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Opioid Analgesics Quiz

Total questions: 19

Worksheet time: 10mins

Name
Class
Date
1.

Opioid analgesics primarily act on

a)

Histamine receptors

b)

GABA receptors

c)

Opioid receptors

d)

Dopamine receptors

2.

Morphine is classified as

a)

NSAID

b)

Pure opioid agonist

c)

Partial agonist antagonist

d)

Opioid antagonist

3.

Most important receptor mediating analgesia of morphine is

a)

κ receptor

b)

δ receptor

c)

μ receptor

d)

NMDA receptor

4.

Morphine produces analgesia by

a)

Blocking COX enzymes

b)

Increasing pain threshold and altering pain perception

c)

Blocking sodium channels

d)

Stimulating NMDA receptors

5.

Morphine causes respiratory depression by acting on

a)

Peripheral chemoreceptors

b)

Medullary respiratory center

c)

Cortex only

d)

Bronchial smooth muscle

6.

Morphine causes miosis by stimulation of

a)

Sympathetic fibers

b)

Parasympathetic Edinger–Westphal nucleus

c)

Nicotinic receptors

d)

Dopamine receptors

7.

Morphine causes constipation due to

a)

Increased GI motility

b)

Decreased GI motility and increased sphincter tone

c)

Increased bile flow

d)

Pancreatic stimulation

8.

Common adverse effect of morphine includes

a)

Diarrhea

b)

Hypertension

c)

Nausea and vomiting

d)

Hyperglycemia

9.

Morphine can cause hypotension mainly due to

a)

Direct vasoconstriction

b)

Histamine release

c)

Increased cardiac output

d)

Beta stimulation

10.

Morphine is used in myocardial infarction because it

a)

Increases heart rate

b)

Increases myocardial oxygen demand

c)

Relieves pain and reduces anxiety with venodilation

d)

Acts as antiarrhythmic

11.

Triad of opioid poisoning includes

a)

Mydriasis tachycardia fever

b)

Coma miosis respiratory depression

c)

Seizures hypertension hyperthermia

d)

Diarrhea salivation lacrimation

12.

Drug of choice for morphine poisoning is

a)

Atropine

b)

Naloxone

c)

Flumazenil

d)

Physostigmine

13.

Naloxone is a

a)

Partial agonist

b)

μ receptor agonist

c)

Opioid antagonist

d)

NSAID

14.

Management of opioid poisoning includes all EXCEPT

a)

Airway support

b)

Naloxone administration

c)

Gastric lavage if appropriate

d)

IV beta blockers

15.

Thiopentone sodium is classified as

a)

Benzodiazepine

b)

Barbiturate used for induction agent

c)

Opioid analgesic

d)

NMDA antagonist

16.

Thiopentone produces anesthesia by

a)

Enhancing GABA-A action

b)

Blocking NMDA receptors

c)

Blocking Na+ channels

d)

Inhibiting dopamine release

17.

Thiopentone is contraindicated in

a)

Status epilepticus

b)

Porphyria

c)

Short procedures

d)

Induction of anesthesia

18.

Major adverse effect of thiopentone is

a)

Bronchodilation

b)

Respiratory depression and hypotension

c)

Analgesia

d)

Hypertension

19.

Ultra-short acting barbiturate is

a)

Phenobarbitone

b)

Pentobarbitone

c)

Thiopentone

d)

Methadone