6-PHARMACOKINETICS M2

The precursor of________ enters the brain as levodopa

• Penicillin

• Dopamine

• Phenytoin

• Streptomycin

The majority of excretion of drug and its metabolites is through

• Sweat

• Urine

• Faeces

• Exhaled air

Pharmacokinetics is

• Study of drug effects

• Study of drug movements in the body

• Study of drug interactions

• None of the above

Major mechanism of transport of drug across biological membrane

• Active transport

• Passive diffusion

• Facilitated diffusion

• endocytosis

Which drug irritates gastric mucosa during prolonged contact

• Pencillin

• Aspirin

• 5-fluorouracil

• Metazolone

Salicylates is an example of which type of reaction?

• sulphation

• Glycine conjugation

• Glutathione conjugation

• methylation

Which synthetic reaction requires enzyme UDP-glucuronosyltransferase(UGT)

• Acetylation

• Glucuronide conjugation

• Sulphate conjugation

• Glutathione conjugation

Acidic drugs are ionized at

• Acidic pH

• Alkaline

• Neutral pH

• None

Basic drugs are absorbed from

• stomach

• interstine

• Both a and b

• liver

The statement about acidic drug which is true

• Best absorbed in alkaline medium

• Best absorbed in acidic medium

• Not absorbed in acidic medi-um

• Binds to alpha glycoprotein