Which of the following proteins is the key regulator of the extrinsic pathway of apoptosis?

• Fas

• FasL

• Caspase-8

• Bid

What is the difference between apoptosis and necrosis?

• Apoptosis is inflammatory, while necrosis is not.

• Apoptosis is programmed, while necrosis is unprogrammed

• Apoptosis occurs in healthy cells, while necrosis occurs in damaged cells.

• Apoptosis is programmed, while necrosis is unprogrammed.

What is the term for the process by which mitochondria release pro-apoptotic proteins, such as cytochrome c, into the cytosol?

• Mitochondrial outer membrane permeabilization (MOMP)

• Mitochondrial inner membrane permeabilization (MIMP)

• Mitochondrial permeability transition(MPT)

• Mitochondrial swelling

Which of the following is the characteristics of apoptotic cells?

• Swelling of the cell

• Fragmentation of the nucleus

• Increased cell division

• Enhanced metabolic activity

What is the role of mitochondria in apoptosis?

• To generate energy for cell

• To regulate cell growth

• To release pro-apoptotic proteins

• To synthesize proteins

Which of the following caspases is considered the "executioner" caspase?

• Caspase-8

• Caspase-9

• Caspase-3

• Caspase-12

Which of the following is a consequence of unregulated apoptosis?

• Cancer

• Autoimmune disease

• Neurodegenerative disease

• All of the above

What is the role of cytochrome c in apoptosis?

• To generate energy for the cell

• To regulate cell growth

• To activate caspases

• To synthesize proteins

Which of the following is a characteristic of the extrinsic pathway of apoptosis?

• Involves the mitochondria

• Involves death receptors

• Involves the nucleus

• Involves the endoplasmic reticulum

What is the term for the process by which cells undergo apoptosis in response to viral infection?

• Apoptosis

• Necrosis

• Autophagy

• Pyroptosis