DNA as the Carrier of Genetic Information

Front

Who observed the transformation in Streptococcus pneumoniae in 1928?

Back

Frederick Griffith

Front

What are the two strains of Streptococcus pneumoniae identified by Griffith?

Back

S strain and R strain

Front

What does the S strain of bacteria produce?

Back

Shiny colonies due to a polysaccharide coat

Front

What is the characteristic of the R strain of bacteria?

Back

It lacks a polysaccharide coat and produces rough colonies.

Front

What was the outcome when S strain was injected into mice?

Back

Mice developed pneumonia and died.

Front

What happened when R strain was injected into mice?

Back

Mice lived.

Front

What was the result of injecting heat-killed S strain into mice?

Back

Mice lived.

Front

What was the outcome when heat-killed S strain was combined with R strain and injected into mice?

Back

Mice died and live S strain bacteria were recovered.

Front

What did Griffith conclude from his experiments?

Back

The R strain was transformed by the heat-killed S strain due to a 'transforming principle'.

Front

Who set out to determine the biochemical nature of the 'transforming principle'?

Back

Oswald Avery, Colin MacLeod, and McCarty