Protein trafficking by secretary pathway

........is the transport of proteins to their correct subcellular compartments or to the extracellular space

• Secretary pathway

• Protein trafficking

• Transcription

• Translation

secretory pathway refers to the ................, Golgi apparatus and the vesicles that travel in between them as well as the cell

membrane and lysosomes.

• Endoplasmic reticulum

• Golgi bodies

• Both

• None of the above

The microsomes are purified and treated with a protease in the presence and absence of a

• Detergent

• Enzyme

• Mitochondria

• Endoplasm

When cells are homogenized, the rough ER breaks up into small closed vesicles, termed ,

• endoplasmic reticulum

• Rough ER

• rough microsomes

• None of the above

These red dotes showes the...

• Newly made secretary protein

• Permissiveness

• ER

• None of the above

Secretary protein moves from cytosol → rough ER → ER-to-Golgi transport vesicles → Golgi cisternae → secretory vesicles and finally is exocytosed.

• True

• False

By cisternal migration, ........... with their luminal protein cargo move through the Golgi complex to the trans-Golgi reticulum.

• Golgi complex

• Trans golgi

• cis-Golgi vesicles

• All of the above

The pathway for the maturation of secretory proteins elucidated by ........, .........., and .......... in yeasts, algae, fibroblasts, and pancreatic acinar cells is thought to function in all eukaryotic cells.

• autoradiographic

• genetic

• electron microscope studies

• All of the above

........... that modify secretory proteins come to be localized in the correct organelle

• Enzymes

• Golgi complex

• Protein

• ER

When proteins are released into the cytosole with an organelle specific targeting sequence are imported into the....

• Nucleus

• Endoplasmic reticulum

• Mitochondria

• Celo surface