Basic Biopharmaceutics Quiz

The place where a drug causes an effect to occur is called the

• site of action.

• site of administration.

• therapeutic window.

• minimum toxic concentration (MTC).

When a drug produces an effect, it is acting at a/an __________ level.

• tissue
• atomic

• molecular

• organ

Drug action can be caused by a

• physical action, such as a protective ointment.

• chemical action, such as an antacid neutralizing acidity.

• osmotic action, such as moving water out of tissues into blood.

• all of the above.

An antagonist will

• not bind to a receptor.

• accelerate a normal body process.

• prevent other drugs from binding to a receptor.

• cause extended stimulation of receptors.

In a blood concentration–time curve, the range between the minimum toxic concentration (MTC) and the minimum effective concentration (MEC) is called the

• onset of action.

• concentration at site of action.

• duration of action.

• therapeutic window.

The time a drug’s blood concentration is above the MTC is called the

• onset of action.

• duration of action.

• concentration at site of action.

• none of the above.

When studying concentration and effect, the ________ is the time MEC is reached and the response occurs.

• therapeutic window

• MTC

• onset of action

• duration of action

Which drug would not typically be monitored with peak and trough blood concentrations?

• vancomycin

• valproic acid

• promethazine

• phenytoin

If the blood concentration–time profile reflects the amount of drug at the site of action, the maximum therapeutic response would occur

• at the onset of action.

• at the MEC.

• at the peak blood concentration.

• when elimination is the predominant process.

The transfer of a drug out of a dosage form and into the blood is called

• absorption.

• dissolution.

• metabolism.

• elimination.