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Worksheetspost test 3.4 mikrobiologi
Total questions: 10
Worksheet time: 5mins
A medical student is asked about the shape of Leptospira interrogans. Which description is correct?
Round cocci
Straight rod
Thin spiral-shaped bacterium
Square-shaped bacterium
Club-shaped bacterium
Which laboratory method allows direct visualization of Leptospira in clinical specimens?
Gram staining
Acid-fast staining
Dark-field microscopy
ELISA
MAT
A patient presents on day 3 of fever with suspected leptospirosis. Which laboratory examination is most appropriate at this stage?
Microscopic Agglutination Test (MAT)
IgM ELISA
Rapid antibody test
PCR on blood specimen
Urine culture
A medical student is asked to collect the most appropriate specimen during the leptospiremic phase of leptospirosis. Which specimen should be collected?
Urine
Stool
Blood
A patient in the second week of illness shows a rising antibody titer on the Microscopic Agglutination Test (MAT). This finding indicates which disease phase?
Incubation phase
Leptospiremic phase
Prodromal phase
Immune phase
Convalescent phase
Which laboratory test is most likely to yield a positive result during the immune phase of leptospirosis?
Dark-field microscopy of blood
Blood culture
PCR on blood
Microscopic Agglutination Test (MAT)
Gram staining
A positive IgM ELISA result in leptospirosis is most likely detected in which period?
First day of fever
Second day of fever
Early leptospiremic phase
Late first week to second week of illness
Before symptom onset
Which pairing of specimen type and timing of collection is the most appropriate in leptospirosis?
Blood – second week of illness
Urine – early febrile phase
Cerebrospinal fluid – incubation phase
Urine – immune phase
Tissue – pre-symptomatic phase
A patient suspected of leptospirosis has a negative PCR result on blood but a positive MAT with high antibody titer. What is the most appropriate interpretation?
The patient is still in the leptospiremic phase
No infection has occurred
The patient is in the immune phase
PCR was performed incorrectly
Leptospira are present only in urine
Which of the following is the most appropriate laboratory safety principle when handling suspected leptospirosis specimens?
Specimens can be handled without PPE because the disease is not airborne
All specimens are considered non-infectious
Use gloves and eye protection when handling specimens
Urine specimens do not require special precautions
Dark-field microscopy poses no biosafety risk
