Chromosome Mutations

Chromosome Mutations

Multiple Choice

Frameshift mutation

• Addition of one or more nucleic acids

• Removal of one or more nucleic acids

• Replacement of one or more nucleic acids

• When codons shift ---nucleic acids are separated from their original marriage

• Copying or doubling of a sequence

Multiple Choice

Are all mutations harmful?

• Yes, they are caused by toxic chemicals and radiation

• No, all mutations are beneficial

• Yes, mutations cause fatal diseases

• No, some can be useful in a changing environment

Multiple Choice

When an extra base has been added to the sequence of bases, this is what type of mutation?

• Substitution

• Deletion

• Inversion

• Insertion

Multiple Choice

DNA molecule segment is : TTACGCAAG

The mutated DNA segment is TTCGCAAG. This is an example of ___ mutation.

• Substitution

• Deletion

• Insertion

• Inversion

Multiple Choice

What is the correct mRNA strand from this DNA?

CAC-GTG-ACA-GCG

• GTG-CAC-TGT-CGC

• CAC-GUG-ACA-GCG

• GUG-CAC-UGU-CGC

Multiple Choice

Normal-

GAG-CTC-GAC-AGA

Mutant

GAG CTC-CAC-AGA

• no mutation

• substitution

• insertion

• deletion

Multiple Choice

Which change below would result in a different Amino Acid?

3'-GCT-5'

• GTT

• TCT

• TCC

• GCA

Multiple Choice

Which change below would result in a different Amino Acid?

3'-GCT-5'

• GTT

• TCT

• TCC

• GCA

Multiple Choice

A substitution mutation that has no effect

on amino acids sequence

• Insertion Mutation

• Translocation

• Silent Mutation

• Deletion Mutation

Multiple Choice

The chromosomal mutation shown in the image is a

• deletion

• duplication

• inversion

• translocation

Multiple Choice

A piece of the chromosome detaches, turns 180 degrees and reattaches

• deletion

• duplication

• inversion

• translocation

Multiple Choice

A piece of a chromosome is lost

• deletion

• duplication

• inversion

• translocation

Multiple Choice

The chromosomal mutation shown in the image is a

• deletion

• duplication

• inversion

• translocation

Multiple Choice

The chromosomal mutation shown in the image is a

• deletion

• duplication

• inversion

• translocation

Multiple Choice

The chromosomal mutation shown in the image is a

• deletion

• duplication

• inversion

• translocation

Multiple Choice

A piece of one chromosome detaches and re-attaches to a different chromosome

• deletion

• duplication

• inversion

• translocation

Multiple Choice

A piece of a chromosome is copied and remains within the chromosome

• deletion

• duplication

• inversion

• translocation

Multiple Choice

The presence of an extra chromosome, the gamete contains 24 pairs of chromosomes(3 copies instead of 2)

• Trisomy

• Monosomy

Multiple Choice

Which of the following notations best summarizes the karyotype?

• 46,XY, trisomy 13

• 47, XY, trisomy 13

• 46, XY, Patau's Syndrome

• 47, XX, Patau's Syndrome

Multiple Choice

Which of the following notations best summarizes the karyotype?

• 45,XX, Turner's

• 46,XX, Down Syndrome

• 46,XX

• 46,XX, +X

Multiple Choice

What chromosomal disorder can be identified in the karyotype?

• Edward's

• Trisomy X

• Patau's

• Klinefelter's

Multiple Choice

What chromosomal disorder can be identified in the karyotype?

• Edward's

• Trisomy X

• Patau's

• Klinefelter's

Multiple Select

Select all the disorders affected by an extra chromosome (trisomy)

• Edward's

• Patau's

• Klinefelter's

• Turner's

• Down's

Open Ended

Which type of mutation (gene or chromosome) causes more damage and why?