Hypersensitivity

Hypersensitivity

University

8 Qs

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Hypersensitivity

Hypersensitivity

Assessment

Quiz

Science

University

Practice Problem

Medium

Created by

Joseph Tiong

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8 questions

Show all answers

1.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

In Type I hypersensitivity reactions, the cross-linking of IgE antibodies bound to Fc receptors on mast cells and basophils leads to the release of various mediators. Which of the following is a primary mediator released during this process, and what is its role in the hypersensitivity reaction?

IL-4; Promotes differentiation of Th1 cells

Histamine; Increases vascular permeability and smooth muscle contraction

  • TNF-alpha; Induces apoptosis in infected cells

  • IL-10; Suppresses inflammatory responses

2.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which of the following best describes the primary mechanism of tissue damage in type II hypersensitivity reactions?

Immune complex deposition

 Delayed T-cell-mediated response

Production of granulomas by macrophages

Direct lysis of cells by NK cells

3.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Steve has been exposed to Strep A bacteria and been diagnosed with acute rheumatic fever. Why is he at risk of heart complications?

Immune complexes deposit in the heart tissue causing inflammation.

Antibodies cross-react with heart tissue leading to cell damage.

Eosinophils directly attack the heart tissue.

Granulomas form in the heart leading to tissue damage.

4.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which of the following diseases is associated with Type III hypersensitivity?

Systemic Lupus Erythematosus (SLE)

Asthma

Acute Rheumatic Fever

Allergic Rhinitis

5.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which of the following mechanisms is involved in Type III hypersensitivity?

  1. Direct toxicity by T cells

Binding of IgM or IgG antibodies to self-antigens on tissues

Release of histamine by mast cells

  1. Release of cytokines by immune complexes to activate neutrophils

6.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

How long after exposure does a Type IV hypersensitivity reaction typically manifest?

1-2 days

Within minutes

Within hours

3-7 days

7.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which of the following conditions is an example of a Type IV hypersensitivity reaction?

Tuberculosis skin test

Anaphylaxis

Haemolytic anemia

Rheumatoid arthritis

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