Karyotype Analysis Lesson

Karyotyping (Chromosomes 1 - 5)

Quizz 1

Multiple Choice

Which is chromosome 3?

Multiple Choice

What chromosome is this?

• 1

• 2

• 3

Multiple Choice

Which chromosome do NOT belong to Group A?

Trisomy 3 in non Hodgkin's lymphoma

• More frequently in T-cell lymphomas than in B-cell lymphomas

• Prognosis unknown

Multiple Choice

Which is chromosome 4?

Multiple Choice

Which is Chromosome 5?

Chromosome 5q deletion syndrome

• Acquired, hematological disorder most commonly associated with the myelodysplastic syndrome (MDS).

• Isolated del(5q) in MDS have favorable prognosis with good response with lenalidomide treatment.

• If present with other abnormalities has poor prognosis.

Multiple Choice

Which chromosome has 5q deletion?

3q27 rearrangements (BCL6) in non Hodgkin lymphoma

• BCL6 gene is located at chromosome 3q27

• Relative favorable outcome in BCL6 rearranged Diffused Large B-cell Lymphoma (DLBCL)

Multiple Choice

Which chromosome 3 has abnormality on the q arm?