Sequence Alignment

Global alignment is based on ________________

• Needleman-Wunsch algorithm

• Smith-Waterman algorithm

• Dot Matrix algorithm

• Dynamic algorithm

It only finds local regions with the highest level of similarity between the two sequences and aligns these regions without regard for the alignment of the rest of the sequence regions.

This is the description for ____________

• Local alignment

• Global alignment

• Specific alignment

• Universal alignment

The statements below are about dot matrix analysis method EXCEPT:

• It is the most conventional analysis in pairwise alignment.

• The dots appear as colorless dots in the computer screen.

• Dot matrix method is a quantitative.

• Simple analysis to analyze the sequences.

This database is produced at the National Centre for Biotechnology and Information (NCBI) as the part of the International Nucleotide sequence Database collaboration (or) INSDC.

• Genbank

• Uniprot

• phylip

• perl

When you are comparing two sequences of same or different organisms, what is the type of the alignment?

• Global

• Local

• Pairwise sequence

• Multiple sequence

When you are comparing two or more than two sequences of same or different organisms, what is the type of the alignment?

• Global

• Pairwise sequence

• Local

• Multiple Sequence

Which alignment is useful to detect the highly similar region?

• Local

• Global

• Pairwise sequence

• Multiple sequence

Which alignment useful to detect the highly conserved regions?

• Local

• Global

• Pairwise sequence

• Multiple sequence

When two sequences are descended from a common evolutionary origin, they are said to have?

• Homology

• Identity

• Similarity

• None of these

Which approach can be used for aligning more divergent sequences ?

• LOCAL

• GLOBAL

• BLAST

• NONE