Biochemistry- General Reactions of AA & Urea cycle

Match the following

A. Transamination 1. NADPH

B. GLutamate Dehydrogenase 2. PLP

C. Decarboxylation 3. FMN

D. Amino acid Oxidase 4. PLP

• A- 2

  B- 4

  C- 1

  D- 3

• A- 3

  B- 1

  C- 2

  D- 4

• A- 3

  B- 2

  C- 1

  D- 4

• A- 4

  B- 1

  C- 2

  D- 3

Which of the following hormone inhibits glutamate dehydrogenase

• ATP

• GTP

• Steroid

• All the above

What is the purpose of transamination under normal circumstances

• To generate energy

• To generate essential amino acids

• To produce glutamate

• All the above

Answer explanation

Correct answer C- To produce glutamte

wrong options are

A- Energy generation happens in exces amino acids but question asked in normal circumstances

B- Helps in synthesis of non-essential amino acids

D- All the above is wrong.

Oxidation of glutamate by glutamate dehydrogenase (GDH) with the intermediate of

• Glutamate

• Iminoglutarate

• Keto acid

• all the above

Which of the following statement is wrong with transamination

1. 1. Transaminases are useful in diagnosis

2. 2. These reactions are reversible

3. 3. All amino acids participate in these reactions

4. 4. There is no free ammonia liberated

• 1

• 2

• 3

• 4

No of ATP utilized in urea cycle

• 1

• 2

• 3

• 4

Which of the following is wrong with urea cycle

1. 1. Among 5 reactions 2 will happen in mitochondria and rest of reactions in cytosol.

2. 2. carbon source in urea is CO2

3. 3. One of amine source in urea is Ammonia

4. 4. The other amine source in urea is Aspartate

• 1

• 2

• 3

• None of the above

Name the two basic amino acids that participate in Urea cycle

• Ornitine and citrulline

• Ornitine and Aspartate

• Aspartate and Citrulline

• Citrulline and arginosuccinate

Name the enzyme of urea cycle which is only present in liver

• Asparginase

• Arginase

• Aspartase

• All the above

What is the fate of Fumarate in urea cycle

• TCA cycle

• Gluconeogenesis

• Both A & B

• None of the above