Standard 3C.3 Mutation

Multiple Choice

A change in a gene, group of genes or chromosome that results in a change in the proteins

• Replication

• Mutations

• Translation

• Transcription

Multiple Choice

When can a mutation be passed on to offspring?

• only when the mutation is present during or occurs during mitosis
• only when the mutation is present during or occurs during meiosis
• when the mutation occurs during mitosis or meiosis
• when the mutation occurs in somatic cells

Multiple Choice

What do mutations change?

• DNA
• Chromosomes
• Genes

Multiple Choice

What are the three types of gene mutation?

• Insertion, Deletion, Subsitution

• Aberration, Deletion, Substitution

• Inversion, Duplication, Insertion

• Insertion, Duplication, Substitution

Multiple Choice

Which statement best defines a mutation?

• a physical trait that negatively impacts the organism

• an adaptive trait that allows the individual to be better fit for survival

• a change in the order, number, or type of bases in the genetic code

• an identical copy of the original DNA strand

Multiple Choice

Chemical or physical agents in the environment that may cause mutations are called:

• mutants

• mutagens

• chromosomal mutations

• missense mutations

Labelling

Label each of the following chromosomal mutations

Drag labels to their correct position on the image

Duplication

Inversion

Deletion

Translocation

Match

Match the following Chromosome Mutations

Deletion

Translocation

Inversion

• Deletion

• Translocation

• Inversion

Multiple Choice

Nondisjunction

• When a segment of a chromosome breaks off.

• When a segment of a chromosome breaks off, flips, and reattaches.

• When a segment of a chromosome breaks and attaches to a non homologous chromosome.

• When entire chromosomes don't separate evenly during meiosis.

• When a segment of a chromosome is copied or doubles.

Multiple Choice

DNA molecule segment is : TTACGCAAG
The mutated DNA segment is TTCGCAAG. This is an example of ___ mutation.

• Substitution
• Deletion
• Insertion
• Inversion

Multiple Choice

Normal-
GAG-CTC-GAC-AGA
Mutant
GAG CTC-CAC-AGA

• no mutation
• substitution
• insertion
• deletion

Multiple Choice

What type of gene mutation has occurred here? Normal-
AGA-TTC-ATA-GCG
Mutant-
AGA-TTC-AAT-AGC-G

• deletion frameshift
• insertion frameshift
• substitution
• nonsense

Multiple Choice

All mutations that involves the change of a single nucleotide.

• Point mutation

• Frameshift mutation

• Insertion mutation

• Deletion mutation

Multiple Choice

Missense, Nonsense, and Silent mutations are all more specific results of a _____ mutation

• Insertion

• Deletion

• Substitution

Multiple Choice

A type of substitution mutation that does no lead to a change in the resulting amino acid sequence.

• Missense

• Nonsense

• Silent

• Frameshift

Multiple Choice

A type of substitution mutation that cause a change that results in a stop codon, thus severely altering the protein.

• Missense

• Nonsense

• Silent

• Frameshift

Multiple Choice

Original DNA = TAC GAC TTG AAT

Mutated DNA = TAC GAC TTG AAT

What type of mutation has occurred?

• Chromosomal mutation

• Point mutation

• Frameshift mutation

• No mutation occurred

Multiple Choice

Original DNA = TAC GAC TTG AAT

Mutated DNA = TAC GAC TCG AAT

What type of mutation has occurred?

• Chromosomal mutation

• Point mutation

• Frameshift mutation

• No mutation occurred

Multiple Choice

What mutation has occurred here?

T-G-A-C-C-A

T-G-A-G-C-A

• Substitution

• Deletion

• Insertion

• Frameshift

Multiple Choice

Normal-
GAG-CTC-GAC-AGA
Mutant
GAG CTC-CAC-AGA

• no mutation
• substitution
• insertion
• deletion

Multiple Choice

What type of Mutation is this to the sentence "THE CAT WAS FUN":

THE BAT WAS FUN

• Substitution Mutation

• Deletion Mutation

• Insertion Mutation

Multiple Choice

Which mutation?

• Deletion

• Insertion

• Substitution

• upside down

Multiple Choice

Which mutation?

• Deletion

• Insertion

• Substitution

• upside down

Multiple Choice

Which type of mutation occurs when there is an addition or removal of a base?

• missense mutation

• nonsense mutation

• frameshift mutation

• point mutation

Multiple Choice

A type of mutation that affect every codon beyond the point of mutation.

• Point Mutation

• Silent Mutation

• Nonsense Mutation

• Frameshift Mutation

Multiple Choice

Why are insertion and deletion (frameshift) mutations so harmful?

• They change all of the codons from the mutation on down the line, which changes the amino acid sequence ultimately changing the protein.

• They insert things that an organism doesn't need.

• They often delete things that organisms need.

• Insertion and deletions are not any more harmful than substitution mutations.

Multiple Choice

ATTTGAGCC- Original

ATTGAGCC - Mutated

The example above is an example of a

• Insertion- Frameshift

• Deletion- Substitution

• Deletion -Frameshift

• All of the above

Multiple Choice

Consider a DNA sequence: TAC GAC TTG AAT. It undergoes a mutation, resulting in a new sequence: TAC GTA CTT GAA T. Identify the type of mutation that has occurred.

• Chromosomal mutation

• Point mutation

• Frameshift mutation due to adding an extra base

• Frameshift mutation due to deletion of a base

Multiple Choice

Consider a scenario where an original DNA sequence, TAC GAC TTG AAT, undergoes a transformation and becomes TAC ACT TGA AT. What type of mutation has occurred?

• Chromosomal mutation

• Point mutation

• Frameshift mutation due to addition of base

• Frameshift mutation due to deletion of base

Multiple Choice

Original: ATC CAT
Mutation: ATC GCAT
What mutation occurred?

• deletion
• insertion
• silent
• transverse

Multiple Choice

A frameshift mutation can occur with either _________ or __________ mutations.

• Addition, division
• Deletion, substitution
• Addition, substitution
• Addition, deletion

Match

Match the following

• Mutation

• Point mutation

• Frameshift mutation

• Silent mutation

• Chromosomal mutation

a change in the DNA sequence

a type of mutation where one to few bases are substituted with different bases

a type of mutation caused by adding or deleting bases, affecting all the codons after the change

a type of mutation that doesn't result in a change in the amino acid sequence (same protein)

a type of mutation where large sections of the chromosome are affected

• a change in the DNA sequence

• a type of mutation where one to few bases are substituted with different bases

• a type of mutation caused by adding or deleting bases, affecting all the codons after the change

• a type of mutation that doesn't result in a change in the amino acid sequence (same protein)

• a type of mutation where large sections of the chromosome are affected