Font size
WorksheetsCancer Biology- Test 1 PQs
Total questions: 35
Worksheet time: 24mins
Which of the following is NOT one of the most commonly diagnosed cancers?
liver
lung
colorectal
kidney
Which of the following cancers occurs in kids (aged 0-14)?
erythrocytic
rhabdomyoma
thyroid cancer
leukemia
Which of the following cancers are increasing in men?
lung cancer
pancreatic
testicular
leukemia
Hodgekin Lymphoma
Which cancer is most commonly diagnosed in those aged 15-29?
(a)
Which of the following cancers are increasing in women?
myeloma, myoma, endometrial
myeloma, melanoma, myoma
endometrial, melanoma, uterine
melanoma, myeloma, uterine
The function of which normal cell is mimicked/done by cancer cells to invade other cells?
In other words, which cell has a function to invade other tissue?
(a)
Cancer cells have:
1/1+ nuclei/nucleoli
normal cytoplasmic to nucleus ratio
coarse strands of chromatin
abnormal C.M
In a peripheral blood slide, the presence of a large, dark staining cell is normal
true
false
What term describes a somatic cell's need to attach to a surface to be able to divide?
(a)
Normal cells stop dividing when they form a complete monolayer because of ____________ ________
(a)
A variety of drugs/treatments are used to treat cancer cells because of _________ ____________
(a)
Which of the following checkpoints are not passed by mature cells?
G1
G2
G0
M1
Which of the following cells are always dividing?
skin
bone marrow
GI cells
all of the above
What term describes when cells become immature because of DNA damage, losing their structure and function?
(a)
Which of the following cell types mimics normal cell structure despite being malignant, and as such, is easier to treat?
grade 1
grade 3
grade 2
anaplastic
Cancer cells have an altered metabolism, and because of __________ ___________ cancer cells have an increased uptake of glucose and fermentation of glucose to lactate
(a)
Philadelphia chromosome is a translocation between which chromosomes?
23 and 9
9 and 22
10 and 22
9 and 21
Philly chromosome produces a chimeric protein from which genes?
ALB + BCR
ABL + BRC
ABL + BCR
LAB + RCB
What term describes a mutated/overexpressed version of a normal gene?
(a)
Which of the following oncogenes blocks apoptosis?
one that encodes for growth factor
one that encodes for mutant transcription activator
one that codes for BCL-3
one that encodes for BCL-2
Masses in the body- ex: the lungs can be because of a variety of reasons, not just because of cancer/malignant tumors
false
true
Which of the following terms si the most common adaptation to toxin exposure in the body?
dysplasia
atypia
metaplasia
hypertrophy
atrophy
Which type of tumor is mobile (moves when touched), and is not painful?
malignant
benign
very malignant
What term describes atypical metaplasia that involves DNA damage/change? HINT: It is considered pre-neoplastic injury
(a)
Benign tumors cannot cause damage to tissues
true
false
Which of the following is true when it comes to damage involved in a meningioma?
brain can be compressed, causing neurological defecits
can cause endocrine disorders
can cause increased bleeding in menses due to hormone imbalance
can compress the optic/olfactory nerves, causing severe visual field changes
none of the above
Which of the following is an example of a malignant tumor
osteosarcoma
rhabdomyoma
liposarcoma
adenocarcinogenoma
Which of the following is a less aggressive leukemia?
chronic
acute
Hematological neoplasms do not have masses (tumors)
true
false
Which of the following neurological neoplasms is the most aggressive brain cancer?
meningiblastoma
glioblastoma
astrocytoma
meningioma
neurosarcoma
What term describes weight loss in cancer that occurs even if the tumor size is small?
(a)
Which of the following factors destroys damaged connective tissue and remodels the injured area when a wound occurs?
FGF-1
MMP
VEG-F
FGF-2
As vasculature in a tumor _____________ severity of cancer ____________
increases; decreases
decreases; increases
increases; increases
decreases; decreases
Angiostatin, a drug that could possibly block cancer cells from creating new blood vessels, failed because:
wound healing was improved
immune cell fx was compromised
wound healing was impaired
cells could not invade tissue
If there are masses in both lungs, which of the following is possible?
secondary site of cancer (metastasis)
primary cancer
tuberculosis, causing caseous necrosis
lung abcess
