities are lined by which type of cells?

a)

Squamous epithelial cells

b)

Cuboidal epithelial cells

c)

Mesothelial cells

d)

Endothelial cells

2.

Which of the following is NOT a serous cavity?

a)

Pleural cavity

b)

Pericardial cavity

c)

Peritoneal cavity

d)

Synovial cavity

3.

Serous membranes are normally lined by:

a)

Stratified squamous epithelium

b)

Pseudostratified epithelium

c)

Single layer of mesothelial cells

d)

Transitional epithelium

4.

Excess accumulation of serous fluid in a body cavity is termed:

a)

Transudate

b)

Exudate

c)

Effusion

d)

Ascites

5.

The normal volume of serous fluid in the peritoneal cavity is approximately:

a)

5 mL

b)

20 mL

c)

50 mL

d)

100 mL

6.

An effusion is always caused by:

a)

Physiological processes

b)

Aging

c)

Pathological processes

d)

Trauma alone

7.

Effusions are classified into how many major categories?

a)

Two

b)

Three

c)

Four

d)

Five

8.

Which of the following is NOT a category of effusion?

a)

Hydrostatic

b)

Infectious

c)

Malignant

d)

Degenerative

9.

Each category of effusion can be classified into:

a)

Acute or chronic

b)

Benign or malignant

c)

Transudate or exudate

d)

Septic or aseptic

10.

Which stain is commonly used in fluid cytology?

a)

Ziehl–Neelsen stain

b)

PAS stain

c)

Papanicolaou stain

d)

Reticulin stain

11.

Which method allows histopathological examination of fluid sediment?

a)

Cytospin

b)

Cell block

c)

Wet mount

d)

Frozen section

12.

Principal benign cells seen in effusions include all EXCEPT:

a)

Mesothelial cells

b)

Macrophages

c)

Blood cells

d)

Plasma cells

13.

Mesothelial cells are approximately what size?

a)

5–10 µm

b)

10–15 µm

c)

15–20 µm

d)

25–30 µm

14.

The “windows” seen between mesothelial cells are due to:

a)

Cell degeneration

b)

Microvilli separating the cells

c)

Nuclear shrinkage

d)

Cytoplasmic vacuoles

15.

The nuclei of mesothelial cells typically show:

a)

Coarse chromatin with absent nucleoli

b)

Dense hyperchromasia

c)

Delicate chromatin with prominent nucleoli

d)

Smudged chromatin

16.

Reactive mesothelial cells commonly show:

a)

Nuclear molding

b)

Binucleation and multinucleation

c)

High mitotic activity

d)

Keratin pearl formation

17.

Effusions in congestive heart failure commonly contain:

a)

Numerous eosinophils

b)

Sheets of malignant cells

c)

Polymorphonuclear leukocytes and mesothelial cells

d)

Granulomas

18.

Chronic pleural effusion due to pulmonary infarcts shows:

a)

Absence of mesothelial cells

b)

Proliferation of mesothelial cells in sheets

c)

Predominant lymphocytes

d)

Signet ring cells

19.

Eosinophilic pleural effusion is defined by eosinophils comprising:

a)

More than 5%

b)

More than 8%

c)

More than 10%

d)

More than 20%

20.

Long-standing ascites in cirrhosis shows mesothelial cells with:

a)

Large prominent nucleoli

b)

Papillary or rosette-like clusters

c)

Marked pleomorphism

d)

High mitotic activity

21.

The most common metastatic tumor seen in effusions is:

a)

Squamous cell carcinoma

b)

Small cell carcinoma

c)

Adenocarcinoma

d)

Sarcoma

22.

Which of the following is a positive mesothelial marker?

a)

Ber-EP4

b)

MOC-31

c)

Calretinin

d)

CDX-2

23.

Which of the following is a negative mesothelial marker?

a)

WT-1

b)

CK 5/6

c)

D2-40

d)

Ber-EP4